ProfileGDS5420 / 237248_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 3% 20% 6% 40% 1% 31% 42% 3% 15% 30% 28% 31% 15% 29% 22% 18% 20% 43% 6% 4% 21% 18% 7% 35% 5% 28% 33% 35% 37% 18% 17% 36% 9% 34% 35% 5% 13% 25% 27% 35% 31% 39% 40% 29% 46% 62% 38% 50% 40% 23% 28% 27% 29% 24% 17% 41% 22% 43% 13% 29% 33% 49% 62% 50% 38% 43% 40% 45% 21% 32% 39% 16% 53% 7% 4% 35% 48% 43% 24% 41% 57% 18% 77% 42% 49% 45% 28% 52% 49% 23% 16% 39% 14% 38% 33% 57% 46% 43% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose3.233
GSM1296119B_lesional_pre-dose27.8220
GSM1296076C_lesional_pre-dose6.86
GSM1296092D_lesional_pre-dose75.6240
GSM1296103E_lesional_pre-dose1.011
GSM1296078F_lesional_pre-dose49.7831
GSM1296107G_lesional_pre-dose111.2142
GSM1296109H_lesional_pre-dose3.923
GSM1296080I_lesional_pre-dose14.7115
GSM1296090J_lesional_pre-dose43.9630
GSM1296074K_lesional_pre-dose34.9128
GSM1296111L_lesional_pre-dose59.9331
GSM1296099M_lesional_pre-dose14.6515
GSM1296086O_lesional_pre-dose41.5829
GSM1296117P_lesional_pre-dose34.5722
GSM1296113Q_lesional_pre-dose30.4618
GSM1296096R_lesional_pre-dose20.8620
GSM1296105S_lesional_pre-dose115.2243
GSM1296098T_lesional_pre-dose9.096
GSM1296101U_lesional_pre-dose4.394
GSM1296121V_lesional_pre-dose27.4521
GSM1296088W_lesional_pre-dose18.4518
GSM1296082X_lesional_pre-dose6.387
GSM1296115Y_lesional_pre-dose72.6235
GSM1296084Z_lesional_pre-dose6.015
GSM1296072B_lesional_day846.8528
GSM1296069L_lesional_day873.0133
GSM1296071P_lesional_day879.8135
GSM1296070Y_lesional_day888.9937
GSM1296073V_lesional_day823.818
GSM1296034A_lesional_day1520.4717
GSM1296041G_lesional_day1578.4336
GSM1296035R_lesional_day156.969
GSM1296038U_lesional_day1562.1634
GSM1296047B_lesional_day1576.3135
GSM1296039E_lesional_day155.335
GSM1296042H_lesional_day1516.5313
GSM1296043L_lesional_day1544.0825
GSM1296037M_lesional_day1541.8627
GSM1296046P_lesional_day1579.4935
GSM1296044Q_lesional_day1564.1531
GSM1296045Y_lesional_day15107.5539
GSM1296025C_lesional_day1588.7240
GSM1296033D_lesional_day1543.4229
GSM1296027I_lesional_day15116.7246
GSM1296032J_lesional_day15361.4962
GSM1296024K_lesional_day1573.3438
GSM1296031W_lesional_day15186.7950
GSM1296028X_lesional_day1590.4740
GSM1296029Z_lesional_day1527.4423
GSM1296026F_lesional_day1542.4628
GSM1296030O_lesional_day1530.2727
GSM1296040S_lesional_day1546.7629
GSM1296036T_lesional_day15
GSM1296048V_lesional_day1537.4824
GSM1296059A_lesional_day4316.3117
GSM1296066G_lesional_day43109.8441
GSM1296060R_lesional_day4325.5822
GSM1296063U_lesional_day43117.4143
GSM1296064E_lesional_day4313.213
GSM1296067H_lesional_day4351.4729
GSM1296062M_lesional_day4357.2933
GSM1296068Q_lesional_day43191.5249
GSM1296050C_lesional_day43349.6162
GSM1296057D_lesional_day43168.1450
GSM1296052I_lesional_day4368.3638
GSM1296054J_lesional_day43114.243
GSM1296049K_lesional_day4388.2840
GSM1296055W_lesional_day43135.2645
GSM1296053X_lesional_day4325.4921
GSM1296058Z_lesional_day4347.6932
GSM1296051F_lesional_day4380.9639
GSM1296056O_lesional_day4315.2216
GSM1296065S_lesional_day43209.9653
GSM1296061T_lesional_day438.67
GSM1296095A_non-lesional_pre-dose4.394
GSM1296120B_non-lesional_pre-dose78.4635
GSM1296077C_non-lesional_pre-dose144.3648
GSM1296093D_non-lesional_pre-dose118.7243
GSM1296104E_non-lesional_pre-dose33.124
GSM1296079F_non-lesional_pre-dose96.5941
GSM1296108G_non-lesional_pre-dose269.7757
GSM1296110H_non-lesional_pre-dose25.4318
GSM1296081I_non-lesional_pre-dose879.9177
GSM1296091J_non-lesional_pre-dose99.9142
GSM1296075K_non-lesional_pre-dose152.6249
GSM1296112L_non-lesional_pre-dose156.3845
GSM1296100M_non-lesional_pre-dose41.928
GSM1296087O_non-lesional_pre-dose175.8652
GSM1296118P_non-lesional_pre-dose179.949
GSM1296114Q_non-lesional_pre-dose38.5823
GSM1296097R_non-lesional_pre-dose16.4616
GSM1296106S_non-lesional_pre-dose93.7339
GSM1296102U_non-lesional_pre-dose15.0814
GSM1296122V_non-lesional_pre-dose91.8438
GSM1296089W_non-lesional_pre-dose62.6933
GSM1296083X_non-lesional_pre-dose267.0457
GSM1296116Y_non-lesional_pre-dose157.0646
GSM1296085Z_non-lesional_pre-dose113.1543