ProfileGDS5420 / 242722_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 75% 83% 72% 62% 73% 70% 88% 89% 48% 68% 69% 84% 68% 60% 83% 91% 80% 64% 70% 76% 83% 69% 73% 91% 61% 77% 77% 74% 87% 83% 65% 91% 76% 66% 73% 72% 85% 78% 54% 76% 75% 78% 55% 47% 40% 49% 55% 54% 50% 45% 55% 48% 75% 59% 82% 77% 88% 65% 69% 77% 66% 59% 68% 52% 54% 41% 56% 55% 54% 54% 58% 60% 64% 62% 62% 73% 74% 59% 62% 65% 59% 75% 79% 59% 57% 62% 71% 63% 40% 74% 80% 62% 61% 54% 64% 58% 59% 77% 58% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose768.4175
GSM1296119B_lesional_pre-dose1256.3483
GSM1296076C_lesional_pre-dose629.772
GSM1296092D_lesional_pre-dose327.6562
GSM1296103E_lesional_pre-dose703.0973
GSM1296078F_lesional_pre-dose550.6870
GSM1296107G_lesional_pre-dose1835.588
GSM1296109H_lesional_pre-dose1960.5689
GSM1296080I_lesional_pre-dose134.8648
GSM1296090J_lesional_pre-dose481.9768
GSM1296074K_lesional_pre-dose501.7369
GSM1296111L_lesional_pre-dose1355.7284
GSM1296099M_lesional_pre-dose513.1868
GSM1296086O_lesional_pre-dose296.1960
GSM1296117P_lesional_pre-dose1264.5683
GSM1296113Q_lesional_pre-dose2102.7291
GSM1296096R_lesional_pre-dose1072.1880
GSM1296105S_lesional_pre-dose415.1964
GSM1296098T_lesional_pre-dose574.3870
GSM1296101U_lesional_pre-dose847.4176
GSM1296121V_lesional_pre-dose1309.583
GSM1296088W_lesional_pre-dose536.7369
GSM1296082X_lesional_pre-dose680.2273
GSM1296115Y_lesional_pre-dose2328.8391
GSM1296084Z_lesional_pre-dose333.3161
GSM1296072B_lesional_day8855.2477
GSM1296069L_lesional_day8859.7177
GSM1296071P_lesional_day8747.8674
GSM1296070Y_lesional_day81674.7187
GSM1296073V_lesional_day81289.1483
GSM1296034A_lesional_day15452.6965
GSM1296041G_lesional_day152299.6591
GSM1296035R_lesional_day15855.9276
GSM1296038U_lesional_day15446.8466
GSM1296047B_lesional_day15686.3873
GSM1296039E_lesional_day15634.7172
GSM1296042H_lesional_day151457.185
GSM1296043L_lesional_day15895.1378
GSM1296037M_lesional_day15226.3754
GSM1296046P_lesional_day15831.8976
GSM1296044Q_lesional_day15759.8675
GSM1296045Y_lesional_day15920.478
GSM1296025C_lesional_day15226.9155
GSM1296033D_lesional_day15137.7447
GSM1296027I_lesional_day1579.8940
GSM1296032J_lesional_day15166.4649
GSM1296024K_lesional_day15232.8455
GSM1296031W_lesional_day15227.1654
GSM1296028X_lesional_day15164.8250
GSM1296029Z_lesional_day15124.9745
GSM1296026F_lesional_day15222.0755
GSM1296030O_lesional_day15134.6648
GSM1296040S_lesional_day15794.3275
GSM1296036T_lesional_day15313.5759
GSM1296048V_lesional_day151164.0382
GSM1296059A_lesional_day43893.577
GSM1296066G_lesional_day431850.7188
GSM1296060R_lesional_day43440.9965
GSM1296063U_lesional_day43544.6169
GSM1296064E_lesional_day43870.1777
GSM1296067H_lesional_day43471.5666
GSM1296062M_lesional_day43310.3859
GSM1296068Q_lesional_day43519.7968
GSM1296050C_lesional_day43189.6652
GSM1296057D_lesional_day43216.8354
GSM1296052I_lesional_day4388.6341
GSM1296054J_lesional_day43261.5456
GSM1296049K_lesional_day43236.5955
GSM1296055W_lesional_day43231.1954
GSM1296053X_lesional_day43223.0454
GSM1296058Z_lesional_day43279.0958
GSM1296051F_lesional_day43305.3960
GSM1296056O_lesional_day43385.2664
GSM1296065S_lesional_day43368.6162
GSM1296061T_lesional_day43383.1562
GSM1296095A_non-lesional_pre-dose691.8273
GSM1296120B_non-lesional_pre-dose737.9474
GSM1296077C_non-lesional_pre-dose282.859
GSM1296093D_non-lesional_pre-dose365.3162
GSM1296104E_non-lesional_pre-dose425.365
GSM1296079F_non-lesional_pre-dose291.0159
GSM1296108G_non-lesional_pre-dose787.3675
GSM1296110H_non-lesional_pre-dose993.5179
GSM1296081I_non-lesional_pre-dose291.3159
GSM1296091J_non-lesional_pre-dose253.6757
GSM1296075K_non-lesional_pre-dose330.0862
GSM1296112L_non-lesional_pre-dose630.7871
GSM1296100M_non-lesional_pre-dose394.9163
GSM1296087O_non-lesional_pre-dose76.6640
GSM1296118P_non-lesional_pre-dose718.5974
GSM1296114Q_non-lesional_pre-dose1014.5680
GSM1296097R_non-lesional_pre-dose349.4662
GSM1296106S_non-lesional_pre-dose355.361
GSM1296102U_non-lesional_pre-dose243.6354
GSM1296122V_non-lesional_pre-dose406.3364
GSM1296089W_non-lesional_pre-dose300.8658
GSM1296083X_non-lesional_pre-dose303.5259
GSM1296116Y_non-lesional_pre-dose885.9977
GSM1296085Z_non-lesional_pre-dose281.5258