ProfileGDS5420 / 233946_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 56% 59% 69% 62% 61% 70% 61% 54% 57% 60% 63% 64% 52% 61% 63% 60% 54% 61% 53% 59% 55% 62% 54% 62% 62% 60% 63% 59% 63% 61% 54% 62% 54% 62% 60% 57% 63% 64% 58% 64% 64% 65% 61% 63% 64% 61% 60% 60% 54% 59% 65% 64% 57% 59% 60% 59% 66% 53% 67% 63% 58% 54% 62% 66% 56% 62% 55% 60% 60% 57% 53% 67% 54% 62% 55% 63% 58% 61% 53% 55% 67% 63% 63% 60% 61% 66% 65% 47% 67% 63% 64% 52% 57% 54% 54% 67% 54% 66% 63% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
Graph caption help
SampleTitleValueRank
GSM1296094A_lesional_pre-dose261.5956
GSM1296119B_lesional_pre-dose296.5359
GSM1296076C_lesional_pre-dose514.5769
GSM1296092D_lesional_pre-dose338.5162
GSM1296103E_lesional_pre-dose329.7361
GSM1296078F_lesional_pre-dose558.4870
GSM1296107G_lesional_pre-dose333.1461
GSM1296109H_lesional_pre-dose243.1354
GSM1296080I_lesional_pre-dose251.4957
GSM1296090J_lesional_pre-dose302.1860
GSM1296074K_lesional_pre-dose347.8163
GSM1296111L_lesional_pre-dose409.0464
GSM1296099M_lesional_pre-dose193.7452
GSM1296086O_lesional_pre-dose310.7461
GSM1296117P_lesional_pre-dose394.7563
GSM1296113Q_lesional_pre-dose34360
GSM1296096R_lesional_pre-dose221.554
GSM1296105S_lesional_pre-dose352.5761
GSM1296098T_lesional_pre-dose212.3153
GSM1296101U_lesional_pre-dose315.1759
GSM1296121V_lesional_pre-dose238.3455
GSM1296088W_lesional_pre-dose342.6862
GSM1296082X_lesional_pre-dose195.6454
GSM1296115Y_lesional_pre-dose361.6462
GSM1296084Z_lesional_pre-dose363.9362
GSM1296072B_lesional_day8319.6360
GSM1296069L_lesional_day8388.8263
GSM1296071P_lesional_day8313.9259
GSM1296070Y_lesional_day8401.8963
GSM1296073V_lesional_day8336.261
GSM1296034A_lesional_day15237.1954
GSM1296041G_lesional_day15348.0362
GSM1296035R_lesional_day15212.4454
GSM1296038U_lesional_day15363.9562
GSM1296047B_lesional_day15331.9760
GSM1296039E_lesional_day15260.757
GSM1296042H_lesional_day15383.963
GSM1296043L_lesional_day15417.9464
GSM1296037M_lesional_day15282.1558
GSM1296046P_lesional_day15428.1264
GSM1296044Q_lesional_day15415.0364
GSM1296045Y_lesional_day15435.5165
GSM1296025C_lesional_day15332.1561
GSM1296033D_lesional_day15376.6763
GSM1296027I_lesional_day15377.5664
GSM1296032J_lesional_day15352.5761
GSM1296024K_lesional_day15311.1160
GSM1296031W_lesional_day15325.3860
GSM1296028X_lesional_day15220.8454
GSM1296029Z_lesional_day15307.8559
GSM1296026F_lesional_day15405.9965
GSM1296030O_lesional_day15385.8164
GSM1296040S_lesional_day15272.7457
GSM1296036T_lesional_day15313.759
GSM1296048V_lesional_day15322.8260
GSM1296059A_lesional_day43287.3959
GSM1296066G_lesional_day43452.7566
GSM1296060R_lesional_day43207.3953
GSM1296063U_lesional_day43466.5467
GSM1296064E_lesional_day43373.6863
GSM1296067H_lesional_day43314.8258
GSM1296062M_lesional_day43225.754
GSM1296068Q_lesional_day43382.0662
GSM1296050C_lesional_day43433.4866
GSM1296057D_lesional_day43247.2856
GSM1296052I_lesional_day43346.8462
GSM1296054J_lesional_day43242.3155
GSM1296049K_lesional_day43313.4960
GSM1296055W_lesional_day43322.0360
GSM1296053X_lesional_day43267.5757
GSM1296058Z_lesional_day43206.4353
GSM1296051F_lesional_day43455.7767
GSM1296056O_lesional_day43207.5754
GSM1296065S_lesional_day43369.8762
GSM1296061T_lesional_day43234.5655
GSM1296095A_non-lesional_pre-dose363.0863
GSM1296120B_non-lesional_pre-dose292.4758
GSM1296077C_non-lesional_pre-dose326.3961
GSM1296093D_non-lesional_pre-dose215.8153
GSM1296104E_non-lesional_pre-dose242.9655
GSM1296079F_non-lesional_pre-dose457.7967
GSM1296108G_non-lesional_pre-dose389.2263
GSM1296110H_non-lesional_pre-dose405.7263
GSM1296081I_non-lesional_pre-dose296.2460
GSM1296091J_non-lesional_pre-dose318.6261
GSM1296075K_non-lesional_pre-dose429.5666
GSM1296112L_non-lesional_pre-dose457.8265
GSM1296100M_non-lesional_pre-dose155.7847
GSM1296087O_non-lesional_pre-dose469.4267
GSM1296118P_non-lesional_pre-dose402.2163
GSM1296114Q_non-lesional_pre-dose423.664
GSM1296097R_non-lesional_pre-dose202.5452
GSM1296106S_non-lesional_pre-dose282.6957
GSM1296102U_non-lesional_pre-dose234.4954
GSM1296122V_non-lesional_pre-dose237.4754
GSM1296089W_non-lesional_pre-dose487.1567
GSM1296083X_non-lesional_pre-dose228.8654
GSM1296116Y_non-lesional_pre-dose477.8966
GSM1296085Z_non-lesional_pre-dose375.7963