ProfileGDS5420 / 240128_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 76% 74% 67% 62% 78% 64% 74% 76% 66% 63% 67% 71% 73% 61% 72% 79% 73% 70% 82% 80% 75% 70% 66% 73% 70% 75% 73% 74% 75% 75% 83% 72% 73% 73% 75% 72% 74% 74% 73% 74% 77% 75% 61% 67% 61% 66% 66% 71% 64% 68% 61% 63% 74% 83% 76% 76% 75% 73% 72% 73% 75% 77% 74% 62% 70% 63% 70% 68% 70% 72% 72% 64% 69% 71% 81% 74% 75% 59% 70% 70% 59% 74% 78% 60% 61% 66% 75% 70% 60% 74% 80% 68% 75% 77% 71% 70% 62% 76% 63% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose848.3676
GSM1296119B_lesional_pre-dose716.0374
GSM1296076C_lesional_pre-dose451.9867
GSM1296092D_lesional_pre-dose344.9662
GSM1296103E_lesional_pre-dose948.6578
GSM1296078F_lesional_pre-dose371.7464
GSM1296107G_lesional_pre-dose699.474
GSM1296109H_lesional_pre-dose799.5876
GSM1296080I_lesional_pre-dose449.9566
GSM1296090J_lesional_pre-dose355.5963
GSM1296074K_lesional_pre-dose440.7467
GSM1296111L_lesional_pre-dose602.9171
GSM1296099M_lesional_pre-dose694.973
GSM1296086O_lesional_pre-dose327.361
GSM1296117P_lesional_pre-dose634.8472
GSM1296113Q_lesional_pre-dose970.5879
GSM1296096R_lesional_pre-dose696.4273
GSM1296105S_lesional_pre-dose596.9770
GSM1296098T_lesional_pre-dose1180.0982
GSM1296101U_lesional_pre-dose1065.4980
GSM1296121V_lesional_pre-dose752.3375
GSM1296088W_lesional_pre-dose577.6570
GSM1296082X_lesional_pre-dose438.3766
GSM1296115Y_lesional_pre-dose699.873
GSM1296084Z_lesional_pre-dose559.5970
GSM1296072B_lesional_day8769.7375
GSM1296069L_lesional_day8684.1673
GSM1296071P_lesional_day8718.4674
GSM1296070Y_lesional_day8750.9275
GSM1296073V_lesional_day8782.5275
GSM1296034A_lesional_day151235.683
GSM1296041G_lesional_day15641.6872
GSM1296035R_lesional_day15712.1373
GSM1296038U_lesional_day15676.5473
GSM1296047B_lesional_day15785.0775
GSM1296039E_lesional_day15614.1272
GSM1296042H_lesional_day15739.2674
GSM1296043L_lesional_day15742.7374
GSM1296037M_lesional_day15707.5873
GSM1296046P_lesional_day15742.9674
GSM1296044Q_lesional_day15883.4877
GSM1296045Y_lesional_day15781.8475
GSM1296025C_lesional_day15326.1561
GSM1296033D_lesional_day15488.8767
GSM1296027I_lesional_day15327.5161
GSM1296032J_lesional_day15474.5866
GSM1296024K_lesional_day15437.466
GSM1296031W_lesional_day15623.6371
GSM1296028X_lesional_day15402.5864
GSM1296029Z_lesional_day15508.4668
GSM1296026F_lesional_day15317.7561
GSM1296030O_lesional_day15372.0963
GSM1296040S_lesional_day15763.4174
GSM1296036T_lesional_day151269.7883
GSM1296048V_lesional_day15794.2576
GSM1296059A_lesional_day43813.5276
GSM1296066G_lesional_day43765.7575
GSM1296060R_lesional_day43692.773
GSM1296063U_lesional_day43652.3772
GSM1296064E_lesional_day43688.773
GSM1296067H_lesional_day43797.7375
GSM1296062M_lesional_day43899.377
GSM1296068Q_lesional_day43739.6574
GSM1296050C_lesional_day43355.662
GSM1296057D_lesional_day43586.2970
GSM1296052I_lesional_day43366.2763
GSM1296054J_lesional_day43576.5470
GSM1296049K_lesional_day43522.7468
GSM1296055W_lesional_day43585.7870
GSM1296053X_lesional_day43668.2172
GSM1296058Z_lesional_day43668.2772
GSM1296051F_lesional_day43393.3764
GSM1296056O_lesional_day43526.8669
GSM1296065S_lesional_day43601.0471
GSM1296061T_lesional_day431158.4481
GSM1296095A_non-lesional_pre-dose736.8174
GSM1296120B_non-lesional_pre-dose747.8575
GSM1296077C_non-lesional_pre-dose284.1259
GSM1296093D_non-lesional_pre-dose582.0470
GSM1296104E_non-lesional_pre-dose576.6770
GSM1296079F_non-lesional_pre-dose279.0559
GSM1296108G_non-lesional_pre-dose730.5674
GSM1296110H_non-lesional_pre-dose898.4478
GSM1296081I_non-lesional_pre-dose314.4960
GSM1296091J_non-lesional_pre-dose320.5361
GSM1296075K_non-lesional_pre-dose441.266
GSM1296112L_non-lesional_pre-dose787.0575
GSM1296100M_non-lesional_pre-dose583.1970
GSM1296087O_non-lesional_pre-dose299.9160
GSM1296118P_non-lesional_pre-dose733.974
GSM1296114Q_non-lesional_pre-dose1011.4180
GSM1296097R_non-lesional_pre-dose506.3268
GSM1296106S_non-lesional_pre-dose777.8575
GSM1296102U_non-lesional_pre-dose881.3577
GSM1296122V_non-lesional_pre-dose617.3171
GSM1296089W_non-lesional_pre-dose591.970
GSM1296083X_non-lesional_pre-dose362.8462
GSM1296116Y_non-lesional_pre-dose800.4576
GSM1296085Z_non-lesional_pre-dose395.0863