ProfileGDS5420 / 238864_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 50% 40% 52% 39% 45% 45% 55% 44% 33% 39% 39% 43% 55% 54% 36% 45% 54% 52% 46% 58% 45% 49% 53% 46% 52% 53% 49% 52% 56% 40% 42% 57% 59% 62% 40% 40% 52% 54% 33% 42% 37% 52% 41% 52% 36% 32% 52% 31% 41% 47% 54% 48% 65% 41% 41% 54% 56% 50% 59% 53% 42% 45% 39% 30% 42% 37% 28% 37% 37% 42% 62% 53% 48% 58% 43% 56% 33% 44% 39% 42% 48% 42% 39% 38% 47% 45% 50% 33% 46% 36% 46% 50% 48% 42% 35% 34% 38% 46% 31% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose171.1150
GSM1296119B_lesional_pre-dose100.6640
GSM1296076C_lesional_pre-dose175.0952
GSM1296092D_lesional_pre-dose74.8139
GSM1296103E_lesional_pre-dose124.3645
GSM1296078F_lesional_pre-dose116.445
GSM1296107G_lesional_pre-dose235.5655
GSM1296109H_lesional_pre-dose134.3144
GSM1296080I_lesional_pre-dose50.1933
GSM1296090J_lesional_pre-dose78.3539
GSM1296074K_lesional_pre-dose71.7539
GSM1296111L_lesional_pre-dose123.2343
GSM1296099M_lesional_pre-dose233.2855
GSM1296086O_lesional_pre-dose201.6554
GSM1296117P_lesional_pre-dose81.0636
GSM1296113Q_lesional_pre-dose150.1745
GSM1296096R_lesional_pre-dose216.254
GSM1296105S_lesional_pre-dose200.952
GSM1296098T_lesional_pre-dose137.3146
GSM1296101U_lesional_pre-dose292.6558
GSM1296121V_lesional_pre-dose128.9245
GSM1296088W_lesional_pre-dose150.5649
GSM1296082X_lesional_pre-dose191.2453
GSM1296115Y_lesional_pre-dose144.4246
GSM1296084Z_lesional_pre-dose190.3652
GSM1296072B_lesional_day8218.2753
GSM1296069L_lesional_day8179.4949
GSM1296071P_lesional_day8216.9552
GSM1296070Y_lesional_day8266.2956
GSM1296073V_lesional_day893.2840
GSM1296034A_lesional_day15115.1142
GSM1296041G_lesional_day15273.8557
GSM1296035R_lesional_day15296.4659
GSM1296038U_lesional_day15347.0262
GSM1296047B_lesional_day15107.0240
GSM1296039E_lesional_day1591.4340
GSM1296042H_lesional_day15208.8452
GSM1296043L_lesional_day15245.6354
GSM1296037M_lesional_day1562.3533
GSM1296046P_lesional_day15121.2342
GSM1296044Q_lesional_day1592.3737
GSM1296045Y_lesional_day15218.6152
GSM1296025C_lesional_day1595.0941
GSM1296033D_lesional_day15191.8152
GSM1296027I_lesional_day1558.3736
GSM1296032J_lesional_day1551.9332
GSM1296024K_lesional_day15187.1152
GSM1296031W_lesional_day1551.4331
GSM1296028X_lesional_day1595.1241
GSM1296029Z_lesional_day15137.5247
GSM1296026F_lesional_day15204.654
GSM1296030O_lesional_day15129.5948
GSM1296040S_lesional_day15438.0865
GSM1296036T_lesional_day15104.4841
GSM1296048V_lesional_day15102.6341
GSM1296059A_lesional_day43213.5654
GSM1296066G_lesional_day43259.2456
GSM1296060R_lesional_day43177.9250
GSM1296063U_lesional_day43293.2359
GSM1296064E_lesional_day43195.5753
GSM1296067H_lesional_day43117.7842
GSM1296062M_lesional_day43127.3345
GSM1296068Q_lesional_day43107.8839
GSM1296050C_lesional_day4351.3130
GSM1296057D_lesional_day43101.5942
GSM1296052I_lesional_day4363.4537
GSM1296054J_lesional_day4341.9228
GSM1296049K_lesional_day4376.2637
GSM1296055W_lesional_day4381.8137
GSM1296053X_lesional_day43104.1342
GSM1296058Z_lesional_day43349.8562
GSM1296051F_lesional_day43193.8853
GSM1296056O_lesional_day43137.6448
GSM1296065S_lesional_day43290.9758
GSM1296061T_lesional_day43114.7143
GSM1296095A_non-lesional_pre-dose247.2956
GSM1296120B_non-lesional_pre-dose67.6933
GSM1296077C_non-lesional_pre-dose110.2644
GSM1296093D_non-lesional_pre-dose93.8439
GSM1296104E_non-lesional_pre-dose105.7942
GSM1296079F_non-lesional_pre-dose143.848
GSM1296108G_non-lesional_pre-dose114.3142
GSM1296110H_non-lesional_pre-dose104.7539
GSM1296081I_non-lesional_pre-dose70.6238
GSM1296091J_non-lesional_pre-dose130.1647
GSM1296075K_non-lesional_pre-dose113.2745
GSM1296112L_non-lesional_pre-dose200.4650
GSM1296100M_non-lesional_pre-dose59.7233
GSM1296087O_non-lesional_pre-dose115.7146
GSM1296118P_non-lesional_pre-dose86.4236
GSM1296114Q_non-lesional_pre-dose151.946
GSM1296097R_non-lesional_pre-dose176.2650
GSM1296106S_non-lesional_pre-dose166.1148
GSM1296102U_non-lesional_pre-dose113.7142
GSM1296122V_non-lesional_pre-dose75.2635
GSM1296089W_non-lesional_pre-dose66.334
GSM1296083X_non-lesional_pre-dose79.3738
GSM1296116Y_non-lesional_pre-dose161.2646
GSM1296085Z_non-lesional_pre-dose50.9631