ProfileGDS5420 / 232564_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 31% 32% 35% 27% 33% 43% 34% 28% 43% 44% 33% 33% 38% 36% 14% 17% 44% 41% 34% 37% 27% 45% 40% 33% 56% 38% 31% 29% 38% 21% 41% 33% 40% 39% 36% 26% 33% 37% 38% 36% 27% 41% 52% 52% 47% 49% 47% 50% 57% 57% 46% 49% 42% 33% 30% 40% 27% 48% 38% 29% 42% 34% 27% 52% 37% 49% 44% 47% 54% 63% 46% 46% 32% 37% 32% 36% 39% 53% 58% 39% 54% 43% 35% 46% 44% 49% 45% 51% 53% 33% 26% 52% 46% 36% 34% 61% 54% 43% 52% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose49.0331
GSM1296119B_lesional_pre-dose59.7232
GSM1296076C_lesional_pre-dose62.5435
GSM1296092D_lesional_pre-dose32.7727
GSM1296103E_lesional_pre-dose55.2933
GSM1296078F_lesional_pre-dose101.5843
GSM1296107G_lesional_pre-dose70.2434
GSM1296109H_lesional_pre-dose47.0628
GSM1296080I_lesional_pre-dose97.2543
GSM1296090J_lesional_pre-dose106.2944
GSM1296074K_lesional_pre-dose50.9733
GSM1296111L_lesional_pre-dose68.2433
GSM1296099M_lesional_pre-dose82.8138
GSM1296086O_lesional_pre-dose6436
GSM1296117P_lesional_pre-dose19.3614
GSM1296113Q_lesional_pre-dose28.8517
GSM1296096R_lesional_pre-dose112.3744
GSM1296105S_lesional_pre-dose100.5541
GSM1296098T_lesional_pre-dose67.9134
GSM1296101U_lesional_pre-dose75.3937
GSM1296121V_lesional_pre-dose42.8627
GSM1296088W_lesional_pre-dose11645
GSM1296082X_lesional_pre-dose83.5740
GSM1296115Y_lesional_pre-dose64.7533
GSM1296084Z_lesional_pre-dose251.5756
GSM1296072B_lesional_day888.938
GSM1296069L_lesional_day863.0831
GSM1296071P_lesional_day856.3329
GSM1296070Y_lesional_day897.9938
GSM1296073V_lesional_day82921
GSM1296034A_lesional_day15106.9341
GSM1296041G_lesional_day1563.7533
GSM1296035R_lesional_day1583.6940
GSM1296038U_lesional_day1585.839
GSM1296047B_lesional_day1583.0836
GSM1296039E_lesional_day1536.4726
GSM1296042H_lesional_day1569.0733
GSM1296043L_lesional_day1592.3837
GSM1296037M_lesional_day1588.6738
GSM1296046P_lesional_day1588.236
GSM1296044Q_lesional_day1549.2227
GSM1296045Y_lesional_day15116.1841
GSM1296025C_lesional_day15184.8152
GSM1296033D_lesional_day15192.0452
GSM1296027I_lesional_day15128.3947
GSM1296032J_lesional_day15163.7449
GSM1296024K_lesional_day15140.0547
GSM1296031W_lesional_day15186.2850
GSM1296028X_lesional_day15262.1157
GSM1296029Z_lesional_day15261.2257
GSM1296026F_lesional_day15130.8446
GSM1296030O_lesional_day15143.4949
GSM1296040S_lesional_day15108.4942
GSM1296036T_lesional_day1564.1133
GSM1296048V_lesional_day1554.7130
GSM1296059A_lesional_day4384.2340
GSM1296066G_lesional_day4348.1627
GSM1296060R_lesional_day43147.5348
GSM1296063U_lesional_day4381.1438
GSM1296064E_lesional_day4342.1429
GSM1296067H_lesional_day43123.8342
GSM1296062M_lesional_day4359.8234
GSM1296068Q_lesional_day4352.4827
GSM1296050C_lesional_day43190.1252
GSM1296057D_lesional_day4371.8837
GSM1296052I_lesional_day43150.8649
GSM1296054J_lesional_day43120.8444
GSM1296049K_lesional_day43142.0247
GSM1296055W_lesional_day43238.5754
GSM1296053X_lesional_day43380.363
GSM1296058Z_lesional_day43125.8846
GSM1296051F_lesional_day43123.0446
GSM1296056O_lesional_day4349.0132
GSM1296065S_lesional_day4375.2337
GSM1296061T_lesional_day4355.1232
GSM1296095A_non-lesional_pre-dose67.3636
GSM1296120B_non-lesional_pre-dose96.2839
GSM1296077C_non-lesional_pre-dose194.453
GSM1296093D_non-lesional_pre-dose288.2158
GSM1296104E_non-lesional_pre-dose83.4139
GSM1296079F_non-lesional_pre-dose212.6254
GSM1296108G_non-lesional_pre-dose123.4543
GSM1296110H_non-lesional_pre-dose83.3235
GSM1296081I_non-lesional_pre-dose126.5546
GSM1296091J_non-lesional_pre-dose107.9644
GSM1296075K_non-lesional_pre-dose149.6249
GSM1296112L_non-lesional_pre-dose150.2845
GSM1296100M_non-lesional_pre-dose196.7751
GSM1296087O_non-lesional_pre-dose179.7253
GSM1296118P_non-lesional_pre-dose73.3233
GSM1296114Q_non-lesional_pre-dose45.9726
GSM1296097R_non-lesional_pre-dose202.7652
GSM1296106S_non-lesional_pre-dose145.8246
GSM1296102U_non-lesional_pre-dose76.2836
GSM1296122V_non-lesional_pre-dose73.4734
GSM1296089W_non-lesional_pre-dose346.1361
GSM1296083X_non-lesional_pre-dose225.5654
GSM1296116Y_non-lesional_pre-dose136.4643
GSM1296085Z_non-lesional_pre-dose194.7852