ProfileGDS5420 / 230340_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 50% 66% 41% 48% 65% 31% 66% 67% 47% 51% 59% 70% 48% 44% 72% 72% 59% 43% 53% 56% 64% 45% 55% 73% 47% 53% 66% 63% 70% 66% 49% 72% 54% 55% 52% 56% 62% 66% 39% 70% 64% 68% 34% 36% 30% 37% 36% 43% 15% 43% 40% 39% 58% 53% 63% 56% 70% 51% 53% 67% 52% 45% 62% 27% 44% 31% 37% 28% 50% 22% 41% 28% 53% 46% 53% 56% 58% 41% 37% 50% 39% 62% 62% 38% 37% 30% 68% 39% 23% 67% 67% 46% 44% 43% 57% 40% 42% 69% 26% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose169.7950
GSM1296119B_lesional_pre-dose439.7766
GSM1296076C_lesional_pre-dose92.3341
GSM1296092D_lesional_pre-dose135.148
GSM1296103E_lesional_pre-dose420.4765
GSM1296078F_lesional_pre-dose50.4431
GSM1296107G_lesional_pre-dose459.4366
GSM1296109H_lesional_pre-dose505.2267
GSM1296080I_lesional_pre-dose126.947
GSM1296090J_lesional_pre-dose167.2751
GSM1296074K_lesional_pre-dose261.559
GSM1296111L_lesional_pre-dose579.8770
GSM1296099M_lesional_pre-dose153.5848
GSM1296086O_lesional_pre-dose110.3844
GSM1296117P_lesional_pre-dose656.4172
GSM1296113Q_lesional_pre-dose646.872
GSM1296096R_lesional_pre-dose299.9259
GSM1296105S_lesional_pre-dose114.5943
GSM1296098T_lesional_pre-dose216.4153
GSM1296101U_lesional_pre-dose251.2856
GSM1296121V_lesional_pre-dose411.5464
GSM1296088W_lesional_pre-dose117.3845
GSM1296082X_lesional_pre-dose215.155
GSM1296115Y_lesional_pre-dose682.4173
GSM1296084Z_lesional_pre-dose137.4647
GSM1296072B_lesional_day8213.5153
GSM1296069L_lesional_day8476.4266
GSM1296071P_lesional_day8408.0863
GSM1296070Y_lesional_day8580.1270
GSM1296073V_lesional_day8433.4166
GSM1296034A_lesional_day15173.5249
GSM1296041G_lesional_day15645.9772
GSM1296035R_lesional_day15222.4154
GSM1296038U_lesional_day15227.7255
GSM1296047B_lesional_day15204.7952
GSM1296039E_lesional_day15237.256
GSM1296042H_lesional_day15375.1462
GSM1296043L_lesional_day15470.4766
GSM1296037M_lesional_day1590.3839
GSM1296046P_lesional_day15573.4370
GSM1296044Q_lesional_day15423.3664
GSM1296045Y_lesional_day15515.2168
GSM1296025C_lesional_day1562.9734
GSM1296033D_lesional_day1568.9636
GSM1296027I_lesional_day1538.2830
GSM1296032J_lesional_day1575.9537
GSM1296024K_lesional_day1563.6236
GSM1296031W_lesional_day15118.2843
GSM1296028X_lesional_day1515.6815
GSM1296029Z_lesional_day15109.4943
GSM1296026F_lesional_day1586.1840
GSM1296030O_lesional_day1570.0339
GSM1296040S_lesional_day15280.8658
GSM1296036T_lesional_day15219.5153
GSM1296048V_lesional_day15377.7963
GSM1296059A_lesional_day43239.7456
GSM1296066G_lesional_day43577.6970
GSM1296060R_lesional_day43179.8151
GSM1296063U_lesional_day43205.353
GSM1296064E_lesional_day43466.1467
GSM1296067H_lesional_day43214.1452
GSM1296062M_lesional_day43125.9645
GSM1296068Q_lesional_day43385.9662
GSM1296050C_lesional_day4342.0127
GSM1296057D_lesional_day43113.9244
GSM1296052I_lesional_day4342.7531
GSM1296054J_lesional_day4376.4137
GSM1296049K_lesional_day4342.0528
GSM1296055W_lesional_day43182.650
GSM1296053X_lesional_day4327.1422
GSM1296058Z_lesional_day4390.2341
GSM1296051F_lesional_day4340.9228
GSM1296056O_lesional_day43197.2953
GSM1296065S_lesional_day43142.4846
GSM1296061T_lesional_day43211.3553
GSM1296095A_non-lesional_pre-dose251.1456
GSM1296120B_non-lesional_pre-dose293.3558
GSM1296077C_non-lesional_pre-dose92.341
GSM1296093D_non-lesional_pre-dose82.1537
GSM1296104E_non-lesional_pre-dose177.6450
GSM1296079F_non-lesional_pre-dose81.1539
GSM1296108G_non-lesional_pre-dose363.662
GSM1296110H_non-lesional_pre-dose391.5562
GSM1296081I_non-lesional_pre-dose71.1238
GSM1296091J_non-lesional_pre-dose71.5437
GSM1296075K_non-lesional_pre-dose46.930
GSM1296112L_non-lesional_pre-dose528.2468
GSM1296100M_non-lesional_pre-dose91.4239
GSM1296087O_non-lesional_pre-dose25.6823
GSM1296118P_non-lesional_pre-dose505.1267
GSM1296114Q_non-lesional_pre-dose484.1167
GSM1296097R_non-lesional_pre-dose134.8846
GSM1296106S_non-lesional_pre-dose126.7744
GSM1296102U_non-lesional_pre-dose118.5943
GSM1296122V_non-lesional_pre-dose273.1257
GSM1296089W_non-lesional_pre-dose102.5640
GSM1296083X_non-lesional_pre-dose104.9542
GSM1296116Y_non-lesional_pre-dose557.9869
GSM1296085Z_non-lesional_pre-dose36.0326