ProfileGDS5420 / 232282_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 29% 23% 37% 33% 23% 28% 15% 24% 17% 33% 27% 26% 16% 30% 22% 25% 28% 34% 22% 29% 16% 38% 26% 23% 29% 24% 17% 26% 22% 19% 22% 15% 26% 21% 32% 29% 20% 19% 21% 14% 30% 21% 41% 28% 37% 43% 31% 40% 35% 36% 25% 31% 10% 30% 20% 24% 19% 25% 26% 23% 25% 30% 20% 46% 27% 37% 44% 34% 32% 33% 19% 38% 19% 26% 29% 18% 25% 45% 39% 38% 43% 13% 14% 28% 42% 29% 22% 27% 40% 26% 28% 25% 27% 26% 22% 42% 33% 23% 37% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose43.6729
GSM1296119B_lesional_pre-dose33.9323
GSM1296076C_lesional_pre-dose70.6537
GSM1296092D_lesional_pre-dose50.0433
GSM1296103E_lesional_pre-dose27.2523
GSM1296078F_lesional_pre-dose42.2428
GSM1296107G_lesional_pre-dose20.0115
GSM1296109H_lesional_pre-dose37.524
GSM1296080I_lesional_pre-dose16.9817
GSM1296090J_lesional_pre-dose52.3633
GSM1296074K_lesional_pre-dose33.7327
GSM1296111L_lesional_pre-dose46.3926
GSM1296099M_lesional_pre-dose16.2416
GSM1296086O_lesional_pre-dose43.8430
GSM1296117P_lesional_pre-dose35.5822
GSM1296113Q_lesional_pre-dose48.1425
GSM1296096R_lesional_pre-dose37.4328
GSM1296105S_lesional_pre-dose64.1434
GSM1296098T_lesional_pre-dose33.422
GSM1296101U_lesional_pre-dose44.2429
GSM1296121V_lesional_pre-dose19.9516
GSM1296088W_lesional_pre-dose77.8238
GSM1296082X_lesional_pre-dose32.4326
GSM1296115Y_lesional_pre-dose33.3923
GSM1296084Z_lesional_pre-dose44.8729
GSM1296072B_lesional_day836.424
GSM1296069L_lesional_day824.1217
GSM1296071P_lesional_day844.8726
GSM1296070Y_lesional_day834.9722
GSM1296073V_lesional_day824.119
GSM1296034A_lesional_day1528.7222
GSM1296041G_lesional_day1518.5915
GSM1296035R_lesional_day1530.4826
GSM1296038U_lesional_day1524.8121
GSM1296047B_lesional_day1563.7932
GSM1296039E_lesional_day1545.2929
GSM1296042H_lesional_day1530.8220
GSM1296043L_lesional_day1529.2519
GSM1296037M_lesional_day1527.6121
GSM1296046P_lesional_day1519.5614
GSM1296044Q_lesional_day1560.2130
GSM1296045Y_lesional_day1534.4521
GSM1296025C_lesional_day1594.1741
GSM1296033D_lesional_day1538.1228
GSM1296027I_lesional_day1564.5837
GSM1296032J_lesional_day15110.1243
GSM1296024K_lesional_day1547.831
GSM1296031W_lesional_day1599.4540
GSM1296028X_lesional_day156235
GSM1296029Z_lesional_day1568.0736
GSM1296026F_lesional_day1533.9925
GSM1296030O_lesional_day1539.3931
GSM1296040S_lesional_day1510.9310
GSM1296036T_lesional_day1550.6530
GSM1296048V_lesional_day1527.3820
GSM1296059A_lesional_day4327.8424
GSM1296066G_lesional_day4326.819
GSM1296060R_lesional_day4331.5525
GSM1296063U_lesional_day4338.1826
GSM1296064E_lesional_day4327.9723
GSM1296067H_lesional_day4339.7825
GSM1296062M_lesional_day4345.9730
GSM1296068Q_lesional_day4333.2720
GSM1296050C_lesional_day43132.8246
GSM1296057D_lesional_day4336.7227
GSM1296052I_lesional_day4367.0137
GSM1296054J_lesional_day43126.9444
GSM1296049K_lesional_day4360.0234
GSM1296055W_lesional_day4356.7232
GSM1296053X_lesional_day4358.3733
GSM1296058Z_lesional_day4318.8819
GSM1296051F_lesional_day4375.7138
GSM1296056O_lesional_day4319.0619
GSM1296065S_lesional_day4337.3126
GSM1296061T_lesional_day4345.1629
GSM1296095A_non-lesional_pre-dose18.8418
GSM1296120B_non-lesional_pre-dose40.1525
GSM1296077C_non-lesional_pre-dose120.6945
GSM1296093D_non-lesional_pre-dose90.2139
GSM1296104E_non-lesional_pre-dose77.938
GSM1296079F_non-lesional_pre-dose105.3943
GSM1296108G_non-lesional_pre-dose15.3613
GSM1296110H_non-lesional_pre-dose19.1614
GSM1296081I_non-lesional_pre-dose35.628
GSM1296091J_non-lesional_pre-dose100.5742
GSM1296075K_non-lesional_pre-dose44.2429
GSM1296112L_non-lesional_pre-dose38.7622
GSM1296100M_non-lesional_pre-dose39.0327
GSM1296087O_non-lesional_pre-dose75.6140
GSM1296118P_non-lesional_pre-dose46.9126
GSM1296114Q_non-lesional_pre-dose50.6428
GSM1296097R_non-lesional_pre-dose31.6325
GSM1296106S_non-lesional_pre-dose41.8127
GSM1296102U_non-lesional_pre-dose37.8726
GSM1296122V_non-lesional_pre-dose33.5322
GSM1296089W_non-lesional_pre-dose113.7942
GSM1296083X_non-lesional_pre-dose57.4733
GSM1296116Y_non-lesional_pre-dose41.323
GSM1296085Z_non-lesional_pre-dose76.9537