ProfileGDS5420 / 231535_x_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 23% 52% 54% 63% 37% 36% 46% 25% 27% 69% 46% 38% 49% 61% 36% 33% 49% 53% 21% 45% 42% 42% 43% 52% 67% 61% 51% 49% 56% 39% 24% 29% 44% 56% 68% 51% 35% 51% 80% 56% 47% 63% 58% 73% 66% 81% 56% 65% 70% 67% 16% 63% 33% 26% 42% 40% 42% 55% 47% 51% 37% 58% 58% 70% 72% 62% 71% 56% 57% 61% 66% 59% 49% 59% 33% 39% 69% 68% 64% 70% 53% 57% 42% 62% 84% 67% 63% 83% 79% 79% 52% 59% 57% 56% 52% 65% 47% 66% 80% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose28.0923
GSM1296119B_lesional_pre-dose205.6852
GSM1296076C_lesional_pre-dose206.5354
GSM1296092D_lesional_pre-dose358.6863
GSM1296103E_lesional_pre-dose71.8237
GSM1296078F_lesional_pre-dose68.6136
GSM1296107G_lesional_pre-dose146.7446
GSM1296109H_lesional_pre-dose38.8825
GSM1296080I_lesional_pre-dose34.4327
GSM1296090J_lesional_pre-dose522.5469
GSM1296074K_lesional_pre-dose112.6946
GSM1296111L_lesional_pre-dose95.238
GSM1296099M_lesional_pre-dose162.2149
GSM1296086O_lesional_pre-dose319.5261
GSM1296117P_lesional_pre-dose83.5936
GSM1296113Q_lesional_pre-dose75.1233
GSM1296096R_lesional_pre-dose156.6749
GSM1296105S_lesional_pre-dose224.4753
GSM1296098T_lesional_pre-dose32.6921
GSM1296101U_lesional_pre-dose127.7945
GSM1296121V_lesional_pre-dose113.2342
GSM1296088W_lesional_pre-dose100.4642
GSM1296082X_lesional_pre-dose100.2843
GSM1296115Y_lesional_pre-dose198.1452
GSM1296084Z_lesional_pre-dose490.2167
GSM1296072B_lesional_day8348.4661
GSM1296069L_lesional_day8204.8151
GSM1296071P_lesional_day8188.8149
GSM1296070Y_lesional_day8271.6256
GSM1296073V_lesional_day891.0539
GSM1296034A_lesional_day1533.3624
GSM1296041G_lesional_day1551.529
GSM1296035R_lesional_day15112.944
GSM1296038U_lesional_day15245.8356
GSM1296047B_lesional_day15504.3368
GSM1296039E_lesional_day15179.1851
GSM1296042H_lesional_day1577.5635
GSM1296043L_lesional_day15205.4251
GSM1296037M_lesional_day151068.6880
GSM1296046P_lesional_day15267.6356
GSM1296044Q_lesional_day15168.0647
GSM1296045Y_lesional_day15384.7363
GSM1296025C_lesional_day15268.5158
GSM1296033D_lesional_day15685.2873
GSM1296027I_lesional_day15439.6766
GSM1296032J_lesional_day151130.6281
GSM1296024K_lesional_day15238.8556
GSM1296031W_lesional_day15439.1965
GSM1296028X_lesional_day15583.1170
GSM1296029Z_lesional_day15489.6867
GSM1296026F_lesional_day1518.9616
GSM1296030O_lesional_day15357.4363
GSM1296040S_lesional_day1559.1133
GSM1296036T_lesional_day1539.2626
GSM1296048V_lesional_day15109.0942
GSM1296059A_lesional_day4383.6540
GSM1296066G_lesional_day43121.5942
GSM1296060R_lesional_day43240.5555
GSM1296063U_lesional_day43145.0747
GSM1296064E_lesional_day43172.5651
GSM1296067H_lesional_day4389.0437
GSM1296062M_lesional_day43286.3958
GSM1296068Q_lesional_day43307.5558
GSM1296050C_lesional_day43552.6970
GSM1296057D_lesional_day43674.7672
GSM1296052I_lesional_day43339.8262
GSM1296054J_lesional_day43627.8471
GSM1296049K_lesional_day43238.6956
GSM1296055W_lesional_day43281.657
GSM1296053X_lesional_day43348.0561
GSM1296058Z_lesional_day43448.0166
GSM1296051F_lesional_day43280.5159
GSM1296056O_lesional_day43149.3349
GSM1296065S_lesional_day43303.7859
GSM1296061T_lesional_day4362.3433
GSM1296095A_non-lesional_pre-dose82.939
GSM1296120B_non-lesional_pre-dose534.7469
GSM1296077C_non-lesional_pre-dose499.7668
GSM1296093D_non-lesional_pre-dose410.2464
GSM1296104E_non-lesional_pre-dose574.0670
GSM1296079F_non-lesional_pre-dose195.3653
GSM1296108G_non-lesional_pre-dose274.6157
GSM1296110H_non-lesional_pre-dose124.2242
GSM1296081I_non-lesional_pre-dose354.2662
GSM1296091J_non-lesional_pre-dose1401.6684
GSM1296075K_non-lesional_pre-dose466.6467
GSM1296112L_non-lesional_pre-dose391.6463
GSM1296100M_non-lesional_pre-dose1255.2483
GSM1296087O_non-lesional_pre-dose1046.5479
GSM1296118P_non-lesional_pre-dose956.4779
GSM1296114Q_non-lesional_pre-dose211.3252
GSM1296097R_non-lesional_pre-dose301.7959
GSM1296106S_non-lesional_pre-dose286.6157
GSM1296102U_non-lesional_pre-dose263.956
GSM1296122V_non-lesional_pre-dose208.8252
GSM1296089W_non-lesional_pre-dose438.2965
GSM1296083X_non-lesional_pre-dose140.7347
GSM1296116Y_non-lesional_pre-dose466.766
GSM1296085Z_non-lesional_pre-dose1051.4480