ProfileGDS5420 / 232797_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 60% 64% 48% 45% 50% 57% 68% 61% 55% 45% 55% 69% 53% 40% 67% 72% 49% 58% 65% 48% 68% 55% 48% 64% 47% 62% 74% 67% 65% 60% 60% 69% 44% 54% 64% 41% 69% 73% 40% 69% 73% 70% 61% 51% 43% 54% 63% 56% 40% 51% 59% 41% 50% 68% 59% 41% 70% 49% 53% 45% 65% 47% 70% 60% 38% 38% 54% 62% 54% 46% 32% 52% 36% 54% 66% 56% 71% 55% 65% 51% 59% 72% 76% 48% 45% 59% 73% 50% 45% 74% 76% 49% 60% 58% 68% 57% 52% 75% 48% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose319.0260
GSM1296119B_lesional_pre-dose392.9164
GSM1296076C_lesional_pre-dose143.4548
GSM1296092D_lesional_pre-dose107.3545
GSM1296103E_lesional_pre-dose174.3650
GSM1296078F_lesional_pre-dose231.9157
GSM1296107G_lesional_pre-dose508.3768
GSM1296109H_lesional_pre-dose349.0361
GSM1296080I_lesional_pre-dose226.6855
GSM1296090J_lesional_pre-dose117.8645
GSM1296074K_lesional_pre-dose211.1655
GSM1296111L_lesional_pre-dose543.7769
GSM1296099M_lesional_pre-dose210.9653
GSM1296086O_lesional_pre-dose85.6240
GSM1296117P_lesional_pre-dose487.8167
GSM1296113Q_lesional_pre-dose639.5172
GSM1296096R_lesional_pre-dose159.3449
GSM1296105S_lesional_pre-dose289.2958
GSM1296098T_lesional_pre-dose420.5465
GSM1296101U_lesional_pre-dose160.2248
GSM1296121V_lesional_pre-dose520.7368
GSM1296088W_lesional_pre-dose22655
GSM1296082X_lesional_pre-dose136.1448
GSM1296115Y_lesional_pre-dose409.9364
GSM1296084Z_lesional_pre-dose138.0747
GSM1296072B_lesional_day8369.5662
GSM1296069L_lesional_day8719.3574
GSM1296071P_lesional_day8493.8167
GSM1296070Y_lesional_day8440.1865
GSM1296073V_lesional_day8305.7560
GSM1296034A_lesional_day15346.4260
GSM1296041G_lesional_day15543.7469
GSM1296035R_lesional_day15111.3744
GSM1296038U_lesional_day15227.4354
GSM1296047B_lesional_day15401.3664
GSM1296039E_lesional_day1596.2141
GSM1296042H_lesional_day15547.7469
GSM1296043L_lesional_day15688.6673
GSM1296037M_lesional_day1596.7440
GSM1296046P_lesional_day15558.0969
GSM1296044Q_lesional_day15686.7773
GSM1296045Y_lesional_day15568.6270
GSM1296025C_lesional_day15330.261
GSM1296033D_lesional_day15184.8951
GSM1296027I_lesional_day1595.5343
GSM1296032J_lesional_day15217.7554
GSM1296024K_lesional_day15368.363
GSM1296031W_lesional_day15255.6356
GSM1296028X_lesional_day1588.0640
GSM1296029Z_lesional_day15180.0451
GSM1296026F_lesional_day15292.1259
GSM1296030O_lesional_day1580.7941
GSM1296040S_lesional_day15173.1250
GSM1296036T_lesional_day15534.2368
GSM1296048V_lesional_day15309.359
GSM1296059A_lesional_day4393.1141
GSM1296066G_lesional_day43580.5970
GSM1296060R_lesional_day43165.5249
GSM1296063U_lesional_day43212.1553
GSM1296064E_lesional_day43124.6445
GSM1296067H_lesional_day43459.1865
GSM1296062M_lesional_day43146.0547
GSM1296068Q_lesional_day43580.5170
GSM1296050C_lesional_day43314.8460
GSM1296057D_lesional_day4378.3438
GSM1296052I_lesional_day4371.0738
GSM1296054J_lesional_day43227.3954
GSM1296049K_lesional_day43352.1262
GSM1296055W_lesional_day43239.8454
GSM1296053X_lesional_day43133.2146
GSM1296058Z_lesional_day4347.7432
GSM1296051F_lesional_day43185.5952
GSM1296056O_lesional_day4364.8236
GSM1296065S_lesional_day43225.4754
GSM1296061T_lesional_day43485.2266
GSM1296095A_non-lesional_pre-dose242.4756
GSM1296120B_non-lesional_pre-dose592.0771
GSM1296077C_non-lesional_pre-dose230.3455
GSM1296093D_non-lesional_pre-dose452.7765
GSM1296104E_non-lesional_pre-dose186.4751
GSM1296079F_non-lesional_pre-dose286.1159
GSM1296108G_non-lesional_pre-dose658.3572
GSM1296110H_non-lesional_pre-dose797.5376
GSM1296081I_non-lesional_pre-dose141.8348
GSM1296091J_non-lesional_pre-dose114.6845
GSM1296075K_non-lesional_pre-dose272.1959
GSM1296112L_non-lesional_pre-dose684.773
GSM1296100M_non-lesional_pre-dose185.7450
GSM1296087O_non-lesional_pre-dose107.0745
GSM1296118P_non-lesional_pre-dose747.6774
GSM1296114Q_non-lesional_pre-dose817.4776
GSM1296097R_non-lesional_pre-dose165.6849
GSM1296106S_non-lesional_pre-dose332.5260
GSM1296102U_non-lesional_pre-dose297.358
GSM1296122V_non-lesional_pre-dose515.368
GSM1296089W_non-lesional_pre-dose281.3557
GSM1296083X_non-lesional_pre-dose192.0152
GSM1296116Y_non-lesional_pre-dose774.2475
GSM1296085Z_non-lesional_pre-dose156.1548