ProfileGDS5420 / 232586_x_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 74% 64% 62% 63% 68% 56% 62% 62% 74% 63% 61% 60% 63% 60% 62% 73% 59% 73% 78% 71% 64% 67% 56% 58% 71% 69% 64% 73% 64% 66% 90% 60% 60% 66% 75% 64% 62% 69% 75% 71% 74% 71% 81% 70% 68% 77% 78% 80% 73% 71% 67% 64% 69% 83% 66% 66% 63% 66% 64% 61% 67% 72% 70% 71% 72% 66% 86% 76% 71% 77% 68% 59% 61% 69% 77% 71% 69% 74% 86% 68% 70% 69% 69% 81% 69% 66% 74% 76% 65% 75% 70% 68% 73% 82% 71% 79% 83% 67% 76% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
Graph caption help
SampleTitleValueRank
GSM1296094A_lesional_pre-dose746.0974
GSM1296119B_lesional_pre-dose398.4764
GSM1296076C_lesional_pre-dose323.2762
GSM1296092D_lesional_pre-dose366.5763
GSM1296103E_lesional_pre-dose520.8668
GSM1296078F_lesional_pre-dose230.1556
GSM1296107G_lesional_pre-dose359.9662
GSM1296109H_lesional_pre-dose380.0562
GSM1296080I_lesional_pre-dose729.9874
GSM1296090J_lesional_pre-dose366.7663
GSM1296074K_lesional_pre-dose308.8961
GSM1296111L_lesional_pre-dose316.5360
GSM1296099M_lesional_pre-dose385.6663
GSM1296086O_lesional_pre-dose301.1160
GSM1296117P_lesional_pre-dose362.0162
GSM1296113Q_lesional_pre-dose675.5273
GSM1296096R_lesional_pre-dose296.8859
GSM1296105S_lesional_pre-dose702.2573
GSM1296098T_lesional_pre-dose906.7178
GSM1296101U_lesional_pre-dose632.9271
GSM1296121V_lesional_pre-dose409.4664
GSM1296088W_lesional_pre-dose474.2667
GSM1296082X_lesional_pre-dose233.6456
GSM1296115Y_lesional_pre-dose291.3358
GSM1296084Z_lesional_pre-dose600.7471
GSM1296072B_lesional_day8540.7969
GSM1296069L_lesional_day8409.7264
GSM1296071P_lesional_day8695.8473
GSM1296070Y_lesional_day8411.1964
GSM1296073V_lesional_day8440.1466
GSM1296034A_lesional_day152008.9690
GSM1296041G_lesional_day15325.1660
GSM1296035R_lesional_day15328.6860
GSM1296038U_lesional_day15445.9466
GSM1296047B_lesional_day15779.9975
GSM1296039E_lesional_day15399.0664
GSM1296042H_lesional_day15370.6662
GSM1296043L_lesional_day15539.8469
GSM1296037M_lesional_day15780.1375
GSM1296046P_lesional_day15636.4871
GSM1296044Q_lesional_day15740.9474
GSM1296045Y_lesional_day15611.7371
GSM1296025C_lesional_day151149.5681
GSM1296033D_lesional_day15587.4970
GSM1296027I_lesional_day15504.4868
GSM1296032J_lesional_day15909.2377
GSM1296024K_lesional_day15974.5678
GSM1296031W_lesional_day151084.180
GSM1296028X_lesional_day15682.2973
GSM1296029Z_lesional_day15634.6171
GSM1296026F_lesional_day15460.9367
GSM1296030O_lesional_day15399.1664
GSM1296040S_lesional_day15548.5969
GSM1296036T_lesional_day151237.2383
GSM1296048V_lesional_day15456.9266
GSM1296059A_lesional_day43468.8166
GSM1296066G_lesional_day43391.2763
GSM1296060R_lesional_day43444.7466
GSM1296063U_lesional_day43387.4764
GSM1296064E_lesional_day43326.7161
GSM1296067H_lesional_day43503.4967
GSM1296062M_lesional_day43653.4572
GSM1296068Q_lesional_day43571.470
GSM1296050C_lesional_day43618.1371
GSM1296057D_lesional_day43655.5872
GSM1296052I_lesional_day43430.0666
GSM1296054J_lesional_day431578.3786
GSM1296049K_lesional_day43831.7776
GSM1296055W_lesional_day43634.771
GSM1296053X_lesional_day43875.7577
GSM1296058Z_lesional_day43509.8368
GSM1296051F_lesional_day43287.6759
GSM1296056O_lesional_day43317.9961
GSM1296065S_lesional_day43559.9369
GSM1296061T_lesional_day43906.1177
GSM1296095A_non-lesional_pre-dose612.4471
GSM1296120B_non-lesional_pre-dose545.9569
GSM1296077C_non-lesional_pre-dose753.3774
GSM1296093D_non-lesional_pre-dose1567.3786
GSM1296104E_non-lesional_pre-dose507.668
GSM1296079F_non-lesional_pre-dose582.8270
GSM1296108G_non-lesional_pre-dose532.1969
GSM1296110H_non-lesional_pre-dose553.1469
GSM1296081I_non-lesional_pre-dose1142.8681
GSM1296091J_non-lesional_pre-dose523.1469
GSM1296075K_non-lesional_pre-dose442.7966
GSM1296112L_non-lesional_pre-dose725.4374
GSM1296100M_non-lesional_pre-dose808.2376
GSM1296087O_non-lesional_pre-dose398.7265
GSM1296118P_non-lesional_pre-dose775.6375
GSM1296114Q_non-lesional_pre-dose595.5570
GSM1296097R_non-lesional_pre-dose492.8868
GSM1296106S_non-lesional_pre-dose693.1473
GSM1296102U_non-lesional_pre-dose1170.9282
GSM1296122V_non-lesional_pre-dose628.6571
GSM1296089W_non-lesional_pre-dose1006.679
GSM1296083X_non-lesional_pre-dose1286.0883
GSM1296116Y_non-lesional_pre-dose490.5967
GSM1296085Z_non-lesional_pre-dose822.1376