ProfileGDS5420 / 242239_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 41% 39% 39% 34% 33% 35% 38% 38% 43% 36% 29% 37% 25% 32% 42% 44% 36% 41% 41% 38% 31% 38% 37% 37% 39% 41% 37% 46% 41% 32% 49% 40% 35% 34% 40% 31% 43% 42% 45% 41% 48% 43% 45% 42% 44% 51% 44% 45% 43% 44% 35% 43% 42% 45% 37% 38% 43% 35% 38% 31% 44% 44% 46% 49% 39% 47% 57% 44% 39% 45% 36% 37% 28% 37% 42% 40% 42% 50% 52% 17% 43% 48% 45% 52% 44% 40% 46% 48% 52% 52% 48% 41% 39% 49% 48% 43% 51% 46% 47% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose98.941
GSM1296119B_lesional_pre-dose96.5539
GSM1296076C_lesional_pre-dose81.8639
GSM1296092D_lesional_pre-dose51.8434
GSM1296103E_lesional_pre-dose55.0533
GSM1296078F_lesional_pre-dose61.8235
GSM1296107G_lesional_pre-dose91.4638
GSM1296109H_lesional_pre-dose88.6238
GSM1296080I_lesional_pre-dose101.0343
GSM1296090J_lesional_pre-dose64.8136
GSM1296074K_lesional_pre-dose38.9529
GSM1296111L_lesional_pre-dose87.7237
GSM1296099M_lesional_pre-dose33.0125
GSM1296086O_lesional_pre-dose48.8232
GSM1296117P_lesional_pre-dose119.942
GSM1296113Q_lesional_pre-dose139.7544
GSM1296096R_lesional_pre-dose68.8136
GSM1296105S_lesional_pre-dose100.8641
GSM1296098T_lesional_pre-dose102.1341
GSM1296101U_lesional_pre-dose83.638
GSM1296121V_lesional_pre-dose56.231
GSM1296088W_lesional_pre-dose74.4338
GSM1296082X_lesional_pre-dose68.0737
GSM1296115Y_lesional_pre-dose81.1137
GSM1296084Z_lesional_pre-dose84.5339
GSM1296072B_lesional_day8106.641
GSM1296069L_lesional_day891.7837
GSM1296071P_lesional_day8155.0546
GSM1296070Y_lesional_day8115.5241
GSM1296073V_lesional_day858.332
GSM1296034A_lesional_day15178.5149
GSM1296041G_lesional_day15102.4140
GSM1296035R_lesional_day1559.1135
GSM1296038U_lesional_day1561.6534
GSM1296047B_lesional_day15104.0540
GSM1296039E_lesional_day1550.3431
GSM1296042H_lesional_day15129.3643
GSM1296043L_lesional_day15122.6442
GSM1296037M_lesional_day15133.4645
GSM1296046P_lesional_day15113.2741
GSM1296044Q_lesional_day15171.6348
GSM1296045Y_lesional_day15136.4743
GSM1296025C_lesional_day15122.645
GSM1296033D_lesional_day159842
GSM1296027I_lesional_day15105.1644
GSM1296032J_lesional_day15181.4651
GSM1296024K_lesional_day15111.5144
GSM1296031W_lesional_day15131.4945
GSM1296028X_lesional_day15111.1543
GSM1296029Z_lesional_day15119.1244
GSM1296026F_lesional_day1565.635
GSM1296030O_lesional_day1590.5443
GSM1296040S_lesional_day15105.1542
GSM1296036T_lesional_day15135.1745
GSM1296048V_lesional_day1581.5137
GSM1296059A_lesional_day4373.1538
GSM1296066G_lesional_day43128.3743
GSM1296060R_lesional_day4363.1235
GSM1296063U_lesional_day4383.5238
GSM1296064E_lesional_day4347.8631
GSM1296067H_lesional_day43135.0344
GSM1296062M_lesional_day43121.2744
GSM1296068Q_lesional_day43164.1446
GSM1296050C_lesional_day43163.0849
GSM1296057D_lesional_day4384.7739
GSM1296052I_lesional_day43128.9247
GSM1296054J_lesional_day43281.3157
GSM1296049K_lesional_day43112.6144
GSM1296055W_lesional_day4394.8239
GSM1296053X_lesional_day43126.845
GSM1296058Z_lesional_day4364.2136
GSM1296051F_lesional_day4373.9637
GSM1296056O_lesional_day4336.6128
GSM1296065S_lesional_day4377.3337
GSM1296061T_lesional_day43107.2542
GSM1296095A_non-lesional_pre-dose88.9840
GSM1296120B_non-lesional_pre-dose120.9742
GSM1296077C_non-lesional_pre-dose163.0250
GSM1296093D_non-lesional_pre-dose204.2652
GSM1296104E_non-lesional_pre-dose21.6617
GSM1296079F_non-lesional_pre-dose106.4943
GSM1296108G_non-lesional_pre-dose160.8848
GSM1296110H_non-lesional_pre-dose149.7845
GSM1296081I_non-lesional_pre-dose176.6552
GSM1296091J_non-lesional_pre-dose107.9644
GSM1296075K_non-lesional_pre-dose85.9640
GSM1296112L_non-lesional_pre-dose158.3246
GSM1296100M_non-lesional_pre-dose163.7448
GSM1296087O_non-lesional_pre-dose168.5952
GSM1296118P_non-lesional_pre-dose217.6752
GSM1296114Q_non-lesional_pre-dose171.1548
GSM1296097R_non-lesional_pre-dose98.841
GSM1296106S_non-lesional_pre-dose96.7239
GSM1296102U_non-lesional_pre-dose180.9149
GSM1296122V_non-lesional_pre-dose165.2748
GSM1296089W_non-lesional_pre-dose121.0643
GSM1296083X_non-lesional_pre-dose182.1151
GSM1296116Y_non-lesional_pre-dose162.346
GSM1296085Z_non-lesional_pre-dose140.0747