ProfileGDS5420 / 243015_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 32% 17% 23% 18% 23% 18% 26% 23% 22% 29% 33% 14% 20% 14% 29% 31% 27% 21% 19% 13% 20% 14% 31% 19% 12% 17% 20% 25% 23% 10% 21% 20% 22% 28% 20% 18% 23% 23% 20% 30% 31% 25% 19% 24% 32% 29% 18% 12% 27% 15% 18% 13% 21% 30% 19% 27% 27% 18% 32% 38% 22% 21% 24% 19% 19% 31% 30% 18% 13% 12% 12% 20% 10% 30% 15% 36% 20% 15% 18% 19% 19% 26% 25% 5% 22% 30% 20% 21% 8% 24% 35% 25% 31% 12% 15% 23% 8% 26% 16% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose51.232
GSM1296119B_lesional_pre-dose23.0117
GSM1296076C_lesional_pre-dose31.0423
GSM1296092D_lesional_pre-dose17.9318
GSM1296103E_lesional_pre-dose27.0823
GSM1296078F_lesional_pre-dose21.1918
GSM1296107G_lesional_pre-dose43.4426
GSM1296109H_lesional_pre-dose33.623
GSM1296080I_lesional_pre-dose24.7822
GSM1296090J_lesional_pre-dose40.4729
GSM1296074K_lesional_pre-dose50.2433
GSM1296111L_lesional_pre-dose19.1914
GSM1296099M_lesional_pre-dose22.9320
GSM1296086O_lesional_pre-dose14.2914
GSM1296117P_lesional_pre-dose52.929
GSM1296113Q_lesional_pre-dose68.4331
GSM1296096R_lesional_pre-dose34.5827
GSM1296105S_lesional_pre-dose25.9421
GSM1296098T_lesional_pre-dose29.2319
GSM1296101U_lesional_pre-dose13.5313
GSM1296121V_lesional_pre-dose25.7820
GSM1296088W_lesional_pre-dose13.2214
GSM1296082X_lesional_pre-dose45.0731
GSM1296115Y_lesional_pre-dose24.6219
GSM1296084Z_lesional_pre-dose13.912
GSM1296072B_lesional_day821.317
GSM1296069L_lesional_day831.9520
GSM1296071P_lesional_day842.1125
GSM1296070Y_lesional_day836.0523
GSM1296073V_lesional_day811.3210
GSM1296034A_lesional_day1528.3321
GSM1296041G_lesional_day1528.6720
GSM1296035R_lesional_day1523.0922
GSM1296038U_lesional_day1539.1828
GSM1296047B_lesional_day153020
GSM1296039E_lesional_day1521.6718
GSM1296042H_lesional_day1536.6723
GSM1296043L_lesional_day1537.123
GSM1296037M_lesional_day1525.6120
GSM1296046P_lesional_day1560.430
GSM1296044Q_lesional_day1564.0831
GSM1296045Y_lesional_day1544.4425
GSM1296025C_lesional_day1522.9619
GSM1296033D_lesional_day1528.9924
GSM1296027I_lesional_day1543.532
GSM1296032J_lesional_day1543.429
GSM1296024K_lesional_day1519.5718
GSM1296031W_lesional_day1512.9812
GSM1296028X_lesional_day1536.727
GSM1296029Z_lesional_day1514.4715
GSM1296026F_lesional_day1521.9218
GSM1296030O_lesional_day1510.7913
GSM1296040S_lesional_day1526.1421
GSM1296036T_lesional_day1551.9630
GSM1296048V_lesional_day1525.1419
GSM1296059A_lesional_day4335.9527
GSM1296066G_lesional_day4346.6327
GSM1296060R_lesional_day4319.4518
GSM1296063U_lesional_day4357.7332
GSM1296064E_lesional_day4378.1238
GSM1296067H_lesional_day4331.6622
GSM1296062M_lesional_day4324.2921
GSM1296068Q_lesional_day4342.1524
GSM1296050C_lesional_day4324.0519
GSM1296057D_lesional_day4319.6419
GSM1296052I_lesional_day4343.4631
GSM1296054J_lesional_day4348.8730
GSM1296049K_lesional_day4321.0118
GSM1296055W_lesional_day4314.113
GSM1296053X_lesional_day4312.412
GSM1296058Z_lesional_day439.7312
GSM1296051F_lesional_day4324.8720
GSM1296056O_lesional_day439.4910
GSM1296065S_lesional_day4346.8230
GSM1296061T_lesional_day4318.0215
GSM1296095A_non-lesional_pre-dose68.9336
GSM1296120B_non-lesional_pre-dose27.9920
GSM1296077C_non-lesional_pre-dose15.9615
GSM1296093D_non-lesional_pre-dose22.118
GSM1296104E_non-lesional_pre-dose24.1719
GSM1296079F_non-lesional_pre-dose24.0719
GSM1296108G_non-lesional_pre-dose40.126
GSM1296110H_non-lesional_pre-dose42.5125
GSM1296081I_non-lesional_pre-dose4.055
GSM1296091J_non-lesional_pre-dose2622
GSM1296075K_non-lesional_pre-dose45.9230
GSM1296112L_non-lesional_pre-dose33.620
GSM1296100M_non-lesional_pre-dose25.9321
GSM1296087O_non-lesional_pre-dose7.388
GSM1296118P_non-lesional_pre-dose39.7524
GSM1296114Q_non-lesional_pre-dose82.5235
GSM1296097R_non-lesional_pre-dose31.4125
GSM1296106S_non-lesional_pre-dose54.2431
GSM1296102U_non-lesional_pre-dose12.6412
GSM1296122V_non-lesional_pre-dose19.9915
GSM1296089W_non-lesional_pre-dose32.7723
GSM1296083X_non-lesional_pre-dose7.418
GSM1296116Y_non-lesional_pre-dose50.4426
GSM1296085Z_non-lesional_pre-dose17.516