ProfileGDS5420 / 235430_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 79% 61% 50% 52% 75% 51% 66% 70% 64% 51% 49% 59% 70% 53% 59% 61% 71% 73% 79% 75% 65% 56% 51% 63% 56% 58% 61% 62% 58% 61% 84% 58% 71% 68% 62% 57% 56% 64% 72% 62% 64% 60% 66% 52% 42% 55% 66% 62% 55% 60% 57% 45% 80% 76% 62% 73% 63% 69% 58% 60% 62% 74% 59% 56% 71% 44% 60% 58% 73% 58% 65% 52% 65% 64% 79% 72% 64% 66% 68% 71% 61% 67% 69% 68% 53% 54% 66% 79% 39% 68% 63% 69% 74% 74% 61% 62% 75% 65% 48% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose998.7479
GSM1296119B_lesional_pre-dose335.0261
GSM1296076C_lesional_pre-dose154.2450
GSM1296092D_lesional_pre-dose180.0652
GSM1296103E_lesional_pre-dose774.5975
GSM1296078F_lesional_pre-dose161.6151
GSM1296107G_lesional_pre-dose463.766
GSM1296109H_lesional_pre-dose601.8370
GSM1296080I_lesional_pre-dose392.5764
GSM1296090J_lesional_pre-dose174.2451
GSM1296074K_lesional_pre-dose141.5649
GSM1296111L_lesional_pre-dose299.9959
GSM1296099M_lesional_pre-dose569.3970
GSM1296086O_lesional_pre-dose188.553
GSM1296117P_lesional_pre-dose311.7359
GSM1296113Q_lesional_pre-dose350.8461
GSM1296096R_lesional_pre-dose619.9471
GSM1296105S_lesional_pre-dose707.8773
GSM1296098T_lesional_pre-dose100579
GSM1296101U_lesional_pre-dose787.6475
GSM1296121V_lesional_pre-dose425.4965
GSM1296088W_lesional_pre-dose245.4656
GSM1296082X_lesional_pre-dose167.9751
GSM1296115Y_lesional_pre-dose376.8963
GSM1296084Z_lesional_pre-dose247.9956
GSM1296072B_lesional_day829858
GSM1296069L_lesional_day8361.5261
GSM1296071P_lesional_day8375.6562
GSM1296070Y_lesional_day8291.2558
GSM1296073V_lesional_day8327.6161
GSM1296034A_lesional_day151341.7784
GSM1296041G_lesional_day15284.5758
GSM1296035R_lesional_day15604.2371
GSM1296038U_lesional_day15510.2268
GSM1296047B_lesional_day15373.3562
GSM1296039E_lesional_day15254.857
GSM1296042H_lesional_day15267.6456
GSM1296043L_lesional_day15407.5564
GSM1296037M_lesional_day15647.9472
GSM1296046P_lesional_day15372.9462
GSM1296044Q_lesional_day15421.5864
GSM1296045Y_lesional_day15335.9360
GSM1296025C_lesional_day15456.1366
GSM1296033D_lesional_day15192.352
GSM1296027I_lesional_day1588.0542
GSM1296032J_lesional_day15246.6455
GSM1296024K_lesional_day15443.5666
GSM1296031W_lesional_day15369.2362
GSM1296028X_lesional_day15229.7355
GSM1296029Z_lesional_day15328.1460
GSM1296026F_lesional_day15249.4357
GSM1296030O_lesional_day15106.2145
GSM1296040S_lesional_day151056.6480
GSM1296036T_lesional_day15845.9176
GSM1296048V_lesional_day15354.962
GSM1296059A_lesional_day43695.4573
GSM1296066G_lesional_day43377.8763
GSM1296060R_lesional_day43543.5169
GSM1296063U_lesional_day43279.1558
GSM1296064E_lesional_day43311.8460
GSM1296067H_lesional_day4339162
GSM1296062M_lesional_day43727.1674
GSM1296068Q_lesional_day43331.8759
GSM1296050C_lesional_day43242.1256
GSM1296057D_lesional_day43636.7971
GSM1296052I_lesional_day43107.2244
GSM1296054J_lesional_day43329.9760
GSM1296049K_lesional_day43274.2258
GSM1296055W_lesional_day43690.4673
GSM1296053X_lesional_day43295.1758
GSM1296058Z_lesional_day43417.365
GSM1296051F_lesional_day43185.2652
GSM1296056O_lesional_day43421.2865
GSM1296065S_lesional_day43396.464
GSM1296061T_lesional_day43972.3479
GSM1296095A_non-lesional_pre-dose624.0472
GSM1296120B_non-lesional_pre-dose419.3264
GSM1296077C_non-lesional_pre-dose437.7266
GSM1296093D_non-lesional_pre-dose516.2868
GSM1296104E_non-lesional_pre-dose615.1171
GSM1296079F_non-lesional_pre-dose324.6361
GSM1296108G_non-lesional_pre-dose492.9367
GSM1296110H_non-lesional_pre-dose552.3169
GSM1296081I_non-lesional_pre-dose507.5768
GSM1296091J_non-lesional_pre-dose203.3953
GSM1296075K_non-lesional_pre-dose206.9754
GSM1296112L_non-lesional_pre-dose461.7866
GSM1296100M_non-lesional_pre-dose1010.1479
GSM1296087O_non-lesional_pre-dose70.9839
GSM1296118P_non-lesional_pre-dose509.6368
GSM1296114Q_non-lesional_pre-dose402.8363
GSM1296097R_non-lesional_pre-dose544.3869
GSM1296106S_non-lesional_pre-dose729.3974
GSM1296102U_non-lesional_pre-dose740.5774
GSM1296122V_non-lesional_pre-dose337.6761
GSM1296089W_non-lesional_pre-dose363.3462
GSM1296083X_non-lesional_pre-dose773.3575
GSM1296116Y_non-lesional_pre-dose456.665
GSM1296085Z_non-lesional_pre-dose157.0248