ProfileGDS5420 / 241445_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 68% 54% 54% 50% 64% 52% 55% 55% 59% 47% 49% 53% 58% 49% 56% 59% 57% 61% 73% 66% 58% 53% 50% 57% 58% 54% 58% 57% 56% 54% 73% 53% 56% 61% 57% 56% 51% 58% 52% 60% 62% 54% 60% 49% 43% 57% 62% 56% 57% 52% 53% 51% 58% 75% 62% 60% 57% 57% 58% 58% 49% 61% 56% 53% 50% 49% 58% 60% 56% 50% 42% 54% 54% 49% 73% 63% 55% 55% 58% 62% 59% 57% 57% 44% 47% 54% 59% 55% 48% 62% 59% 57% 61% 63% 57% 56% 60% 59% 53% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose540.168
GSM1296119B_lesional_pre-dose222.8154
GSM1296076C_lesional_pre-dose203.7254
GSM1296092D_lesional_pre-dose152.1950
GSM1296103E_lesional_pre-dose402.1164
GSM1296078F_lesional_pre-dose170.0452
GSM1296107G_lesional_pre-dose239.6355
GSM1296109H_lesional_pre-dose247.4855
GSM1296080I_lesional_pre-dose291.3159
GSM1296090J_lesional_pre-dose134.6947
GSM1296074K_lesional_pre-dose141.3249
GSM1296111L_lesional_pre-dose222.853
GSM1296099M_lesional_pre-dose295.758
GSM1296086O_lesional_pre-dose153.0249
GSM1296117P_lesional_pre-dose255.5156
GSM1296113Q_lesional_pre-dose314.5959
GSM1296096R_lesional_pre-dose257.3157
GSM1296105S_lesional_pre-dose343.5861
GSM1296098T_lesional_pre-dose706.4573
GSM1296101U_lesional_pre-dose464.966
GSM1296121V_lesional_pre-dose279.658
GSM1296088W_lesional_pre-dose204.953
GSM1296082X_lesional_pre-dose159.1750
GSM1296115Y_lesional_pre-dose267.8657
GSM1296084Z_lesional_pre-dose276.6658
GSM1296072B_lesional_day8227.9154
GSM1296069L_lesional_day8296.2858
GSM1296071P_lesional_day8285.6357
GSM1296070Y_lesional_day8263.5556
GSM1296073V_lesional_day8214.8454
GSM1296034A_lesional_day15704.3573
GSM1296041G_lesional_day15217.0353
GSM1296035R_lesional_day15247.5556
GSM1296038U_lesional_day15346.6261
GSM1296047B_lesional_day15283.6557
GSM1296039E_lesional_day15248.1256
GSM1296042H_lesional_day15201.9751
GSM1296043L_lesional_day15292.1158
GSM1296037M_lesional_day15200.2152
GSM1296046P_lesional_day15329.260
GSM1296044Q_lesional_day15379.1262
GSM1296045Y_lesional_day15239.6454
GSM1296025C_lesional_day15303.160
GSM1296033D_lesional_day15159.949
GSM1296027I_lesional_day1593.843
GSM1296032J_lesional_day15269.4457
GSM1296024K_lesional_day15352.2362
GSM1296031W_lesional_day15263.8556
GSM1296028X_lesional_day15266.9157
GSM1296029Z_lesional_day15195.0252
GSM1296026F_lesional_day15203.9453
GSM1296030O_lesional_day15162.8451
GSM1296040S_lesional_day15289.4858
GSM1296036T_lesional_day15784.4475
GSM1296048V_lesional_day15351.9562
GSM1296059A_lesional_day43319.9360
GSM1296066G_lesional_day43276.8457
GSM1296060R_lesional_day43263.5857
GSM1296063U_lesional_day43277.5658
GSM1296064E_lesional_day43279.0558
GSM1296067H_lesional_day43179.6349
GSM1296062M_lesional_day43356.9461
GSM1296068Q_lesional_day43281.956
GSM1296050C_lesional_day43206.4453
GSM1296057D_lesional_day43174.350
GSM1296052I_lesional_day43144.249
GSM1296054J_lesional_day43298.2458
GSM1296049K_lesional_day43310.2160
GSM1296055W_lesional_day43267.7856
GSM1296053X_lesional_day43178.8350
GSM1296058Z_lesional_day4397.2642
GSM1296051F_lesional_day43202.1854
GSM1296056O_lesional_day43206.4254
GSM1296065S_lesional_day43165.1949
GSM1296061T_lesional_day4370873
GSM1296095A_non-lesional_pre-dose363.0863
GSM1296120B_non-lesional_pre-dose253.1655
GSM1296077C_non-lesional_pre-dose226.0455
GSM1296093D_non-lesional_pre-dose298.5158
GSM1296104E_non-lesional_pre-dose357.2162
GSM1296079F_non-lesional_pre-dose281.6659
GSM1296108G_non-lesional_pre-dose273.7557
GSM1296110H_non-lesional_pre-dose288.4557
GSM1296081I_non-lesional_pre-dose107.344
GSM1296091J_non-lesional_pre-dose132.7247
GSM1296075K_non-lesional_pre-dose202.3554
GSM1296112L_non-lesional_pre-dose329.8959
GSM1296100M_non-lesional_pre-dose251.7355
GSM1296087O_non-lesional_pre-dose133.0148
GSM1296118P_non-lesional_pre-dose370.1462
GSM1296114Q_non-lesional_pre-dose324.0259
GSM1296097R_non-lesional_pre-dose263.2957
GSM1296106S_non-lesional_pre-dose343.7361
GSM1296102U_non-lesional_pre-dose405.2663
GSM1296122V_non-lesional_pre-dose271.5257
GSM1296089W_non-lesional_pre-dose258.4856
GSM1296083X_non-lesional_pre-dose329.6660
GSM1296116Y_non-lesional_pre-dose318.9459
GSM1296085Z_non-lesional_pre-dose210.853