ProfileGDS5420 / 235034_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 59% 57% 60% 59% 66% 59% 60% 60% 57% 54% 58% 56% 57% 59% 56% 56% 61% 60% 62% 54% 57% 57% 59% 58% 55% 59% 55% 53% 61% 59% 50% 56% 58% 63% 55% 59% 61% 61% 48% 52% 54% 61% 49% 53% 47% 51% 48% 55% 51% 47% 55% 53% 59% 58% 53% 59% 55% 55% 60% 60% 47% 53% 48% 51% 53% 44% 48% 43% 49% 47% 59% 56% 57% 64% 61% 55% 54% 47% 56% 56% 45% 51% 54% 50% 46% 49% 52% 48% 48% 44% 47% 52% 51% 48% 45% 59% 50% 51% 53% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose303.6459
GSM1296119B_lesional_pre-dose270.2957
GSM1296076C_lesional_pre-dose284.7760
GSM1296092D_lesional_pre-dose270.5959
GSM1296103E_lesional_pre-dose446.2966
GSM1296078F_lesional_pre-dose270.0859
GSM1296107G_lesional_pre-dose316.560
GSM1296109H_lesional_pre-dose330.6560
GSM1296080I_lesional_pre-dose258.8357
GSM1296090J_lesional_pre-dose199.8854
GSM1296074K_lesional_pre-dose256.0258
GSM1296111L_lesional_pre-dose256.2656
GSM1296099M_lesional_pre-dose269.5357
GSM1296086O_lesional_pre-dose281.1159
GSM1296117P_lesional_pre-dose261.7356
GSM1296113Q_lesional_pre-dose271.9356
GSM1296096R_lesional_pre-dose332.7161
GSM1296105S_lesional_pre-dose320.560
GSM1296098T_lesional_pre-dose370.0262
GSM1296101U_lesional_pre-dose227.4354
GSM1296121V_lesional_pre-dose262.8557
GSM1296088W_lesional_pre-dose250.657
GSM1296082X_lesional_pre-dose270.8359
GSM1296115Y_lesional_pre-dose284.4158
GSM1296084Z_lesional_pre-dose232.0755
GSM1296072B_lesional_day830359
GSM1296069L_lesional_day8260.4855
GSM1296071P_lesional_day8231.5253
GSM1296070Y_lesional_day8348.8961
GSM1296073V_lesional_day8288.0359
GSM1296034A_lesional_day15181.5150
GSM1296041G_lesional_day15258.2356
GSM1296035R_lesional_day15281.5158
GSM1296038U_lesional_day15387.0463
GSM1296047B_lesional_day15246.4755
GSM1296039E_lesional_day15290.5459
GSM1296042H_lesional_day15344.7761
GSM1296043L_lesional_day15350.3761
GSM1296037M_lesional_day15162.2748
GSM1296046P_lesional_day15213.5252
GSM1296044Q_lesional_day15236.9554
GSM1296045Y_lesional_day15351.9361
GSM1296025C_lesional_day15157.2549
GSM1296033D_lesional_day15213.3553
GSM1296027I_lesional_day15126.7147
GSM1296032J_lesional_day15185.2451
GSM1296024K_lesional_day1514748
GSM1296031W_lesional_day15247.2255
GSM1296028X_lesional_day15177.0451
GSM1296029Z_lesional_day15143.3847
GSM1296026F_lesional_day15224.4855
GSM1296030O_lesional_day15183.0953
GSM1296040S_lesional_day15307.6359
GSM1296036T_lesional_day15307.958
GSM1296048V_lesional_day15215.9453
GSM1296059A_lesional_day43299.7359
GSM1296066G_lesional_day43252.1355
GSM1296060R_lesional_day43246.6355
GSM1296063U_lesional_day43324.4160
GSM1296064E_lesional_day43303.8360
GSM1296067H_lesional_day43158.8647
GSM1296062M_lesional_day43219.8153
GSM1296068Q_lesional_day43181.6948
GSM1296050C_lesional_day43184.8551
GSM1296057D_lesional_day43207.4153
GSM1296052I_lesional_day43104.5144
GSM1296054J_lesional_day43160.9448
GSM1296049K_lesional_day43111.7443
GSM1296055W_lesional_day43175.2449
GSM1296053X_lesional_day43139.3447
GSM1296058Z_lesional_day43304.2659
GSM1296051F_lesional_day43235.7456
GSM1296056O_lesional_day43255.6757
GSM1296065S_lesional_day43404.0664
GSM1296061T_lesional_day43350.4661
GSM1296095A_non-lesional_pre-dose230.7755
GSM1296120B_non-lesional_pre-dose229.5154
GSM1296077C_non-lesional_pre-dose132.1647
GSM1296093D_non-lesional_pre-dose260.1856
GSM1296104E_non-lesional_pre-dose249.2756
GSM1296079F_non-lesional_pre-dose117.5245
GSM1296108G_non-lesional_pre-dose190.2151
GSM1296110H_non-lesional_pre-dose248.6654
GSM1296081I_non-lesional_pre-dose156.4750
GSM1296091J_non-lesional_pre-dose128.8946
GSM1296075K_non-lesional_pre-dose146.8949
GSM1296112L_non-lesional_pre-dose224.452
GSM1296100M_non-lesional_pre-dose158.0448
GSM1296087O_non-lesional_pre-dose130.8448
GSM1296118P_non-lesional_pre-dose140.244
GSM1296114Q_non-lesional_pre-dose166.6147
GSM1296097R_non-lesional_pre-dose193.4552
GSM1296106S_non-lesional_pre-dose192.1851
GSM1296102U_non-lesional_pre-dose163.748
GSM1296122V_non-lesional_pre-dose140.1745
GSM1296089W_non-lesional_pre-dose318.4859
GSM1296083X_non-lesional_pre-dose170.9750
GSM1296116Y_non-lesional_pre-dose206.8351
GSM1296085Z_non-lesional_pre-dose210.0853