ProfileGDS5420 / 239979_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 65% 74% 46% 63% 72% 54% 60% 61% 61% 58% 64% 58% 68% 49% 71% 91% 51% 61% 82% 75% 54% 58% 51% 67% 44% 65% 59% 60% 62% 58% 56% 62% 60% 63% 64% 81% 61% 50% 54% 63% 71% 61% 39% 57% 60% 48% 53% 62% 28% 43% 52% 50% 62% 81% 59% 57% 59% 53% 67% 68% 60% 60% 61% 39% 50% 56% 53% 53% 62% 35% 37% 43% 54% 52% 84% 44% 60% 31% 49% 58% 31% 59% 54% 46% 35% 36% 38% 49% 36% 40% 91% 33% 55% 76% 54% 50% 37% 46% 27% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose450.8365
GSM1296119B_lesional_pre-dose731.2274
GSM1296076C_lesional_pre-dose122.8346
GSM1296092D_lesional_pre-dose368.2863
GSM1296103E_lesional_pre-dose651.8172
GSM1296078F_lesional_pre-dose199.8854
GSM1296107G_lesional_pre-dose327.2260
GSM1296109H_lesional_pre-dose357.7461
GSM1296080I_lesional_pre-dose334.5461
GSM1296090J_lesional_pre-dose269.0158
GSM1296074K_lesional_pre-dose373.3364
GSM1296111L_lesional_pre-dose282.0858
GSM1296099M_lesional_pre-dose512.6168
GSM1296086O_lesional_pre-dose151.0949
GSM1296117P_lesional_pre-dose610.6571
GSM1296113Q_lesional_pre-dose2160.2591
GSM1296096R_lesional_pre-dose183.1551
GSM1296105S_lesional_pre-dose344.8361
GSM1296098T_lesional_pre-dose1158.682
GSM1296101U_lesional_pre-dose772.3175
GSM1296121V_lesional_pre-dose223.0754
GSM1296088W_lesional_pre-dose272.4558
GSM1296082X_lesional_pre-dose164.9951
GSM1296115Y_lesional_pre-dose474.1367
GSM1296084Z_lesional_pre-dose120.544
GSM1296072B_lesional_day8420.1865
GSM1296069L_lesional_day8318.3959
GSM1296071P_lesional_day8334.6760
GSM1296070Y_lesional_day8376.6462
GSM1296073V_lesional_day8275.6558
GSM1296034A_lesional_day15272.0556
GSM1296041G_lesional_day15361.4962
GSM1296035R_lesional_day15322.6160
GSM1296038U_lesional_day15388.6163
GSM1296047B_lesional_day15408.9864
GSM1296039E_lesional_day151117.0981
GSM1296042H_lesional_day15340.9661
GSM1296043L_lesional_day15193.650
GSM1296037M_lesional_day15231.1854
GSM1296046P_lesional_day15390.1163
GSM1296044Q_lesional_day15601.2471
GSM1296045Y_lesional_day15352.5761
GSM1296025C_lesional_day1583.7839
GSM1296033D_lesional_day15269.0457
GSM1296027I_lesional_day15306.1360
GSM1296032J_lesional_day15150.9348
GSM1296024K_lesional_day15201.1953
GSM1296031W_lesional_day15377.962
GSM1296028X_lesional_day1539.4728
GSM1296029Z_lesional_day15110.3143
GSM1296026F_lesional_day15180.352
GSM1296030O_lesional_day15155.8950
GSM1296040S_lesional_day15363.3162
GSM1296036T_lesional_day151091.7481
GSM1296048V_lesional_day15298.9159
GSM1296059A_lesional_day43261.6257
GSM1296066G_lesional_day43312.8659
GSM1296060R_lesional_day43206.3653
GSM1296063U_lesional_day43479.1667
GSM1296064E_lesional_day43495.4768
GSM1296067H_lesional_day43342.9460
GSM1296062M_lesional_day43331.1960
GSM1296068Q_lesional_day43355.0261
GSM1296050C_lesional_day4384.8339
GSM1296057D_lesional_day43173.9450
GSM1296052I_lesional_day43237.4856
GSM1296054J_lesional_day43211.3753
GSM1296049K_lesional_day43211.5353
GSM1296055W_lesional_day43359.7562
GSM1296053X_lesional_day4366.3235
GSM1296058Z_lesional_day4368.5137
GSM1296051F_lesional_day43102.343
GSM1296056O_lesional_day43213.3654
GSM1296065S_lesional_day43199.5852
GSM1296061T_lesional_day431370.8884
GSM1296095A_non-lesional_pre-dose114.0844
GSM1296120B_non-lesional_pre-dose323.2460
GSM1296077C_non-lesional_pre-dose46.2531
GSM1296093D_non-lesional_pre-dose168.0449
GSM1296104E_non-lesional_pre-dose283.858
GSM1296079F_non-lesional_pre-dose51.0631
GSM1296108G_non-lesional_pre-dose313.0959
GSM1296110H_non-lesional_pre-dose251.5354
GSM1296081I_non-lesional_pre-dose122.0246
GSM1296091J_non-lesional_pre-dose60.135
GSM1296075K_non-lesional_pre-dose68.2936
GSM1296112L_non-lesional_pre-dose100.8638
GSM1296100M_non-lesional_pre-dose170.9849
GSM1296087O_non-lesional_pre-dose59.8636
GSM1296118P_non-lesional_pre-dose109.6540
GSM1296114Q_non-lesional_pre-dose2275.9491
GSM1296097R_non-lesional_pre-dose54.9933
GSM1296106S_non-lesional_pre-dose248.6855
GSM1296102U_non-lesional_pre-dose812.5276
GSM1296122V_non-lesional_pre-dose232.0454
GSM1296089W_non-lesional_pre-dose183.2750
GSM1296083X_non-lesional_pre-dose74.6437
GSM1296116Y_non-lesional_pre-dose158.146
GSM1296085Z_non-lesional_pre-dose38.2727