ProfileGDS5420 / 235469_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 66% 66% 69% 59% 72% 68% 67% 72% 72% 61% 65% 72% 63% 65% 68% 70% 62% 65% 72% 63% 69% 68% 65% 65% 61% 63% 67% 67% 64% 64% 77% 65% 58% 61% 68% 58% 66% 68% 58% 69% 73% 66% 76% 62% 65% 69% 68% 69% 67% 68% 73% 64% 71% 77% 63% 63% 68% 63% 62% 65% 67% 67% 72% 73% 55% 67% 74% 76% 60% 71% 46% 68% 53% 65% 76% 63% 68% 74% 73% 63% 73% 67% 76% 77% 63% 69% 72% 61% 60% 72% 75% 61% 71% 65% 65% 68% 75% 71% 64% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
Graph caption help
SampleTitleValueRank
GSM1296094A_lesional_pre-dose464.2566
GSM1296119B_lesional_pre-dose455.666
GSM1296076C_lesional_pre-dose519.8269
GSM1296092D_lesional_pre-dose281.7259
GSM1296103E_lesional_pre-dose647.5672
GSM1296078F_lesional_pre-dose485.3568
GSM1296107G_lesional_pre-dose471.6367
GSM1296109H_lesional_pre-dose637.7672
GSM1296080I_lesional_pre-dose661.9672
GSM1296090J_lesional_pre-dose312.5361
GSM1296074K_lesional_pre-dose383.1365
GSM1296111L_lesional_pre-dose623.2772
GSM1296099M_lesional_pre-dose392.4663
GSM1296086O_lesional_pre-dose401.965
GSM1296117P_lesional_pre-dose503.2468
GSM1296113Q_lesional_pre-dose589.1570
GSM1296096R_lesional_pre-dose356.5862
GSM1296105S_lesional_pre-dose445.8465
GSM1296098T_lesional_pre-dose655.8472
GSM1296101U_lesional_pre-dose399.9563
GSM1296121V_lesional_pre-dose556.169
GSM1296088W_lesional_pre-dose499.2868
GSM1296082X_lesional_pre-dose410.865
GSM1296115Y_lesional_pre-dose437.3265
GSM1296084Z_lesional_pre-dose335.2661
GSM1296072B_lesional_day8378.0163
GSM1296069L_lesional_day8486.4767
GSM1296071P_lesional_day8493.9367
GSM1296070Y_lesional_day8423.7664
GSM1296073V_lesional_day8400.6164
GSM1296034A_lesional_day15863.7677
GSM1296041G_lesional_day15434.7965
GSM1296035R_lesional_day15291.0358
GSM1296038U_lesional_day15337.3861
GSM1296047B_lesional_day15503.7768
GSM1296039E_lesional_day15274.0658
GSM1296042H_lesional_day15462.8366
GSM1296043L_lesional_day15535.2168
GSM1296037M_lesional_day15294.6358
GSM1296046P_lesional_day15562.8869
GSM1296044Q_lesional_day1567773
GSM1296045Y_lesional_day15455.9166
GSM1296025C_lesional_day15813.6176
GSM1296033D_lesional_day15355.9562
GSM1296027I_lesional_day15415.165
GSM1296032J_lesional_day15550.1969
GSM1296024K_lesional_day15517.4168
GSM1296031W_lesional_day15553.5369
GSM1296028X_lesional_day15473.3267
GSM1296029Z_lesional_day15527.8268
GSM1296026F_lesional_day15681.373
GSM1296030O_lesional_day15388.3664
GSM1296040S_lesional_day15619.8371
GSM1296036T_lesional_day15870.4177
GSM1296048V_lesional_day15376.2963
GSM1296059A_lesional_day43378.6263
GSM1296066G_lesional_day43500.5468
GSM1296060R_lesional_day43380.8663
GSM1296063U_lesional_day43346.4362
GSM1296064E_lesional_day43400.7365
GSM1296067H_lesional_day43508.167
GSM1296062M_lesional_day4349267
GSM1296068Q_lesional_day43660.7172
GSM1296050C_lesional_day43691.1273
GSM1296057D_lesional_day43245.3255
GSM1296052I_lesional_day43467.5167
GSM1296054J_lesional_day43739.5274
GSM1296049K_lesional_day43837.6776
GSM1296055W_lesional_day43322.6360
GSM1296053X_lesional_day43612.2771
GSM1296058Z_lesional_day43128.546
GSM1296051F_lesional_day43489.9768
GSM1296056O_lesional_day43198.8753
GSM1296065S_lesional_day43432.7165
GSM1296061T_lesional_day43837.876
GSM1296095A_non-lesional_pre-dose367.2963
GSM1296120B_non-lesional_pre-dose498.1268
GSM1296077C_non-lesional_pre-dose717.2674
GSM1296093D_non-lesional_pre-dose715.7173
GSM1296104E_non-lesional_pre-dose366.4663
GSM1296079F_non-lesional_pre-dose690.8873
GSM1296108G_non-lesional_pre-dose493.6167
GSM1296110H_non-lesional_pre-dose797.0176
GSM1296081I_non-lesional_pre-dose920.0677
GSM1296091J_non-lesional_pre-dose379.0963
GSM1296075K_non-lesional_pre-dose504.9269
GSM1296112L_non-lesional_pre-dose651.8572
GSM1296100M_non-lesional_pre-dose356.6761
GSM1296087O_non-lesional_pre-dose288.560
GSM1296118P_non-lesional_pre-dose646.272
GSM1296114Q_non-lesional_pre-dose752.1575
GSM1296097R_non-lesional_pre-dose344.4761
GSM1296106S_non-lesional_pre-dose626.9471
GSM1296102U_non-lesional_pre-dose440.1765
GSM1296122V_non-lesional_pre-dose418.9565
GSM1296089W_non-lesional_pre-dose519.9568
GSM1296083X_non-lesional_pre-dose802.4175
GSM1296116Y_non-lesional_pre-dose621.0471
GSM1296085Z_non-lesional_pre-dose416.0464