ProfileGDS5420 / 236988_x_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 38% 47% 22% 11% 21% 35% 38% 25% 19% 47% 10% 34% 40% 30% 31% 34% 38% 33% 46% 44% 37% 15% 46% 40% 29% 45% 36% 19% 48% 22% 47% 48% 40% 41% 37% 30% 45% 40% 34% 38% 33% 54% 29% 8% 14% 37% 19% 6% 39% 33% 31% 28% 36% 28% 33% 46% 47% 35% 48% 36% 13% 35% 18% 23% 40% 17% 28% 45% 44% 30% 34% 55% 39% 50% 41% 19% 5% 41% 28% 26% 37% 24% 36% 34% 5% 25% 17% 32% 31% 38% 32% 17% 49% 39% 23% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose78.4438
GSM1296119B_lesional_pre-dose150.1647
GSM1296076C_lesional_pre-dose29.5522
GSM1296092D_lesional_pre-dose9.1711
GSM1296103E_lesional_pre-dose24.2821
GSM1296078F_lesional_pre-dose62.2335
GSM1296107G_lesional_pre-dose88.5938
GSM1296109H_lesional_pre-dose40.3125
GSM1296080I_lesional_pre-dose20.6719
GSM1296090J_lesional_pre-dose134.947
GSM1296074K_lesional_pre-dose9.0510
GSM1296111L_lesional_pre-dose75.7934
GSM1296099M_lesional_pre-dose93.3440
GSM1296086O_lesional_pre-dose4430
GSM1296117P_lesional_pre-dose60.3631
GSM1296113Q_lesional_pre-dose82.3734
GSM1296096R_lesional_pre-dose77.8838
GSM1296105S_lesional_pre-dose60.2133
GSM1296098T_lesional_pre-dose137.0446
GSM1296101U_lesional_pre-dose126.0744
GSM1296121V_lesional_pre-dose78.8637
GSM1296088W_lesional_pre-dose15.3215
GSM1296082X_lesional_pre-dose118.1846
GSM1296115Y_lesional_pre-dose99.7840
GSM1296084Z_lesional_pre-dose47.2929
GSM1296072B_lesional_day8135.9145
GSM1296069L_lesional_day886.5936
GSM1296071P_lesional_day829.6519
GSM1296070Y_lesional_day8174.5648
GSM1296073V_lesional_day831.5722
GSM1296034A_lesional_day15155.2347
GSM1296041G_lesional_day15161.6548
GSM1296035R_lesional_day1584.7840
GSM1296038U_lesional_day1598.8641
GSM1296047B_lesional_day1585.3737
GSM1296039E_lesional_day1547.6830
GSM1296042H_lesional_day15139.1345
GSM1296043L_lesional_day15111.0140
GSM1296037M_lesional_day1568.1334
GSM1296046P_lesional_day1599.4938
GSM1296044Q_lesional_day1570.4833
GSM1296045Y_lesional_day15236.2454
GSM1296025C_lesional_day1543.1529
GSM1296033D_lesional_day157.728
GSM1296027I_lesional_day1511.9614
GSM1296032J_lesional_day1574.9137
GSM1296024K_lesional_day1521.4519
GSM1296031W_lesional_day155.916
GSM1296028X_lesional_day1585.6839
GSM1296029Z_lesional_day1555.5233
GSM1296026F_lesional_day1550.2631
GSM1296030O_lesional_day1533.1528
GSM1296040S_lesional_day1570.8936
GSM1296036T_lesional_day1545.6228
GSM1296048V_lesional_day1566.2133
GSM1296059A_lesional_day43129.3946
GSM1296066G_lesional_day43159.547
GSM1296060R_lesional_day4364.6635
GSM1296063U_lesional_day43158.4348
GSM1296064E_lesional_day4366.4936
GSM1296067H_lesional_day4316.0713
GSM1296062M_lesional_day4363.8735
GSM1296068Q_lesional_day4328.2218
GSM1296050C_lesional_day43
GSM1296057D_lesional_day4327.3523
GSM1296052I_lesional_day43
GSM1296054J_lesional_day4395.8840
GSM1296049K_lesional_day4318.5417
GSM1296055W_lesional_day4344.0428
GSM1296053X_lesional_day43129.645
GSM1296058Z_lesional_day43111.0344
GSM1296051F_lesional_day4346.5930
GSM1296056O_lesional_day4356.3234
GSM1296065S_lesional_day43240.9155
GSM1296061T_lesional_day4390.3139
GSM1296095A_non-lesional_pre-dose169.750
GSM1296120B_non-lesional_pre-dose110.7541
GSM1296077C_non-lesional_pre-dose22.1519
GSM1296093D_non-lesional_pre-dose5.535
GSM1296104E_non-lesional_pre-dose101.4741
GSM1296079F_non-lesional_pre-dose
GSM1296108G_non-lesional_pre-dose45.9128
GSM1296110H_non-lesional_pre-dose45.726
GSM1296081I_non-lesional_pre-dose
GSM1296091J_non-lesional_pre-dose72.5537
GSM1296075K_non-lesional_pre-dose31.1224
GSM1296112L_non-lesional_pre-dose90.3736
GSM1296100M_non-lesional_pre-dose65.7634
GSM1296087O_non-lesional_pre-dose4.925
GSM1296118P_non-lesional_pre-dose43.6125
GSM1296114Q_non-lesional_pre-dose25.6817
GSM1296097R_non-lesional_pre-dose54.7532
GSM1296106S_non-lesional_pre-dose57.3631
GSM1296102U_non-lesional_pre-dose85.2238
GSM1296122V_non-lesional_pre-dose63.5832
GSM1296089W_non-lesional_pre-dose20.5617
GSM1296083X_non-lesional_pre-dose167.5149
GSM1296116Y_non-lesional_pre-dose106.5239
GSM1296085Z_non-lesional_pre-dose29.4123