ProfileGDS5420 / 243469_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 58% 59% 56% 40% 51% 61% 68% 71% 57% 42% 57% 71% 51% 36% 72% 75% 51% 53% 62% 45% 63% 55% 44% 65% 55% 59% 74% 72% 73% 61% 60% 71% 51% 57% 65% 44% 69% 75% 52% 74% 74% 72% 69% 50% 39% 51% 68% 56% 48% 48% 68% 43% 56% 60% 60% 47% 73% 52% 52% 52% 74% 45% 75% 69% 40% 48% 58% 61% 56% 50% 44% 55% 41% 52% 61% 54% 66% 73% 54% 44% 64% 74% 83% 35% 51% 69% 75% 45% 47% 75% 82% 54% 62% 55% 63% 62% 53% 78% 50% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose279.0258
GSM1296119B_lesional_pre-dose309.1359
GSM1296076C_lesional_pre-dose232.8156
GSM1296092D_lesional_pre-dose78.8140
GSM1296103E_lesional_pre-dose182.3251
GSM1296078F_lesional_pre-dose310.8161
GSM1296107G_lesional_pre-dose519.568
GSM1296109H_lesional_pre-dose613.4971
GSM1296080I_lesional_pre-dose254.0757
GSM1296090J_lesional_pre-dose97.4642
GSM1296074K_lesional_pre-dose237.0657
GSM1296111L_lesional_pre-dose613.5771
GSM1296099M_lesional_pre-dose190.451
GSM1296086O_lesional_pre-dose64.3636
GSM1296117P_lesional_pre-dose640.5872
GSM1296113Q_lesional_pre-dose772.7775
GSM1296096R_lesional_pre-dose182.1151
GSM1296105S_lesional_pre-dose214.1953
GSM1296098T_lesional_pre-dose361.1862
GSM1296101U_lesional_pre-dose129.1945
GSM1296121V_lesional_pre-dose377.263
GSM1296088W_lesional_pre-dose232.555
GSM1296082X_lesional_pre-dose101.9444
GSM1296115Y_lesional_pre-dose436.3465
GSM1296084Z_lesional_pre-dose226.3455
GSM1296072B_lesional_day8302.1959
GSM1296069L_lesional_day8710.9574
GSM1296071P_lesional_day8640.7772
GSM1296070Y_lesional_day8679.7473
GSM1296073V_lesional_day8328.5761
GSM1296034A_lesional_day1533960
GSM1296041G_lesional_day15589.9371
GSM1296035R_lesional_day15181.551
GSM1296038U_lesional_day15273.0957
GSM1296047B_lesional_day15421.9665
GSM1296039E_lesional_day15112.6644
GSM1296042H_lesional_day15543.6169
GSM1296043L_lesional_day15767.3575
GSM1296037M_lesional_day15204.4852
GSM1296046P_lesional_day15743.0474
GSM1296044Q_lesional_day15717.974
GSM1296045Y_lesional_day15652.0172
GSM1296025C_lesional_day15552.1669
GSM1296033D_lesional_day15169.4350
GSM1296027I_lesional_day1574.0839
GSM1296032J_lesional_day15186.4351
GSM1296024K_lesional_day15516.8968
GSM1296031W_lesional_day15270.0356
GSM1296028X_lesional_day15146.7848
GSM1296029Z_lesional_day15153.6948
GSM1296026F_lesional_day15483.1768
GSM1296030O_lesional_day1592.8243
GSM1296040S_lesional_day15246.2256
GSM1296036T_lesional_day15344.6560
GSM1296048V_lesional_day15328.6460
GSM1296059A_lesional_day43140.8147
GSM1296066G_lesional_day43697.8373
GSM1296060R_lesional_day43200.7352
GSM1296063U_lesional_day43191.1452
GSM1296064E_lesional_day43191.3352
GSM1296067H_lesional_day43719.7974
GSM1296062M_lesional_day43127.9845
GSM1296068Q_lesional_day43774.8975
GSM1296050C_lesional_day43541.7269
GSM1296057D_lesional_day4389.1940
GSM1296052I_lesional_day43136.9748
GSM1296054J_lesional_day43301.5658
GSM1296049K_lesional_day43341.5761
GSM1296055W_lesional_day43255.6456
GSM1296053X_lesional_day43177.6850
GSM1296058Z_lesional_day43111.144
GSM1296051F_lesional_day43222.455
GSM1296056O_lesional_day4389.9641
GSM1296065S_lesional_day43197.3252
GSM1296061T_lesional_day43359.7961
GSM1296095A_non-lesional_pre-dose218.2754
GSM1296120B_non-lesional_pre-dose459.2666
GSM1296077C_non-lesional_pre-dose677.6373
GSM1296093D_non-lesional_pre-dose231.7954
GSM1296104E_non-lesional_pre-dose115.9744
GSM1296079F_non-lesional_pre-dose393.4364
GSM1296108G_non-lesional_pre-dose717.7474
GSM1296110H_non-lesional_pre-dose1223.0983
GSM1296081I_non-lesional_pre-dose56.5135
GSM1296091J_non-lesional_pre-dose176.4751
GSM1296075K_non-lesional_pre-dose501.8669
GSM1296112L_non-lesional_pre-dose771.9775
GSM1296100M_non-lesional_pre-dose134.4545
GSM1296087O_non-lesional_pre-dose123.7647
GSM1296118P_non-lesional_pre-dose793.5175
GSM1296114Q_non-lesional_pre-dose1158.1682
GSM1296097R_non-lesional_pre-dose223.7654
GSM1296106S_non-lesional_pre-dose365.262
GSM1296102U_non-lesional_pre-dose246.1455
GSM1296122V_non-lesional_pre-dose395.6363
GSM1296089W_non-lesional_pre-dose366.0762
GSM1296083X_non-lesional_pre-dose206.3553
GSM1296116Y_non-lesional_pre-dose912.8278
GSM1296085Z_non-lesional_pre-dose168.750