ProfileGDS5420 / 232423_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 55% 43% 27% 35% 64% 44% 51% 63% 52% 34% 13% 44% 50% 33% 25% 45% 49% 46% 23% 52% 51% 45% 41% 50% 33% 45% 45% 21% 40% 49% 60% 48% 52% 46% 48% 53% 54% 47% 42% 21% 49% 42% 0% 23% 46% 32% 54% 41% 32% 25% 50% 11% 45% 59% 55% 50% 44% 46% 56% 53% 53% 7% 33% 44% 20% 10% 49% 56% 19% 44% 29% 47% 30% 43% 46% 11% 33% 58% 17% 46% 56% 54% 35% 6% 50% 62% 30% 30% 48% 49% 60% 47% 32% 50% 44% 50% 40% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose238.0655
GSM1296119B_lesional_pre-dose118.9243
GSM1296076C_lesional_pre-dose39.4327
GSM1296092D_lesional_pre-dose56.0435
GSM1296103E_lesional_pre-dose412.1364
GSM1296078F_lesional_pre-dose110.9344
GSM1296107G_lesional_pre-dose192.3351
GSM1296109H_lesional_pre-dose404.0763
GSM1296080I_lesional_pre-dose18552
GSM1296090J_lesional_pre-dose55.4834
GSM1296074K_lesional_pre-dose12.3113
GSM1296111L_lesional_pre-dose131.8244
GSM1296099M_lesional_pre-dose173.3950
GSM1296086O_lesional_pre-dose52.6233
GSM1296117P_lesional_pre-dose41.4925
GSM1296113Q_lesional_pre-dose149.6645
GSM1296096R_lesional_pre-dose157.3549
GSM1296105S_lesional_pre-dose144.4446
GSM1296098T_lesional_pre-dose35.3623
GSM1296101U_lesional_pre-dose197.6752
GSM1296121V_lesional_pre-dose191.7351
GSM1296088W_lesional_pre-dose122.3445
GSM1296082X_lesional_pre-dose86.3441
GSM1296115Y_lesional_pre-dose181.0150
GSM1296084Z_lesional_pre-dose58.9833
GSM1296072B_lesional_day8135.0745
GSM1296069L_lesional_day8150.645
GSM1296071P_lesional_day832.6121
GSM1296070Y_lesional_day8109.5640
GSM1296073V_lesional_day8158.5849
GSM1296034A_lesional_day15345.5560
GSM1296041G_lesional_day15156.9648
GSM1296035R_lesional_day15190.4452
GSM1296038U_lesional_day15135.9546
GSM1296047B_lesional_day15162.4748
GSM1296039E_lesional_day15206.2653
GSM1296042H_lesional_day15241.0654
GSM1296043L_lesional_day15163.0347
GSM1296037M_lesional_day15110.2242
GSM1296046P_lesional_day1533.6921
GSM1296044Q_lesional_day15181.1149
GSM1296045Y_lesional_day15126.8642
GSM1296025C_lesional_day150.210
GSM1296033D_lesional_day1528.7323
GSM1296027I_lesional_day15117.2546
GSM1296032J_lesional_day1552.2432
GSM1296024K_lesional_day15
GSM1296031W_lesional_day15236.7754
GSM1296028X_lesional_day1596.1841
GSM1296029Z_lesional_day1551.2932
GSM1296026F_lesional_day15
GSM1296030O_lesional_day1526.4725
GSM1296040S_lesional_day15173.1150
GSM1296036T_lesional_day1513.3211
GSM1296048V_lesional_day15136.3245
GSM1296059A_lesional_day43303.3359
GSM1296066G_lesional_day43243.2955
GSM1296060R_lesional_day43173.8250
GSM1296063U_lesional_day43124.4744
GSM1296064E_lesional_day43131.6746
GSM1296067H_lesional_day43276.8556
GSM1296062M_lesional_day43208.2953
GSM1296068Q_lesional_day43231.7853
GSM1296050C_lesional_day438.197
GSM1296057D_lesional_day4353.1433
GSM1296052I_lesional_day43106.544
GSM1296054J_lesional_day4323.9920
GSM1296049K_lesional_day4310.5410
GSM1296055W_lesional_day43175.1449
GSM1296053X_lesional_day43258.956
GSM1296058Z_lesional_day4319.1319
GSM1296051F_lesional_day43113.1744
GSM1296056O_lesional_day4338.5729
GSM1296065S_lesional_day43150.3547
GSM1296061T_lesional_day4350.6730
GSM1296095A_non-lesional_pre-dose108.643
GSM1296120B_non-lesional_pre-dose149.5246
GSM1296077C_non-lesional_pre-dose11.2811
GSM1296093D_non-lesional_pre-dose59.6733
GSM1296104E_non-lesional_pre-dose274.5158
GSM1296079F_non-lesional_pre-dose19.8417
GSM1296108G_non-lesional_pre-dose148.4546
GSM1296110H_non-lesional_pre-dose280.556
GSM1296081I_non-lesional_pre-dose205.9454
GSM1296091J_non-lesional_pre-dose63.5735
GSM1296075K_non-lesional_pre-dose7.016
GSM1296112L_non-lesional_pre-dose203.2350
GSM1296100M_non-lesional_pre-dose381.6462
GSM1296087O_non-lesional_pre-dose39.9730
GSM1296118P_non-lesional_pre-dose60.9130
GSM1296114Q_non-lesional_pre-dose172.248
GSM1296097R_non-lesional_pre-dose160.449
GSM1296106S_non-lesional_pre-dose340.2660
GSM1296102U_non-lesional_pre-dose158.147
GSM1296122V_non-lesional_pre-dose65.6632
GSM1296089W_non-lesional_pre-dose184.6350
GSM1296083X_non-lesional_pre-dose120.9744
GSM1296116Y_non-lesional_pre-dose197.9550
GSM1296085Z_non-lesional_pre-dose90.2540