ProfileGDS5420 / 235701_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 75% 69% 63% 58% 74% 61% 71% 75% 63% 58% 65% 69% 66% 57% 71% 73% 69% 72% 81% 72% 72% 64% 61% 71% 61% 75% 71% 73% 69% 74% 73% 73% 71% 68% 73% 70% 72% 73% 69% 76% 74% 68% 63% 60% 53% 58% 66% 65% 62% 58% 60% 53% 72% 79% 70% 69% 73% 72% 67% 68% 72% 71% 76% 66% 71% 58% 66% 63% 69% 66% 65% 61% 67% 67% 77% 72% 72% 68% 62% 70% 61% 74% 77% 44% 62% 66% 71% 70% 59% 75% 76% 65% 75% 71% 71% 69% 60% 73% 60% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose812.1575
GSM1296119B_lesional_pre-dose532.4469
GSM1296076C_lesional_pre-dose351.263
GSM1296092D_lesional_pre-dose265.3958
GSM1296103E_lesional_pre-dose752.8774
GSM1296078F_lesional_pre-dose310.9961
GSM1296107G_lesional_pre-dose590.2371
GSM1296109H_lesional_pre-dose778.4575
GSM1296080I_lesional_pre-dose366.7763
GSM1296090J_lesional_pre-dose27358
GSM1296074K_lesional_pre-dose395.3565
GSM1296111L_lesional_pre-dose550.3869
GSM1296099M_lesional_pre-dose453.0466
GSM1296086O_lesional_pre-dose253.4757
GSM1296117P_lesional_pre-dose620.1471
GSM1296113Q_lesional_pre-dose694.9773
GSM1296096R_lesional_pre-dose549.0369
GSM1296105S_lesional_pre-dose654.2772
GSM1296098T_lesional_pre-dose1116.6581
GSM1296101U_lesional_pre-dose673.3472
GSM1296121V_lesional_pre-dose630.0272
GSM1296088W_lesional_pre-dose396.4464
GSM1296082X_lesional_pre-dose318.2161
GSM1296115Y_lesional_pre-dose608.2171
GSM1296084Z_lesional_pre-dose343.4961
GSM1296072B_lesional_day8793.2575
GSM1296069L_lesional_day8600.1771
GSM1296071P_lesional_day8697.9673
GSM1296070Y_lesional_day8553.1469
GSM1296073V_lesional_day8717.8674
GSM1296034A_lesional_day15723.7773
GSM1296041G_lesional_day15676.573
GSM1296035R_lesional_day15637.8171
GSM1296038U_lesional_day15514.0968
GSM1296047B_lesional_day15674.9773
GSM1296039E_lesional_day15555.5770
GSM1296042H_lesional_day15637.6472
GSM1296043L_lesional_day15671.9873
GSM1296037M_lesional_day15555.3169
GSM1296046P_lesional_day15804.6576
GSM1296044Q_lesional_day15736.5774
GSM1296045Y_lesional_day15507.1468
GSM1296025C_lesional_day15371.8763
GSM1296033D_lesional_day15328.6460
GSM1296027I_lesional_day15195.1553
GSM1296032J_lesional_day15290.1458
GSM1296024K_lesional_day15453.6266
GSM1296031W_lesional_day15449.8865
GSM1296028X_lesional_day15359.1162
GSM1296029Z_lesional_day15283.9658
GSM1296026F_lesional_day15305.6460
GSM1296030O_lesional_day15184.8753
GSM1296040S_lesional_day15652.3372
GSM1296036T_lesional_day15962.6679
GSM1296048V_lesional_day15570.7370
GSM1296059A_lesional_day43543.9869
GSM1296066G_lesional_day43670.0873
GSM1296060R_lesional_day43657.1172
GSM1296063U_lesional_day43461.4967
GSM1296064E_lesional_day43487.8668
GSM1296067H_lesional_day43644.4972
GSM1296062M_lesional_day43627.8371
GSM1296068Q_lesional_day43790.7476
GSM1296050C_lesional_day43447.3966
GSM1296057D_lesional_day43619.7171
GSM1296052I_lesional_day43262.8358
GSM1296054J_lesional_day43478.6466
GSM1296049K_lesional_day43364.7963
GSM1296055W_lesional_day43565.269
GSM1296053X_lesional_day43457.3766
GSM1296058Z_lesional_day43437.5265
GSM1296051F_lesional_day43323.7761
GSM1296056O_lesional_day43463.2267
GSM1296065S_lesional_day43478.6167
GSM1296061T_lesional_day43895.3677
GSM1296095A_non-lesional_pre-dose646.5272
GSM1296120B_non-lesional_pre-dose631.8772
GSM1296077C_non-lesional_pre-dose507.2168
GSM1296093D_non-lesional_pre-dose371.0962
GSM1296104E_non-lesional_pre-dose556.8570
GSM1296079F_non-lesional_pre-dose326.6661
GSM1296108G_non-lesional_pre-dose725.674
GSM1296110H_non-lesional_pre-dose880.0577
GSM1296081I_non-lesional_pre-dose108.2344
GSM1296091J_non-lesional_pre-dose342.4862
GSM1296075K_non-lesional_pre-dose421.4966
GSM1296112L_non-lesional_pre-dose616.571
GSM1296100M_non-lesional_pre-dose590.8370
GSM1296087O_non-lesional_pre-dose268.1459
GSM1296118P_non-lesional_pre-dose773.3875
GSM1296114Q_non-lesional_pre-dose824.7276
GSM1296097R_non-lesional_pre-dose417.4265
GSM1296106S_non-lesional_pre-dose795.9575
GSM1296102U_non-lesional_pre-dose624.7671
GSM1296122V_non-lesional_pre-dose597.7871
GSM1296089W_non-lesional_pre-dose539.3469
GSM1296083X_non-lesional_pre-dose330.4660
GSM1296116Y_non-lesional_pre-dose694.2273
GSM1296085Z_non-lesional_pre-dose327.6160