ProfileGDS5420 / 238987_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 55% 45% 43% 49% 56% 40% 46% 49% 47% 51% 52% 48% 55% 48% 50% 53% 51% 52% 57% 50% 48% 46% 45% 47% 50% 49% 54% 53% 48% 48% 59% 49% 53% 49% 55% 45% 49% 54% 59% 51% 54% 48% 34% 45% 46% 47% 46% 53% 42% 54% 35% 41% 51% 55% 53% 55% 46% 50% 55% 60% 48% 57% 53% 42% 55% 47% 51% 46% 59% 46% 52% 47% 49% 47% 56% 58% 46% 32% 48% 59% 37% 48% 49% 38% 45% 38% 49% 50% 42% 51% 60% 49% 51% 50% 47% 48% 42% 50% 48% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose236.2755
GSM1296119B_lesional_pre-dose137.2345
GSM1296076C_lesional_pre-dose103.443
GSM1296092D_lesional_pre-dose146.9249
GSM1296103E_lesional_pre-dose243.3356
GSM1296078F_lesional_pre-dose83.9340
GSM1296107G_lesional_pre-dose143.1746
GSM1296109H_lesional_pre-dose176.4449
GSM1296080I_lesional_pre-dose130.4747
GSM1296090J_lesional_pre-dose174.451
GSM1296074K_lesional_pre-dose168.3152
GSM1296111L_lesional_pre-dose161.4448
GSM1296099M_lesional_pre-dose240.5755
GSM1296086O_lesional_pre-dose136.6148
GSM1296117P_lesional_pre-dose184.2850
GSM1296113Q_lesional_pre-dose224.6253
GSM1296096R_lesional_pre-dose176.3951
GSM1296105S_lesional_pre-dose200.5752
GSM1296098T_lesional_pre-dose265.0657
GSM1296101U_lesional_pre-dose175.5850
GSM1296121V_lesional_pre-dose158.3448
GSM1296088W_lesional_pre-dose128.3446
GSM1296082X_lesional_pre-dose112.8445
GSM1296115Y_lesional_pre-dose149.0847
GSM1296084Z_lesional_pre-dose166.3150
GSM1296072B_lesional_day8176.2249
GSM1296069L_lesional_day8237.2754
GSM1296071P_lesional_day8233.7853
GSM1296070Y_lesional_day8170.1348
GSM1296073V_lesional_day8155.448
GSM1296034A_lesional_day15319.3859
GSM1296041G_lesional_day15164.9449
GSM1296035R_lesional_day15202.6953
GSM1296038U_lesional_day1516349
GSM1296047B_lesional_day15246.7455
GSM1296039E_lesional_day15119.7345
GSM1296042H_lesional_day15173.749
GSM1296043L_lesional_day15240.9954
GSM1296037M_lesional_day15299.1859
GSM1296046P_lesional_day15203.7151
GSM1296044Q_lesional_day15237.454
GSM1296045Y_lesional_day15176.7248
GSM1296025C_lesional_day1560.7834
GSM1296033D_lesional_day15121.2945
GSM1296027I_lesional_day15113.3546
GSM1296032J_lesional_day15144.1247
GSM1296024K_lesional_day15127.0746
GSM1296031W_lesional_day15220.0653
GSM1296028X_lesional_day15103.9142
GSM1296029Z_lesional_day15214.8354
GSM1296026F_lesional_day1566.3635
GSM1296030O_lesional_day1580.3341
GSM1296040S_lesional_day15184.1651
GSM1296036T_lesional_day15247.3555
GSM1296048V_lesional_day15209.0353
GSM1296059A_lesional_day43233.6855
GSM1296066G_lesional_day43151.8146
GSM1296060R_lesional_day43174.1150
GSM1296063U_lesional_day43231.6155
GSM1296064E_lesional_day43307.0660
GSM1296067H_lesional_day43168.1348
GSM1296062M_lesional_day43276.4357
GSM1296068Q_lesional_day43236.4953
GSM1296050C_lesional_day43106.9942
GSM1296057D_lesional_day43239.4555
GSM1296052I_lesional_day43128.6247
GSM1296054J_lesional_day43192.1351
GSM1296049K_lesional_day43131.2546
GSM1296055W_lesional_day43305.7259
GSM1296053X_lesional_day43135.8646
GSM1296058Z_lesional_day43189.5452
GSM1296051F_lesional_day43137.4947
GSM1296056O_lesional_day43147.9749
GSM1296065S_lesional_day43146.5547
GSM1296061T_lesional_day43264.3156
GSM1296095A_non-lesional_pre-dose270.0258
GSM1296120B_non-lesional_pre-dose145.8646
GSM1296077C_non-lesional_pre-dose51.3132
GSM1296093D_non-lesional_pre-dose163.9548
GSM1296104E_non-lesional_pre-dose297.3159
GSM1296079F_non-lesional_pre-dose73.0637
GSM1296108G_non-lesional_pre-dose167.4648
GSM1296110H_non-lesional_pre-dose185.0449
GSM1296081I_non-lesional_pre-dose72.938
GSM1296091J_non-lesional_pre-dose121.6645
GSM1296075K_non-lesional_pre-dose76.5438
GSM1296112L_non-lesional_pre-dose193.0949
GSM1296100M_non-lesional_pre-dose180.9150
GSM1296087O_non-lesional_pre-dose87.9242
GSM1296118P_non-lesional_pre-dose211.7151
GSM1296114Q_non-lesional_pre-dose328.3260
GSM1296097R_non-lesional_pre-dose161.849
GSM1296106S_non-lesional_pre-dose202.5751
GSM1296102U_non-lesional_pre-dose183.5350
GSM1296122V_non-lesional_pre-dose160.7547
GSM1296089W_non-lesional_pre-dose166.0648
GSM1296083X_non-lesional_pre-dose106.3742
GSM1296116Y_non-lesional_pre-dose194.2550
GSM1296085Z_non-lesional_pre-dose156.3348