ProfileGDS5420 / 231987_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 55% 65% 52% 38% 52% 53% 71% 66% 60% 45% 43% 69% 56% 54% 62% 69% 56% 84% 44% 55% 68% 56% 45% 64% 64% 65% 77% 84% 75% 55% 65% 55% 48% 54% 73% 44% 68% 80% 65% 76% 68% 71% 69% 53% 62% 58% 69% 68% 72% 66% 67% 48% 71% 53% 60% 46% 69% 53% 51% 45% 84% 65% 79% 74% 67% 60% 55% 61% 73% 66% 58% 61% 51% 69% 55% 51% 72% 61% 64% 56% 74% 75% 72% 71% 55% 51% 86% 80% 55% 80% 68% 60% 72% 63% 85% 71% 79% 80% 67% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose232.7855
GSM1296119B_lesional_pre-dose423.8465
GSM1296076C_lesional_pre-dose181.652
GSM1296092D_lesional_pre-dose66.5238
GSM1296103E_lesional_pre-dose198.3752
GSM1296078F_lesional_pre-dose186.1753
GSM1296107G_lesional_pre-dose602.9271
GSM1296109H_lesional_pre-dose466.2966
GSM1296080I_lesional_pre-dose300.0760
GSM1296090J_lesional_pre-dose113.9545
GSM1296074K_lesional_pre-dose91.2243
GSM1296111L_lesional_pre-dose530.8169
GSM1296099M_lesional_pre-dose255.7356
GSM1296086O_lesional_pre-dose204.2954
GSM1296117P_lesional_pre-dose363.6762
GSM1296113Q_lesional_pre-dose546.5569
GSM1296096R_lesional_pre-dose241.4956
GSM1296105S_lesional_pre-dose1389.1384
GSM1296098T_lesional_pre-dose122.0544
GSM1296101U_lesional_pre-dose236.7955
GSM1296121V_lesional_pre-dose501.3368
GSM1296088W_lesional_pre-dose246.5556
GSM1296082X_lesional_pre-dose115.5845
GSM1296115Y_lesional_pre-dose398.1164
GSM1296084Z_lesional_pre-dose389.1364
GSM1296072B_lesional_day8427.1565
GSM1296069L_lesional_day8877.0677
GSM1296071P_lesional_day81309.0484
GSM1296070Y_lesional_day8749.375
GSM1296073V_lesional_day8227.7355
GSM1296034A_lesional_day15452.6565
GSM1296041G_lesional_day15242.8955
GSM1296035R_lesional_day15151.448
GSM1296038U_lesional_day15214.4354
GSM1296047B_lesional_day15694.4573
GSM1296039E_lesional_day15116.944
GSM1296042H_lesional_day15521.6568
GSM1296043L_lesional_day151054.2980
GSM1296037M_lesional_day15436.6465
GSM1296046P_lesional_day15797.8976
GSM1296044Q_lesional_day15517.4968
GSM1296045Y_lesional_day15629.0271
GSM1296025C_lesional_day15549.6769
GSM1296033D_lesional_day15210.8853
GSM1296027I_lesional_day15345.5562
GSM1296032J_lesional_day15285.7458
GSM1296024K_lesional_day15540.6669
GSM1296031W_lesional_day15532.2368
GSM1296028X_lesional_day15672.9172
GSM1296029Z_lesional_day15460.4166
GSM1296026F_lesional_day15461.0567
GSM1296030O_lesional_day15128.1948
GSM1296040S_lesional_day15624.8371
GSM1296036T_lesional_day15215.8253
GSM1296048V_lesional_day15321.7560
GSM1296059A_lesional_day43127.6846
GSM1296066G_lesional_day43533.6769
GSM1296060R_lesional_day43210.1953
GSM1296063U_lesional_day43186.2451
GSM1296064E_lesional_day43119.9745
GSM1296067H_lesional_day431305.484
GSM1296062M_lesional_day43449.9565
GSM1296068Q_lesional_day43950.5279
GSM1296050C_lesional_day43715.8574
GSM1296057D_lesional_day43499.5867
GSM1296052I_lesional_day43306.8660
GSM1296054J_lesional_day43244.4155
GSM1296049K_lesional_day43341.3261
GSM1296055W_lesional_day43699.6673
GSM1296053X_lesional_day43462.2866
GSM1296058Z_lesional_day43276.2558
GSM1296051F_lesional_day43318.8661
GSM1296056O_lesional_day43171.9151
GSM1296065S_lesional_day43543.4369
GSM1296061T_lesional_day43245.7155
GSM1296095A_non-lesional_pre-dose184.4151
GSM1296120B_non-lesional_pre-dose656.4472
GSM1296077C_non-lesional_pre-dose328.3561
GSM1296093D_non-lesional_pre-dose420.0264
GSM1296104E_non-lesional_pre-dose258.1756
GSM1296079F_non-lesional_pre-dose722.1274
GSM1296108G_non-lesional_pre-dose766.8775
GSM1296110H_non-lesional_pre-dose659.0472
GSM1296081I_non-lesional_pre-dose595.171
GSM1296091J_non-lesional_pre-dose222.5955
GSM1296075K_non-lesional_pre-dose172.2751
GSM1296112L_non-lesional_pre-dose1453.1486
GSM1296100M_non-lesional_pre-dose1062.3980
GSM1296087O_non-lesional_pre-dose207.8155
GSM1296118P_non-lesional_pre-dose1050.5280
GSM1296114Q_non-lesional_pre-dose515.7968
GSM1296097R_non-lesional_pre-dose314.8260
GSM1296106S_non-lesional_pre-dose666.4472
GSM1296102U_non-lesional_pre-dose396.3963
GSM1296122V_non-lesional_pre-dose1430.4885
GSM1296089W_non-lesional_pre-dose634.8971
GSM1296083X_non-lesional_pre-dose982.0479
GSM1296116Y_non-lesional_pre-dose1024.3780
GSM1296085Z_non-lesional_pre-dose477.7467