ProfileGDS5420 / 230578_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 43% 48% 42% 43% 40% 35% 45% 32% 45% 43% 35% 35% 41% 47% 34% 48% 44% 57% 50% 44% 39% 46% 33% 38% 50% 56% 39% 51% 42% 42% 63% 33% 45% 40% 55% 39% 48% 41% 48% 46% 56% 49% 69% 51% 62% 61% 65% 55% 58% 52% 52% 59% 48% 51% 42% 47% 38% 50% 40% 40% 55% 52% 59% 58% 62% 63% 66% 66% 49% 58% 60% 47% 42% 53% 47% 51% 59% 70% 67% 49% 63% 52% 55% 65% 58% 56% 53% 58% 66% 62% 56% 54% 58% 62% 62% 52% 63% 54% 64% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose108.8543
GSM1296119B_lesional_pre-dose157.7248
GSM1296076C_lesional_pre-dose100.1342
GSM1296092D_lesional_pre-dose97.3343
GSM1296103E_lesional_pre-dose88.5840
GSM1296078F_lesional_pre-dose61.9835
GSM1296107G_lesional_pre-dose139.6845
GSM1296109H_lesional_pre-dose63.1132
GSM1296080I_lesional_pre-dose113.645
GSM1296090J_lesional_pre-dose98.7143
GSM1296074K_lesional_pre-dose57.2635
GSM1296111L_lesional_pre-dose78.135
GSM1296099M_lesional_pre-dose96.6241
GSM1296086O_lesional_pre-dose127.4147
GSM1296117P_lesional_pre-dose71.3134
GSM1296113Q_lesional_pre-dose173.2748
GSM1296096R_lesional_pre-dose111.8844
GSM1296105S_lesional_pre-dose280.9457
GSM1296098T_lesional_pre-dose173.8750
GSM1296101U_lesional_pre-dose125.8944
GSM1296121V_lesional_pre-dose91.0839
GSM1296088W_lesional_pre-dose123.9746
GSM1296082X_lesional_pre-dose49.633
GSM1296115Y_lesional_pre-dose86.9738
GSM1296084Z_lesional_pre-dose175.2350
GSM1296072B_lesional_day8264.0856
GSM1296069L_lesional_day8107.139
GSM1296071P_lesional_day8212.9351
GSM1296070Y_lesional_day8120.8642
GSM1296073V_lesional_day8105.2442
GSM1296034A_lesional_day15398.0463
GSM1296041G_lesional_day1565.1133
GSM1296035R_lesional_day15121.5345
GSM1296038U_lesional_day1589.540
GSM1296047B_lesional_day15254.8155
GSM1296039E_lesional_day1585.0839
GSM1296042H_lesional_day15165.2648
GSM1296043L_lesional_day15114.7641
GSM1296037M_lesional_day15165.1248
GSM1296046P_lesional_day15157.4646
GSM1296044Q_lesional_day15277.2656
GSM1296045Y_lesional_day15182.2349
GSM1296025C_lesional_day15540.9569
GSM1296033D_lesional_day15180.251
GSM1296027I_lesional_day15338.6262
GSM1296032J_lesional_day15342.6461
GSM1296024K_lesional_day15418.665
GSM1296031W_lesional_day15244.955
GSM1296028X_lesional_day15278.3458
GSM1296029Z_lesional_day15191.4952
GSM1296026F_lesional_day15188.0452
GSM1296030O_lesional_day15287.459
GSM1296040S_lesional_day15154.3348
GSM1296036T_lesional_day15199.1651
GSM1296048V_lesional_day15114.9442
GSM1296059A_lesional_day43139.9247
GSM1296066G_lesional_day4394.838
GSM1296060R_lesional_day43175.1250
GSM1296063U_lesional_day4397.4940
GSM1296064E_lesional_day4388.3840
GSM1296067H_lesional_day43253.4455
GSM1296062M_lesional_day43203.852
GSM1296068Q_lesional_day43318.4359
GSM1296050C_lesional_day43283.2758
GSM1296057D_lesional_day43354.662
GSM1296052I_lesional_day43357.8763
GSM1296054J_lesional_day43461.9866
GSM1296049K_lesional_day43453.9266
GSM1296055W_lesional_day43178.3549
GSM1296053X_lesional_day43282.6958
GSM1296058Z_lesional_day43314.9260
GSM1296051F_lesional_day43130.8747
GSM1296056O_lesional_day4395.4242
GSM1296065S_lesional_day43207.3253
GSM1296061T_lesional_day43151.1147
GSM1296095A_non-lesional_pre-dose175.3751
GSM1296120B_non-lesional_pre-dose311.2659
GSM1296077C_non-lesional_pre-dose557.8370
GSM1296093D_non-lesional_pre-dose501.0167
GSM1296104E_non-lesional_pre-dose164.949
GSM1296079F_non-lesional_pre-dose361.8963
GSM1296108G_non-lesional_pre-dose204.6752
GSM1296110H_non-lesional_pre-dose259.7555
GSM1296081I_non-lesional_pre-dose410.3965
GSM1296091J_non-lesional_pre-dose276.3258
GSM1296075K_non-lesional_pre-dose228.0656
GSM1296112L_non-lesional_pre-dose233.0953
GSM1296100M_non-lesional_pre-dose289.5358
GSM1296087O_non-lesional_pre-dose441.3466
GSM1296118P_non-lesional_pre-dose375.3762
GSM1296114Q_non-lesional_pre-dose264.4856
GSM1296097R_non-lesional_pre-dose227.9454
GSM1296106S_non-lesional_pre-dose299.1658
GSM1296102U_non-lesional_pre-dose382.9762
GSM1296122V_non-lesional_pre-dose368.8962
GSM1296089W_non-lesional_pre-dose201.0352
GSM1296083X_non-lesional_pre-dose389.3563
GSM1296116Y_non-lesional_pre-dose245.6754
GSM1296085Z_non-lesional_pre-dose402.3564