ProfileGDS5420 / 233230_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 17% 42% 39% 42% 26% 41% 45% 41% 19% 42% 43% 57% 26% 38% 49% 45% 29% 21% 8% 25% 41% 29% 44% 52% 30% 35% 48% 42% 42% 42% 6% 52% 21% 26% 33% 14% 44% 42% 23% 48% 44% 44% 24% 30% 31% 30% 22% 25% 27% 30% 15% 23% 24% 24% 37% 19% 52% 27% 35% 34% 31% 17% 39% 31% 23% 27% 22% 24% 19% 12% 7% 33% 24% 34% 16% 33% 36% 17% 22% 15% 19% 41% 41% 3% 42% 42% 42% 8% 33% 41% 46% 24% 25% 21% 29% 29% 18% 49% 25% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose18.1317
GSM1296119B_lesional_pre-dose114.5942
GSM1296076C_lesional_pre-dose83.6539
GSM1296092D_lesional_pre-dose86.5242
GSM1296103E_lesional_pre-dose35.3526
GSM1296078F_lesional_pre-dose92.6741
GSM1296107G_lesional_pre-dose138.645
GSM1296109H_lesional_pre-dose106.5441
GSM1296080I_lesional_pre-dose20.2519
GSM1296090J_lesional_pre-dose96.3842
GSM1296074K_lesional_pre-dose92.5943
GSM1296111L_lesional_pre-dose272.0857
GSM1296099M_lesional_pre-dose36.926
GSM1296086O_lesional_pre-dose71.0338
GSM1296117P_lesional_pre-dose173.3949
GSM1296113Q_lesional_pre-dose148.0245
GSM1296096R_lesional_pre-dose40.3229
GSM1296105S_lesional_pre-dose26.9621
GSM1296098T_lesional_pre-dose11.428
GSM1296101U_lesional_pre-dose32.625
GSM1296121V_lesional_pre-dose106.2941
GSM1296088W_lesional_pre-dose41.5929
GSM1296082X_lesional_pre-dose104.544
GSM1296115Y_lesional_pre-dose206.0352
GSM1296084Z_lesional_pre-dose49.3930
GSM1296072B_lesional_day873.4235
GSM1296069L_lesional_day8176.7448
GSM1296071P_lesional_day8122.2542
GSM1296070Y_lesional_day8125.3842
GSM1296073V_lesional_day8106.742
GSM1296034A_lesional_day156.36
GSM1296041G_lesional_day15201.6952
GSM1296035R_lesional_day1521.2721
GSM1296038U_lesional_day1534.6726
GSM1296047B_lesional_day1567.8633
GSM1296039E_lesional_day1515.8114
GSM1296042H_lesional_day15134.7844
GSM1296043L_lesional_day15124.5342
GSM1296037M_lesional_day1532.5623
GSM1296046P_lesional_day15173.5348
GSM1296044Q_lesional_day15135.0444
GSM1296045Y_lesional_day15138.0144
GSM1296025C_lesional_day1531.6924
GSM1296033D_lesional_day1543.8530
GSM1296027I_lesional_day1541.231
GSM1296032J_lesional_day1545.2130
GSM1296024K_lesional_day1525.0622
GSM1296031W_lesional_day1534.5725
GSM1296028X_lesional_day1536.2627
GSM1296029Z_lesional_day1545.4430
GSM1296026F_lesional_day1517.9215
GSM1296030O_lesional_day1524.1523
GSM1296040S_lesional_day1533.5324
GSM1296036T_lesional_day1535.0524
GSM1296048V_lesional_day1582.4837
GSM1296059A_lesional_day4319.2719
GSM1296066G_lesional_day43205.3152
GSM1296060R_lesional_day4337.4327
GSM1296063U_lesional_day4367.835
GSM1296064E_lesional_day4359.0934
GSM1296067H_lesional_day4361.4431
GSM1296062M_lesional_day4318.1317
GSM1296068Q_lesional_day43108.1539
GSM1296050C_lesional_day4351.7631
GSM1296057D_lesional_day4326.3523
GSM1296052I_lesional_day4332.327
GSM1296054J_lesional_day4327.7722
GSM1296049K_lesional_day4332.1724
GSM1296055W_lesional_day4322.8819
GSM1296053X_lesional_day431212
GSM1296058Z_lesional_day435.867
GSM1296051F_lesional_day4357.133
GSM1296056O_lesional_day4327.7924
GSM1296065S_lesional_day4361.8934
GSM1296061T_lesional_day4318.3716
GSM1296095A_non-lesional_pre-dose55.4933
GSM1296120B_non-lesional_pre-dose84.9336
GSM1296077C_non-lesional_pre-dose18.8417
GSM1296093D_non-lesional_pre-dose27.9622
GSM1296104E_non-lesional_pre-dose18.1515
GSM1296079F_non-lesional_pre-dose24.1919
GSM1296108G_non-lesional_pre-dose104.4241
GSM1296110H_non-lesional_pre-dose120.6341
GSM1296081I_non-lesional_pre-dose2.323
GSM1296091J_non-lesional_pre-dose95.742
GSM1296075K_non-lesional_pre-dose95.3942
GSM1296112L_non-lesional_pre-dose130.4442
GSM1296100M_non-lesional_pre-dose7.998
GSM1296087O_non-lesional_pre-dose50.6833
GSM1296118P_non-lesional_pre-dose119.5441
GSM1296114Q_non-lesional_pre-dose157.6846
GSM1296097R_non-lesional_pre-dose29.7424
GSM1296106S_non-lesional_pre-dose37.7225
GSM1296102U_non-lesional_pre-dose25.821
GSM1296122V_non-lesional_pre-dose53.3829
GSM1296089W_non-lesional_pre-dose47.929
GSM1296083X_non-lesional_pre-dose19.2818
GSM1296116Y_non-lesional_pre-dose186.7449
GSM1296085Z_non-lesional_pre-dose34.4825