ProfileGDS5420 / 238552_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 25% 39% 43% 39% 22% 36% 38% 24% 29% 41% 41% 41% 33% 41% 39% 43% 36% 36% 26% 33% 37% 37% 45% 41% 35% 42% 45% 39% 43% 35% 26% 45% 36% 43% 43% 40% 39% 41% 26% 49% 46% 44% 39% 40% 38% 40% 29% 39% 35% 38% 27% 40% 17% 34% 36% 29% 44% 37% 43% 41% 38% 23% 45% 41% 40% 42% 33% 28% 35% 33% 29% 42% 32% 42% 17% 44% 42% 25% 29% 39% 33% 43% 40% 24% 44% 50% 40% 33% 39% 43% 47% 40% 37% 34% 38% 42% 31% 48% 32% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose32.5925
GSM1296119B_lesional_pre-dose91.9339
GSM1296076C_lesional_pre-dose103.5443
GSM1296092D_lesional_pre-dose73.0539
GSM1296103E_lesional_pre-dose24.7322
GSM1296078F_lesional_pre-dose67.2336
GSM1296107G_lesional_pre-dose92.238
GSM1296109H_lesional_pre-dose36.1124
GSM1296080I_lesional_pre-dose40.1429
GSM1296090J_lesional_pre-dose89.2841
GSM1296074K_lesional_pre-dose85.0941
GSM1296111L_lesional_pre-dose109.8141
GSM1296099M_lesional_pre-dose59.933
GSM1296086O_lesional_pre-dose91.6241
GSM1296117P_lesional_pre-dose98.539
GSM1296113Q_lesional_pre-dose133.3443
GSM1296096R_lesional_pre-dose66.0636
GSM1296105S_lesional_pre-dose75.9436
GSM1296098T_lesional_pre-dose42.6726
GSM1296101U_lesional_pre-dose56.9933
GSM1296121V_lesional_pre-dose81.0437
GSM1296088W_lesional_pre-dose68.8137
GSM1296082X_lesional_pre-dose113.2745
GSM1296115Y_lesional_pre-dose105.2641
GSM1296084Z_lesional_pre-dose65.4135
GSM1296072B_lesional_day8117.3242
GSM1296069L_lesional_day8149.8845
GSM1296071P_lesional_day8106.9739
GSM1296070Y_lesional_day8131.2343
GSM1296073V_lesional_day868.8235
GSM1296034A_lesional_day1538.5926
GSM1296041G_lesional_day15132.4245
GSM1296035R_lesional_day1561.8736
GSM1296038U_lesional_day15111.543
GSM1296047B_lesional_day15125.8643
GSM1296039E_lesional_day1587.0940
GSM1296042H_lesional_day15102.7439
GSM1296043L_lesional_day15115.5941
GSM1296037M_lesional_day1540.3726
GSM1296046P_lesional_day15178.0749
GSM1296044Q_lesional_day15160.5546
GSM1296045Y_lesional_day15137.4544
GSM1296025C_lesional_day1581.939
GSM1296033D_lesional_day1587.2840
GSM1296027I_lesional_day1568.6438
GSM1296032J_lesional_day1589.7440
GSM1296024K_lesional_day1539.9429
GSM1296031W_lesional_day1591.7439
GSM1296028X_lesional_day1563.1935
GSM1296029Z_lesional_day1578.538
GSM1296026F_lesional_day1538.5727
GSM1296030O_lesional_day1573.9240
GSM1296040S_lesional_day1519.2817
GSM1296036T_lesional_day1566.4734
GSM1296048V_lesional_day1575.9136
GSM1296059A_lesional_day4340.2629
GSM1296066G_lesional_day43135.4844
GSM1296060R_lesional_day4374.5737
GSM1296063U_lesional_day43117.3943
GSM1296064E_lesional_day4393.8141
GSM1296067H_lesional_day4397.2838
GSM1296062M_lesional_day4328.1423
GSM1296068Q_lesional_day43152.1545
GSM1296050C_lesional_day4396.5841
GSM1296057D_lesional_day4388.5440
GSM1296052I_lesional_day4390.2942
GSM1296054J_lesional_day4360.4433
GSM1296049K_lesional_day4340.4628
GSM1296055W_lesional_day4370.5835
GSM1296053X_lesional_day4358.6433
GSM1296058Z_lesional_day4338.4129
GSM1296051F_lesional_day4396.7542
GSM1296056O_lesional_day4346.8432
GSM1296065S_lesional_day43104.0142
GSM1296061T_lesional_day4321.2617
GSM1296095A_non-lesional_pre-dose115.0844
GSM1296120B_non-lesional_pre-dose120.7642
GSM1296077C_non-lesional_pre-dose32.8725
GSM1296093D_non-lesional_pre-dose46.9929
GSM1296104E_non-lesional_pre-dose88.5839
GSM1296079F_non-lesional_pre-dose58.6733
GSM1296108G_non-lesional_pre-dose123.9443
GSM1296110H_non-lesional_pre-dose109.1940
GSM1296081I_non-lesional_pre-dose27.3724
GSM1296091J_non-lesional_pre-dose109.2444
GSM1296075K_non-lesional_pre-dose162.6350
GSM1296112L_non-lesional_pre-dose116.7840
GSM1296100M_non-lesional_pre-dose61.533
GSM1296087O_non-lesional_pre-dose71.0239
GSM1296118P_non-lesional_pre-dose130.7143
GSM1296114Q_non-lesional_pre-dose162.7847
GSM1296097R_non-lesional_pre-dose94.6540
GSM1296106S_non-lesional_pre-dose84.7337
GSM1296102U_non-lesional_pre-dose65.9334
GSM1296122V_non-lesional_pre-dose90.938
GSM1296089W_non-lesional_pre-dose114.5342
GSM1296083X_non-lesional_pre-dose49.4731
GSM1296116Y_non-lesional_pre-dose173.8448
GSM1296085Z_non-lesional_pre-dose54.0632