ProfileGDS5420 / 231821_x_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 97% 92% 89% 90% 96% 92% 85% 92% 95% 85% 95% 88% 89% 89% 87% 91% 86% 89% 96% 90% 89% 90% 84% 88% 92% 93% 87% 85% 89% 89% 98% 86% 85% 84% 96% 93% 91% 89% 94% 88% 90% 90% 96% 96% 92% 93% 98% 89% 91% 95% 97% 94% 87% 96% 89% 92% 85% 86% 84% 92% 94% 96% 91% 94% 93% 90% 94% 98% 79% 94% 89% 94% 87% 79% 96% 92% 95% 95% 96% 92% 97% 85% 91% 94% 88% 95% 90% 96% 94% 91% 91% 85% 89% 92% 91% 90% 93% 90% 96% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose4297.7497
GSM1296119B_lesional_pre-dose2526.9492
GSM1296076C_lesional_pre-dose2197.2189
GSM1296092D_lesional_pre-dose2356.6590
GSM1296103E_lesional_pre-dose3988.6596
GSM1296078F_lesional_pre-dose2823.2892
GSM1296107G_lesional_pre-dose1454.3885
GSM1296109H_lesional_pre-dose2491.2592
GSM1296080I_lesional_pre-dose3586.5595
GSM1296090J_lesional_pre-dose1578.0185
GSM1296074K_lesional_pre-dose4051.7695
GSM1296111L_lesional_pre-dose1761.0788
GSM1296099M_lesional_pre-dose2013.4889
GSM1296086O_lesional_pre-dose2015.5189
GSM1296117P_lesional_pre-dose1621.8487
GSM1296113Q_lesional_pre-dose2154.6791
GSM1296096R_lesional_pre-dose1573.5486
GSM1296105S_lesional_pre-dose1971.0489
GSM1296098T_lesional_pre-dose3941.5696
GSM1296101U_lesional_pre-dose2188.2890
GSM1296121V_lesional_pre-dose2032.3889
GSM1296088W_lesional_pre-dose2182.8190
GSM1296082X_lesional_pre-dose1471.8784
GSM1296115Y_lesional_pre-dose1822.8588
GSM1296084Z_lesional_pre-dose2647.5292
GSM1296072B_lesional_day82786.0493
GSM1296069L_lesional_day81594.6387
GSM1296071P_lesional_day81437.1485
GSM1296070Y_lesional_day81875.5389
GSM1296073V_lesional_day82086.789
GSM1296034A_lesional_day155400.5598
GSM1296041G_lesional_day151583.7786
GSM1296035R_lesional_day151541.2885
GSM1296038U_lesional_day151361.0984
GSM1296047B_lesional_day153710.4796
GSM1296039E_lesional_day153177.0793
GSM1296042H_lesional_day152205.6291
GSM1296043L_lesional_day151814.3989
GSM1296037M_lesional_day153356.2894
GSM1296046P_lesional_day151763.5988
GSM1296044Q_lesional_day151999.4290
GSM1296045Y_lesional_day151926.990
GSM1296025C_lesional_day153750.8796
GSM1296033D_lesional_day153451.996
GSM1296027I_lesional_day152587.4792
GSM1296032J_lesional_day152799.7593
GSM1296024K_lesional_day155582.5498
GSM1296031W_lesional_day151977.5689
GSM1296028X_lesional_day152313.891
GSM1296029Z_lesional_day153436.4295
GSM1296026F_lesional_day154404.5897
GSM1296030O_lesional_day153229.2394
GSM1296040S_lesional_day151667.4887
GSM1296036T_lesional_day153726.3896
GSM1296048V_lesional_day152015.8389
GSM1296059A_lesional_day432606.0392
GSM1296066G_lesional_day431485.5985
GSM1296060R_lesional_day431597.6186
GSM1296063U_lesional_day431401.2684
GSM1296064E_lesional_day432740.3292
GSM1296067H_lesional_day432765.0394
GSM1296062M_lesional_day433726.9496
GSM1296068Q_lesional_day432200.3591
GSM1296050C_lesional_day433134.5894
GSM1296057D_lesional_day432716.9893
GSM1296052I_lesional_day432230.1490
GSM1296054J_lesional_day432899.6494
GSM1296049K_lesional_day435307.2998
GSM1296055W_lesional_day431019.4479
GSM1296053X_lesional_day432844.7694
GSM1296058Z_lesional_day431937.5489
GSM1296051F_lesional_day433374.5494
GSM1296056O_lesional_day431825.9887
GSM1296065S_lesional_day431027.2379
GSM1296061T_lesional_day433988.3796
GSM1296095A_non-lesional_pre-dose2659.9992
GSM1296120B_non-lesional_pre-dose3238.2695
GSM1296077C_non-lesional_pre-dose3333.6895
GSM1296093D_non-lesional_pre-dose3494.0296
GSM1296104E_non-lesional_pre-dose2895.492
GSM1296079F_non-lesional_pre-dose4245.4497
GSM1296108G_non-lesional_pre-dose1416.7285
GSM1296110H_non-lesional_pre-dose2181.7991
GSM1296081I_non-lesional_pre-dose3188.194
GSM1296091J_non-lesional_pre-dose1845.9488
GSM1296075K_non-lesional_pre-dose3510.0995
GSM1296112L_non-lesional_pre-dose1888.2790
GSM1296100M_non-lesional_pre-dose3903.1396
GSM1296087O_non-lesional_pre-dose3409.5494
GSM1296118P_non-lesional_pre-dose2140.1991
GSM1296114Q_non-lesional_pre-dose2313.2291
GSM1296097R_non-lesional_pre-dose1503.8285
GSM1296106S_non-lesional_pre-dose1912.2189
GSM1296102U_non-lesional_pre-dose2404.1192
GSM1296122V_non-lesional_pre-dose2198.7291
GSM1296089W_non-lesional_pre-dose1988.1590
GSM1296083X_non-lesional_pre-dose2817.3693
GSM1296116Y_non-lesional_pre-dose1910.2290
GSM1296085Z_non-lesional_pre-dose3846.1596