ProfileGDS5420 / 232439_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 59% 55% 44% 49% 54% 46% 56% 46% 66% 49% 47% 45% 54% 38% 50% 49% 52% 63% 63% 52% 48% 51% 47% 41% 57% 58% 48% 58% 50% 38% 79% 43% 50% 54% 60% 47% 51% 48% 64% 57% 55% 50% 73% 56% 69% 71% 76% 58% 55% 61% 62% 55% 62% 66% 47% 50% 50% 54% 55% 46% 63% 62% 56% 61% 60% 62% 70% 71% 59% 68% 57% 53% 47% 54% 67% 57% 58% 66% 73% 59% 67% 57% 55% 70% 59% 56% 48% 70% 63% 65% 55% 62% 61% 67% 58% 61% 67% 57% 58% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose297.7859
GSM1296119B_lesional_pre-dose242.7955
GSM1296076C_lesional_pre-dose112.1944
GSM1296092D_lesional_pre-dose146.6949
GSM1296103E_lesional_pre-dose214.8954
GSM1296078F_lesional_pre-dose125.0246
GSM1296107G_lesional_pre-dose248.5656
GSM1296109H_lesional_pre-dose145.5446
GSM1296080I_lesional_pre-dose448.0566
GSM1296090J_lesional_pre-dose149.6349
GSM1296074K_lesional_pre-dose119.7647
GSM1296111L_lesional_pre-dose136.9245
GSM1296099M_lesional_pre-dose223.0454
GSM1296086O_lesional_pre-dose72.5738
GSM1296117P_lesional_pre-dose187.7850
GSM1296113Q_lesional_pre-dose188.3849
GSM1296096R_lesional_pre-dose197.3252
GSM1296105S_lesional_pre-dose397.8963
GSM1296098T_lesional_pre-dose382.9463
GSM1296101U_lesional_pre-dose207.152
GSM1296121V_lesional_pre-dose162.9648
GSM1296088W_lesional_pre-dose177.8151
GSM1296082X_lesional_pre-dose127.5747
GSM1296115Y_lesional_pre-dose105.9341
GSM1296084Z_lesional_pre-dose271.6157
GSM1296072B_lesional_day8288.4558
GSM1296069L_lesional_day8171.5848
GSM1296071P_lesional_day8309.6958
GSM1296070Y_lesional_day8190.7250
GSM1296073V_lesional_day882.0738
GSM1296034A_lesional_day15996.7579
GSM1296041G_lesional_day15119.8643
GSM1296035R_lesional_day15171.9850
GSM1296038U_lesional_day15215.8954
GSM1296047B_lesional_day15332.160
GSM1296039E_lesional_day15142.2847
GSM1296042H_lesional_day15194.3551
GSM1296043L_lesional_day15172.8848
GSM1296037M_lesional_day15416.7364
GSM1296046P_lesional_day15285.9657
GSM1296044Q_lesional_day15250.5955
GSM1296045Y_lesional_day15196.9750
GSM1296025C_lesional_day15708.7373
GSM1296033D_lesional_day15242.4456
GSM1296027I_lesional_day15546.3769
GSM1296032J_lesional_day15609.3771
GSM1296024K_lesional_day15811.8376
GSM1296031W_lesional_day15293.6958
GSM1296028X_lesional_day15239.4155
GSM1296029Z_lesional_day15341.4361
GSM1296026F_lesional_day15343.9862
GSM1296030O_lesional_day15210.5255
GSM1296040S_lesional_day15374.7862
GSM1296036T_lesional_day15468.966
GSM1296048V_lesional_day15150.0547
GSM1296059A_lesional_day43165.150
GSM1296066G_lesional_day43184.6550
GSM1296060R_lesional_day43224.8554
GSM1296063U_lesional_day43228.4255
GSM1296064E_lesional_day43131.846
GSM1296067H_lesional_day43404.8663
GSM1296062M_lesional_day43378.7862
GSM1296068Q_lesional_day43273.7756
GSM1296050C_lesional_day43332.8561
GSM1296057D_lesional_day43332.0760
GSM1296052I_lesional_day43339.9462
GSM1296054J_lesional_day43603.9770
GSM1296049K_lesional_day43607.0771
GSM1296055W_lesional_day43312.6659
GSM1296053X_lesional_day43512.568
GSM1296058Z_lesional_day43264.6857
GSM1296051F_lesional_day43198.0953
GSM1296056O_lesional_day43128.4247
GSM1296065S_lesional_day43222.6754
GSM1296061T_lesional_day43490.6467
GSM1296095A_non-lesional_pre-dose254.6857
GSM1296120B_non-lesional_pre-dose294.4658
GSM1296077C_non-lesional_pre-dose435.2566
GSM1296093D_non-lesional_pre-dose715.5373
GSM1296104E_non-lesional_pre-dose304.3259
GSM1296079F_non-lesional_pre-dose460.1267
GSM1296108G_non-lesional_pre-dose277.6657
GSM1296110H_non-lesional_pre-dose260.255
GSM1296081I_non-lesional_pre-dose561.8970
GSM1296091J_non-lesional_pre-dose298.2559
GSM1296075K_non-lesional_pre-dose232.5656
GSM1296112L_non-lesional_pre-dose182.0248
GSM1296100M_non-lesional_pre-dose593.1570
GSM1296087O_non-lesional_pre-dose355.6463
GSM1296118P_non-lesional_pre-dose446.5765
GSM1296114Q_non-lesional_pre-dose249.8455
GSM1296097R_non-lesional_pre-dose365.2762
GSM1296106S_non-lesional_pre-dose357.1861
GSM1296102U_non-lesional_pre-dose496.4567
GSM1296122V_non-lesional_pre-dose285.0258
GSM1296089W_non-lesional_pre-dose348.3461
GSM1296083X_non-lesional_pre-dose498.267
GSM1296116Y_non-lesional_pre-dose292.5957
GSM1296085Z_non-lesional_pre-dose287.2358