ProfileGDS5420 / 234387_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 31% 35% 36% 42% 33% 39% 33% 29% 41% 42% 44% 40% 38% 42% 44% 41% 35% 32% 44% 27% 34% 39% 41% 42% 39% 35% 39% 43% 39% 23% 40% 40% 32% 42% 37% 42% 36% 42% 37% 44% 46% 37% 42% 45% 49% 41% 46% 43% 46% 44% 34% 42% 41% 40% 27% 30% 40% 29% 33% 36% 35% 33% 41% 42% 34% 45% 48% 43% 35% 45% 25% 37% 25% 43% 35% 47% 42% 39% 42% 34% 41% 44% 43% 37% 49% 47% 43% 34% 36% 45% 48% 41% 42% 34% 33% 47% 35% 46% 44% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
Graph caption help
SampleTitleValueRank
GSM1296094A_lesional_pre-dose50.1531
GSM1296119B_lesional_pre-dose73.3235
GSM1296076C_lesional_pre-dose67.5636
GSM1296092D_lesional_pre-dose88.7942
GSM1296103E_lesional_pre-dose53.8933
GSM1296078F_lesional_pre-dose79.9339
GSM1296107G_lesional_pre-dose65.633
GSM1296109H_lesional_pre-dose49.9429
GSM1296080I_lesional_pre-dose88.8741
GSM1296090J_lesional_pre-dose95.8542
GSM1296074K_lesional_pre-dose99.8744
GSM1296111L_lesional_pre-dose105.2740
GSM1296099M_lesional_pre-dose78.2138
GSM1296086O_lesional_pre-dose96.1542
GSM1296117P_lesional_pre-dose135.3744
GSM1296113Q_lesional_pre-dose118.8241
GSM1296096R_lesional_pre-dose61.4835
GSM1296105S_lesional_pre-dose56.3832
GSM1296098T_lesional_pre-dose126.6344
GSM1296101U_lesional_pre-dose37.5527
GSM1296121V_lesional_pre-dose67.7534
GSM1296088W_lesional_pre-dose82.1539
GSM1296082X_lesional_pre-dose86.4941
GSM1296115Y_lesional_pre-dose113.4242
GSM1296084Z_lesional_pre-dose87.6139
GSM1296072B_lesional_day872.1335
GSM1296069L_lesional_day8103.1339
GSM1296071P_lesional_day8130.9543
GSM1296070Y_lesional_day8101.4539
GSM1296073V_lesional_day832.223
GSM1296034A_lesional_day15100.4340
GSM1296041G_lesional_day1599.3440
GSM1296035R_lesional_day1546.7932
GSM1296038U_lesional_day15105.5142
GSM1296047B_lesional_day1588.5637
GSM1296039E_lesional_day15101.3242
GSM1296042H_lesional_day1583.9636
GSM1296043L_lesional_day15121.7342
GSM1296037M_lesional_day1581.7437
GSM1296046P_lesional_day15137.8644
GSM1296044Q_lesional_day15152.9546
GSM1296045Y_lesional_day1594.0837
GSM1296025C_lesional_day1599.3642
GSM1296033D_lesional_day15124.5145
GSM1296027I_lesional_day15140.7549
GSM1296032J_lesional_day15100.2241
GSM1296024K_lesional_day15126.7246
GSM1296031W_lesional_day15115.5943
GSM1296028X_lesional_day15127.546
GSM1296029Z_lesional_day15115.7544
GSM1296026F_lesional_day1562.6734
GSM1296030O_lesional_day1586.4942
GSM1296040S_lesional_day15104.6441
GSM1296036T_lesional_day15100.4440
GSM1296048V_lesional_day1545.0127
GSM1296059A_lesional_day4342.5530
GSM1296066G_lesional_day43106.4540
GSM1296060R_lesional_day4341.1929
GSM1296063U_lesional_day4359.0533
GSM1296064E_lesional_day4366.7736
GSM1296067H_lesional_day4378.4635
GSM1296062M_lesional_day4355.7733
GSM1296068Q_lesional_day43122.5841
GSM1296050C_lesional_day43108.7842
GSM1296057D_lesional_day4356.6734
GSM1296052I_lesional_day43112.3745
GSM1296054J_lesional_day43163.8448
GSM1296049K_lesional_day43112.4543
GSM1296055W_lesional_day4370.4635
GSM1296053X_lesional_day43122.7345
GSM1296058Z_lesional_day4328.9825
GSM1296051F_lesional_day4371.3737
GSM1296056O_lesional_day4330.2125
GSM1296065S_lesional_day43114.0843
GSM1296061T_lesional_day437135
GSM1296095A_non-lesional_pre-dose134.4747
GSM1296120B_non-lesional_pre-dose115.1142
GSM1296077C_non-lesional_pre-dose83.0139
GSM1296093D_non-lesional_pre-dose110.6842
GSM1296104E_non-lesional_pre-dose62.7534
GSM1296079F_non-lesional_pre-dose95.7241
GSM1296108G_non-lesional_pre-dose131.6444
GSM1296110H_non-lesional_pre-dose130.1143
GSM1296081I_non-lesional_pre-dose65.2237
GSM1296091J_non-lesional_pre-dose154.2749
GSM1296075K_non-lesional_pre-dose127.9347
GSM1296112L_non-lesional_pre-dose138.3243
GSM1296100M_non-lesional_pre-dose62.434
GSM1296087O_non-lesional_pre-dose59.4936
GSM1296118P_non-lesional_pre-dose147.3445
GSM1296114Q_non-lesional_pre-dose175.4348
GSM1296097R_non-lesional_pre-dose101.341
GSM1296106S_non-lesional_pre-dose115.3842
GSM1296102U_non-lesional_pre-dose64.0134
GSM1296122V_non-lesional_pre-dose67.1333
GSM1296089W_non-lesional_pre-dose150.5747
GSM1296083X_non-lesional_pre-dose65.7735
GSM1296116Y_non-lesional_pre-dose158.7446
GSM1296085Z_non-lesional_pre-dose116.1744