ProfileGDS5420 / 243132_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 51% 28% 37% 33% 55% 33% 42% 52% 45% 28% 38% 40% 47% 30% 43% 43% 40% 48% 64% 47% 36% 29% 28% 45% 45% 30% 46% 47% 39% 34% 65% 42% 44% 46% 31% 42% 39% 39% 48% 48% 46% 41% 53% 19% 32% 41% 56% 48% 30% 53% 46% 29% 54% 63% 37% 51% 41% 40% 39% 41% 44% 59% 38% 25% 38% 35% 41% 46% 41% 31% 35% 37% 25% 43% 65% 42% 33% 50% 48% 45% 47% 47% 54% 50% 37% 44% 42% 55% 29% 50% 48% 41% 43% 56% 41% 33% 48% 49% 49% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose182.7151
GSM1296119B_lesional_pre-dose48.6928
GSM1296076C_lesional_pre-dose74.1737
GSM1296092D_lesional_pre-dose50.0333
GSM1296103E_lesional_pre-dose225.9155
GSM1296078F_lesional_pre-dose55.4133
GSM1296107G_lesional_pre-dose114.9742
GSM1296109H_lesional_pre-dose212.1952
GSM1296080I_lesional_pre-dose110.0245
GSM1296090J_lesional_pre-dose38.7928
GSM1296074K_lesional_pre-dose67.738
GSM1296111L_lesional_pre-dose102.640
GSM1296099M_lesional_pre-dose145.8847
GSM1296086O_lesional_pre-dose44.9230
GSM1296117P_lesional_pre-dose127.2243
GSM1296113Q_lesional_pre-dose137.9243
GSM1296096R_lesional_pre-dose86.1640
GSM1296105S_lesional_pre-dose158.8748
GSM1296098T_lesional_pre-dose399.7164
GSM1296101U_lesional_pre-dose149.5447
GSM1296121V_lesional_pre-dose75.7936
GSM1296088W_lesional_pre-dose41.0929
GSM1296082X_lesional_pre-dose37.8728
GSM1296115Y_lesional_pre-dose135.2745
GSM1296084Z_lesional_pre-dose126.5845
GSM1296072B_lesional_day854.9630
GSM1296069L_lesional_day8160.6246
GSM1296071P_lesional_day8167.1847
GSM1296070Y_lesional_day8105.0739
GSM1296073V_lesional_day864.8434
GSM1296034A_lesional_day15463.0465
GSM1296041G_lesional_day15111.6742
GSM1296035R_lesional_day15113.0644
GSM1296038U_lesional_day15136.5346
GSM1296047B_lesional_day1561.4331
GSM1296039E_lesional_day15104.6442
GSM1296042H_lesional_day15100.1239
GSM1296043L_lesional_day15102.2339
GSM1296037M_lesional_day15163.8948
GSM1296046P_lesional_day15177.3748
GSM1296044Q_lesional_day15151.8946
GSM1296045Y_lesional_day15121.8441
GSM1296025C_lesional_day15200.6653
GSM1296033D_lesional_day1521.0719
GSM1296027I_lesional_day1545.9132
GSM1296032J_lesional_day1597.9741
GSM1296024K_lesional_day15239.7556
GSM1296031W_lesional_day15164.4648
GSM1296028X_lesional_day1544.7330
GSM1296029Z_lesional_day15210.4453
GSM1296026F_lesional_day15125.5246
GSM1296030O_lesional_day1534.8129
GSM1296040S_lesional_day15223.5454
GSM1296036T_lesional_day15397.1663
GSM1296048V_lesional_day1580.6337
GSM1296059A_lesional_day43182.551
GSM1296066G_lesional_day43114.1241
GSM1296060R_lesional_day4390.5940
GSM1296063U_lesional_day4391.7439
GSM1296064E_lesional_day4392.1141
GSM1296067H_lesional_day43136.0444
GSM1296062M_lesional_day43305.159
GSM1296068Q_lesional_day43102.2938
GSM1296050C_lesional_day4335.7225
GSM1296057D_lesional_day4378.7138
GSM1296052I_lesional_day4357.2635
GSM1296054J_lesional_day43104.641
GSM1296049K_lesional_day43129.9546
GSM1296055W_lesional_day43106.3141
GSM1296053X_lesional_day4349.431
GSM1296058Z_lesional_day4361.7835
GSM1296051F_lesional_day4371.137
GSM1296056O_lesional_day4330.6625
GSM1296065S_lesional_day43110.6143
GSM1296061T_lesional_day43453.3265
GSM1296095A_non-lesional_pre-dose100.4642
GSM1296120B_non-lesional_pre-dose70.5333
GSM1296077C_non-lesional_pre-dose164.9650
GSM1296093D_non-lesional_pre-dose163.7948
GSM1296104E_non-lesional_pre-dose125.2245
GSM1296079F_non-lesional_pre-dose133.9547
GSM1296108G_non-lesional_pre-dose152.9147
GSM1296110H_non-lesional_pre-dose251.3154
GSM1296081I_non-lesional_pre-dose158.9250
GSM1296091J_non-lesional_pre-dose73.1337
GSM1296075K_non-lesional_pre-dose106.7444
GSM1296112L_non-lesional_pre-dose128.0842
GSM1296100M_non-lesional_pre-dose246.7455
GSM1296087O_non-lesional_pre-dose39.2429
GSM1296118P_non-lesional_pre-dose192.1650
GSM1296114Q_non-lesional_pre-dose175.5948
GSM1296097R_non-lesional_pre-dose100.7141
GSM1296106S_non-lesional_pre-dose118.6743
GSM1296102U_non-lesional_pre-dose268.1756
GSM1296122V_non-lesional_pre-dose111.3741
GSM1296089W_non-lesional_pre-dose61.833
GSM1296083X_non-lesional_pre-dose155.6648
GSM1296116Y_non-lesional_pre-dose190.0849
GSM1296085Z_non-lesional_pre-dose165.0249