ProfileGDS5420 / 240913_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 67% 61% 49% 46% 67% 50% 59% 56% 60% 46% 49% 62% 56% 48% 58% 61% 56% 63% 75% 62% 63% 62% 47% 61% 59% 66% 55% 55% 62% 53% 72% 62% 51% 60% 66% 57% 60% 58% 58% 67% 68% 62% 59% 45% 48% 52% 62% 61% 57% 47% 48% 42% 70% 74% 54% 50% 55% 56% 57% 61% 61% 60% 67% 56% 55% 50% 64% 57% 58% 55% 50% 45% 49% 63% 72% 61% 63% 60% 50% 55% 49% 62% 65% 57% 51% 47% 58% 66% 42% 60% 68% 57% 70% 64% 50% 71% 54% 63% 51% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose488.3767
GSM1296119B_lesional_pre-dose338.9561
GSM1296076C_lesional_pre-dose147.9749
GSM1296092D_lesional_pre-dose113.7946
GSM1296103E_lesional_pre-dose496.1367
GSM1296078F_lesional_pre-dose157.5350
GSM1296107G_lesional_pre-dose307.5359
GSM1296109H_lesional_pre-dose263.3656
GSM1296080I_lesional_pre-dose310.6760
GSM1296090J_lesional_pre-dose123.9346
GSM1296074K_lesional_pre-dose139.749
GSM1296111L_lesional_pre-dose359.6962
GSM1296099M_lesional_pre-dose262.0656
GSM1296086O_lesional_pre-dose135.3848
GSM1296117P_lesional_pre-dose285.7158
GSM1296113Q_lesional_pre-dose352.4761
GSM1296096R_lesional_pre-dose241.556
GSM1296105S_lesional_pre-dose395.563
GSM1296098T_lesional_pre-dose765.975
GSM1296101U_lesional_pre-dose377.2262
GSM1296121V_lesional_pre-dose386.8163
GSM1296088W_lesional_pre-dose358.8562
GSM1296082X_lesional_pre-dose125.4847
GSM1296115Y_lesional_pre-dose350.2261
GSM1296084Z_lesional_pre-dose301.9759
GSM1296072B_lesional_day8468.9466
GSM1296069L_lesional_day8255.8155
GSM1296071P_lesional_day8256.955
GSM1296070Y_lesional_day8375.3362
GSM1296073V_lesional_day8206.953
GSM1296034A_lesional_day15660.1972
GSM1296041G_lesional_day15359.4562
GSM1296035R_lesional_day15180.7851
GSM1296038U_lesional_day15320.6360
GSM1296047B_lesional_day15472.2466
GSM1296039E_lesional_day15256.6657
GSM1296042H_lesional_day15320.4260
GSM1296043L_lesional_day15307.5358
GSM1296037M_lesional_day15283.2758
GSM1296046P_lesional_day15507.8767
GSM1296044Q_lesional_day15524.4468
GSM1296045Y_lesional_day15369.4762
GSM1296025C_lesional_day15299.659
GSM1296033D_lesional_day15125.7245
GSM1296027I_lesional_day15138.8648
GSM1296032J_lesional_day15201.9752
GSM1296024K_lesional_day15342.5862
GSM1296031W_lesional_day15352.5461
GSM1296028X_lesional_day15258.4957
GSM1296029Z_lesional_day15142.4147
GSM1296026F_lesional_day15142.1748
GSM1296030O_lesional_day1588.5342
GSM1296040S_lesional_day15588.3570
GSM1296036T_lesional_day15755.6474
GSM1296048V_lesional_day15219.3254
GSM1296059A_lesional_day43168.4150
GSM1296066G_lesional_day43249.2555
GSM1296060R_lesional_day43249.3156
GSM1296063U_lesional_day43272.357
GSM1296064E_lesional_day43319.7261
GSM1296067H_lesional_day43356.8661
GSM1296062M_lesional_day43333.5760
GSM1296068Q_lesional_day43486.9767
GSM1296050C_lesional_day43240.3756
GSM1296057D_lesional_day43231.6855
GSM1296052I_lesional_day43160.0650
GSM1296054J_lesional_day43410.5764
GSM1296049K_lesional_day43256.3157
GSM1296055W_lesional_day43284.9758
GSM1296053X_lesional_day43237.0155
GSM1296058Z_lesional_day43162.1750
GSM1296051F_lesional_day43121.9145
GSM1296056O_lesional_day43152.3349
GSM1296065S_lesional_day43392.4663
GSM1296061T_lesional_day43684.0772
GSM1296095A_non-lesional_pre-dose331.6161
GSM1296120B_non-lesional_pre-dose388.6263
GSM1296077C_non-lesional_pre-dose303.660
GSM1296093D_non-lesional_pre-dose188.3150
GSM1296104E_non-lesional_pre-dose235.3855
GSM1296079F_non-lesional_pre-dose157.7349
GSM1296108G_non-lesional_pre-dose370.2862
GSM1296110H_non-lesional_pre-dose450.165
GSM1296081I_non-lesional_pre-dose249.2357
GSM1296091J_non-lesional_pre-dose169.9451
GSM1296075K_non-lesional_pre-dose130.0947
GSM1296112L_non-lesional_pre-dose307.0358
GSM1296100M_non-lesional_pre-dose468.1966
GSM1296087O_non-lesional_pre-dose91.2242
GSM1296118P_non-lesional_pre-dose339.4860
GSM1296114Q_non-lesional_pre-dose515.0868
GSM1296097R_non-lesional_pre-dose267.4757
GSM1296106S_non-lesional_pre-dose575.5770
GSM1296102U_non-lesional_pre-dose428.564
GSM1296122V_non-lesional_pre-dose190.8150
GSM1296089W_non-lesional_pre-dose625.1271
GSM1296083X_non-lesional_pre-dose224.7954
GSM1296116Y_non-lesional_pre-dose387.8863
GSM1296085Z_non-lesional_pre-dose178.6651