ProfileGDS5420 / 243667_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 66% 72% 68% 57% 58% 63% 76% 73% 56% 64% 64% 79% 60% 60% 81% 83% 65% 61% 69% 63% 75% 65% 66% 76% 66% 74% 78% 76% 77% 73% 64% 82% 56% 66% 74% 68% 81% 78% 56% 82% 80% 77% 62% 61% 57% 61% 61% 62% 58% 58% 60% 54% 52% 64% 71% 57% 80% 61% 66% 69% 73% 60% 80% 66% 53% 60% 67% 58% 60% 63% 54% 62% 57% 62% 66% 65% 72% 58% 58% 67% 59% 77% 76% 51% 59% 66% 80% 57% 56% 79% 83% 61% 64% 61% 70% 66% 54% 79% 58% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose477.9866
GSM1296119B_lesional_pre-dose621.872
GSM1296076C_lesional_pre-dose466.0268
GSM1296092D_lesional_pre-dose243.4957
GSM1296103E_lesional_pre-dose279.4358
GSM1296078F_lesional_pre-dose349.9263
GSM1296107G_lesional_pre-dose823.7876
GSM1296109H_lesional_pre-dose688.6273
GSM1296080I_lesional_pre-dose241.6356
GSM1296090J_lesional_pre-dose385.5164
GSM1296074K_lesional_pre-dose367.2364
GSM1296111L_lesional_pre-dose1001.9579
GSM1296099M_lesional_pre-dose334.2660
GSM1296086O_lesional_pre-dose291.4360
GSM1296117P_lesional_pre-dose1082.2181
GSM1296113Q_lesional_pre-dose1248.1183
GSM1296096R_lesional_pre-dose433.4965
GSM1296105S_lesional_pre-dose352.661
GSM1296098T_lesional_pre-dose533.9769
GSM1296101U_lesional_pre-dose380.3463
GSM1296121V_lesional_pre-dose757.1475
GSM1296088W_lesional_pre-dose430.6965
GSM1296082X_lesional_pre-dose421.0566
GSM1296115Y_lesional_pre-dose813.7776
GSM1296084Z_lesional_pre-dose458.3166
GSM1296072B_lesional_day8708.9674
GSM1296069L_lesional_day8934.0578
GSM1296071P_lesional_day8833.4276
GSM1296070Y_lesional_day8841.2577
GSM1296073V_lesional_day8686.8273
GSM1296034A_lesional_day15423.8364
GSM1296041G_lesional_day151161.0782
GSM1296035R_lesional_day15253.9656
GSM1296038U_lesional_day15449.4466
GSM1296047B_lesional_day15720.5174
GSM1296039E_lesional_day15482.3868
GSM1296042H_lesional_day151099.7681
GSM1296043L_lesional_day15923.3178
GSM1296037M_lesional_day15264.8656
GSM1296046P_lesional_day151145.2782
GSM1296044Q_lesional_day151062.3980
GSM1296045Y_lesional_day15861.1677
GSM1296025C_lesional_day15340.8462
GSM1296033D_lesional_day15342.9461
GSM1296027I_lesional_day15251.8357
GSM1296032J_lesional_day15336.6661
GSM1296024K_lesional_day15330.5261
GSM1296031W_lesional_day15376.8662
GSM1296028X_lesional_day15286.1858
GSM1296029Z_lesional_day15280.4858
GSM1296026F_lesional_day15304.6460
GSM1296030O_lesional_day15199.6454
GSM1296040S_lesional_day15197.7252
GSM1296036T_lesional_day15429.5964
GSM1296048V_lesional_day15592.1571
GSM1296059A_lesional_day43261.7957
GSM1296066G_lesional_day431044.6380
GSM1296060R_lesional_day43350.5761
GSM1296063U_lesional_day43447.1666
GSM1296064E_lesional_day43507.9769
GSM1296067H_lesional_day43704.0373
GSM1296062M_lesional_day43335.4660
GSM1296068Q_lesional_day431033.0280
GSM1296050C_lesional_day43444.2466
GSM1296057D_lesional_day43208.1753
GSM1296052I_lesional_day43312.2660
GSM1296054J_lesional_day43508.9767
GSM1296049K_lesional_day43283.2458
GSM1296055W_lesional_day43321.2860
GSM1296053X_lesional_day43386.1563
GSM1296058Z_lesional_day43211.8654
GSM1296051F_lesional_day43340.8762
GSM1296056O_lesional_day43257.5457
GSM1296065S_lesional_day43356.9862
GSM1296061T_lesional_day43487.1366
GSM1296095A_non-lesional_pre-dose411.1865
GSM1296120B_non-lesional_pre-dose654.7972
GSM1296077C_non-lesional_pre-dose274.4258
GSM1296093D_non-lesional_pre-dose291.5758
GSM1296104E_non-lesional_pre-dose465.9967
GSM1296079F_non-lesional_pre-dose289.9259
GSM1296108G_non-lesional_pre-dose881.5577
GSM1296110H_non-lesional_pre-dose801.4776
GSM1296081I_non-lesional_pre-dose169.4451
GSM1296091J_non-lesional_pre-dose283.6159
GSM1296075K_non-lesional_pre-dose416.3966
GSM1296112L_non-lesional_pre-dose1023.4480
GSM1296100M_non-lesional_pre-dose273.2157
GSM1296087O_non-lesional_pre-dose221.7256
GSM1296118P_non-lesional_pre-dose972.9379
GSM1296114Q_non-lesional_pre-dose1233.5283
GSM1296097R_non-lesional_pre-dose345.561
GSM1296106S_non-lesional_pre-dose418.264
GSM1296102U_non-lesional_pre-dose351.5461
GSM1296122V_non-lesional_pre-dose587.3970
GSM1296089W_non-lesional_pre-dose475.9766
GSM1296083X_non-lesional_pre-dose220.6254
GSM1296116Y_non-lesional_pre-dose963.379
GSM1296085Z_non-lesional_pre-dose273.8158