ProfileGDS5420 / 239118_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 30% 25% 34% 31% 32% 32% 40% 15% 31% 28% 24% 35% 40% 28% 31% 22% 36% 47% 32% 47% 27% 37% 36% 27% 38% 23% 29% 33% 34% 31% 37% 34% 35% 40% 22% 37% 22% 28% 36% 29% 33% 36% 45% 40% 37% 36% 39% 43% 41% 32% 27% 40% 36% 24% 28% 26% 37% 36% 51% 33% 31% 37% 39% 51% 30% 35% 29% 35% 38% 39% 38% 37% 38% 51% 41% 32% 39% 46% 52% 32% 30% 41% 27% 51% 33% 38% 33% 46% 45% 30% 15% 42% 42% 51% 47% 36% 46% 32% 31% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
Graph caption help
SampleTitleValueRank
GSM1296094A_lesional_pre-dose44.4230
GSM1296119B_lesional_pre-dose38.6325
GSM1296076C_lesional_pre-dose59.0234
GSM1296092D_lesional_pre-dose43.8831
GSM1296103E_lesional_pre-dose50.9132
GSM1296078F_lesional_pre-dose53.9632
GSM1296107G_lesional_pre-dose102.3440
GSM1296109H_lesional_pre-dose19.215
GSM1296080I_lesional_pre-dose44.2331
GSM1296090J_lesional_pre-dose36.9428
GSM1296074K_lesional_pre-dose26.9624
GSM1296111L_lesional_pre-dose77.6735
GSM1296099M_lesional_pre-dose92.1940
GSM1296086O_lesional_pre-dose37.4628
GSM1296117P_lesional_pre-dose60.9831
GSM1296113Q_lesional_pre-dose38.2322
GSM1296096R_lesional_pre-dose65.1236
GSM1296105S_lesional_pre-dose150.6947
GSM1296098T_lesional_pre-dose62.3932
GSM1296101U_lesional_pre-dose147.9447
GSM1296121V_lesional_pre-dose43.3627
GSM1296088W_lesional_pre-dose73.0637
GSM1296082X_lesional_pre-dose61.1736
GSM1296115Y_lesional_pre-dose44.9127
GSM1296084Z_lesional_pre-dose83.0938
GSM1296072B_lesional_day832.4223
GSM1296069L_lesional_day856.1629
GSM1296071P_lesional_day873.933
GSM1296070Y_lesional_day875.5534
GSM1296073V_lesional_day855.8531
GSM1296034A_lesional_day1578.8937
GSM1296041G_lesional_day1570.8934
GSM1296035R_lesional_day1558.7635
GSM1296038U_lesional_day1592.8740
GSM1296047B_lesional_day1534.6222
GSM1296039E_lesional_day1571.9637
GSM1296042H_lesional_day1535.5222
GSM1296043L_lesional_day1554.0128
GSM1296037M_lesional_day1575.0336
GSM1296046P_lesional_day1557.2429
GSM1296044Q_lesional_day1568.6833
GSM1296045Y_lesional_day1590.7636
GSM1296025C_lesional_day15126.1845
GSM1296033D_lesional_day1589.2840
GSM1296027I_lesional_day1562.3237
GSM1296032J_lesional_day1568.1536
GSM1296024K_lesional_day1578.8539
GSM1296031W_lesional_day15114.3143
GSM1296028X_lesional_day1594.4441
GSM1296029Z_lesional_day1551.3932
GSM1296026F_lesional_day1538.8327
GSM1296030O_lesional_day1574.8240
GSM1296040S_lesional_day1573.236
GSM1296036T_lesional_day1534.5724
GSM1296048V_lesional_day1547.5128
GSM1296059A_lesional_day4332.0526
GSM1296066G_lesional_day4388.5637
GSM1296060R_lesional_day4369.6636
GSM1296063U_lesional_day43187.0851
GSM1296064E_lesional_day4354.3733
GSM1296067H_lesional_day4361.3431
GSM1296062M_lesional_day4375.8337
GSM1296068Q_lesional_day43106.6139
GSM1296050C_lesional_day43183.651
GSM1296057D_lesional_day4345.1430
GSM1296052I_lesional_day4358.7235
GSM1296054J_lesional_day4345.0329
GSM1296049K_lesional_day436535
GSM1296055W_lesional_day4384.9638
GSM1296053X_lesional_day4385.9339
GSM1296058Z_lesional_day4375.5138
GSM1296051F_lesional_day4373.0937
GSM1296056O_lesional_day4374.0238
GSM1296065S_lesional_day43185.0551
GSM1296061T_lesional_day43103.6641
GSM1296095A_non-lesional_pre-dose52.3832
GSM1296120B_non-lesional_pre-dose97.6739
GSM1296077C_non-lesional_pre-dose123.5846
GSM1296093D_non-lesional_pre-dose205.5452
GSM1296104E_non-lesional_pre-dose53.6632
GSM1296079F_non-lesional_pre-dose46.8530
GSM1296108G_non-lesional_pre-dose109.8841
GSM1296110H_non-lesional_pre-dose48.2527
GSM1296081I_non-lesional_pre-dose167.8651
GSM1296091J_non-lesional_pre-dose55.3833
GSM1296075K_non-lesional_pre-dose75.4838
GSM1296112L_non-lesional_pre-dose78.933
GSM1296100M_non-lesional_pre-dose146.3446
GSM1296087O_non-lesional_pre-dose110.4545
GSM1296118P_non-lesional_pre-dose58.9630
GSM1296114Q_non-lesional_pre-dose20.6115
GSM1296097R_non-lesional_pre-dose102.6342
GSM1296106S_non-lesional_pre-dose116.5942
GSM1296102U_non-lesional_pre-dose196.6851
GSM1296122V_non-lesional_pre-dose157.9347
GSM1296089W_non-lesional_pre-dose76.7936
GSM1296083X_non-lesional_pre-dose133.8946
GSM1296116Y_non-lesional_pre-dose71.3132
GSM1296085Z_non-lesional_pre-dose52.2631