ProfileGDS5420 / 229703_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 49% 52% 47% 44% 53% 47% 60% 60% 45% 47% 46% 60% 50% 43% 59% 59% 50% 48% 56% 47% 58% 48% 53% 60% 39% 51% 57% 51% 52% 54% 44% 55% 45% 53% 49% 51% 55% 58% 41% 54% 56% 50% 49% 36% 36% 38% 45% 47% 36% 40% 50% 34% 52% 54% 54% 47% 59% 46% 46% 53% 50% 44% 50% 40% 42% 33% 35% 46% 40% 45% 34% 46% 39% 45% 50% 50% 52% 47% 41% 46% 41% 53% 56% 43% 39% 38% 52% 42% 33% 55% 54% 47% 47% 42% 46% 44% 50% 56% 46% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose162.949
GSM1296119B_lesional_pre-dose205.952
GSM1296076C_lesional_pre-dose129.3747
GSM1296092D_lesional_pre-dose103.944
GSM1296103E_lesional_pre-dose200.9653
GSM1296078F_lesional_pre-dose128.8247
GSM1296107G_lesional_pre-dose322.2860
GSM1296109H_lesional_pre-dose324.7560
GSM1296080I_lesional_pre-dose110.1745
GSM1296090J_lesional_pre-dose133.7647
GSM1296074K_lesional_pre-dose114.446
GSM1296111L_lesional_pre-dose328.1960
GSM1296099M_lesional_pre-dose172.0250
GSM1296086O_lesional_pre-dose102.7643
GSM1296117P_lesional_pre-dose303.0259
GSM1296113Q_lesional_pre-dose318.1459
GSM1296096R_lesional_pre-dose169.0250
GSM1296105S_lesional_pre-dose158.248
GSM1296098T_lesional_pre-dose250.8556
GSM1296101U_lesional_pre-dose150.6947
GSM1296121V_lesional_pre-dose288.8658
GSM1296088W_lesional_pre-dose144.4448
GSM1296082X_lesional_pre-dose191.3353
GSM1296115Y_lesional_pre-dose317.8460
GSM1296084Z_lesional_pre-dose89.0139
GSM1296072B_lesional_day8193.4551
GSM1296069L_lesional_day8292.757
GSM1296071P_lesional_day8207.7951
GSM1296070Y_lesional_day8215.8252
GSM1296073V_lesional_day8213.3254
GSM1296034A_lesional_day15131.4344
GSM1296041G_lesional_day15244.355
GSM1296035R_lesional_day15121.4545
GSM1296038U_lesional_day15210.8453
GSM1296047B_lesional_day15177.4949
GSM1296039E_lesional_day15181.9251
GSM1296042H_lesional_day15248.4455
GSM1296043L_lesional_day15302.9658
GSM1296037M_lesional_day15107.1141
GSM1296046P_lesional_day15238.354
GSM1296044Q_lesional_day15271.6956
GSM1296045Y_lesional_day15198.6750
GSM1296025C_lesional_day15156.3149
GSM1296033D_lesional_day1567.8836
GSM1296027I_lesional_day1559.5536
GSM1296032J_lesional_day1580.3638
GSM1296024K_lesional_day15116.7845
GSM1296031W_lesional_day15148.7247
GSM1296028X_lesional_day1567.3536
GSM1296029Z_lesional_day1592.2640
GSM1296026F_lesional_day15162.5450
GSM1296030O_lesional_day1550.0234
GSM1296040S_lesional_day15193.6852
GSM1296036T_lesional_day15234.4154
GSM1296048V_lesional_day15226.5954
GSM1296059A_lesional_day43137.4547
GSM1296066G_lesional_day43299.8359
GSM1296060R_lesional_day43129.8446
GSM1296063U_lesional_day43133.846
GSM1296064E_lesional_day43196.8853
GSM1296067H_lesional_day43193.6550
GSM1296062M_lesional_day43122.1444
GSM1296068Q_lesional_day43201.8450
GSM1296050C_lesional_day4391.2440
GSM1296057D_lesional_day43102.0542
GSM1296052I_lesional_day4349.9233
GSM1296054J_lesional_day4369.3635
GSM1296049K_lesional_day43128.4146
GSM1296055W_lesional_day43100.1640
GSM1296053X_lesional_day43127.2245
GSM1296058Z_lesional_day4354.6534
GSM1296051F_lesional_day43123.8946
GSM1296056O_lesional_day4376.4139
GSM1296065S_lesional_day43126.7945
GSM1296061T_lesional_day43179.7950
GSM1296095A_non-lesional_pre-dose169.4150
GSM1296120B_non-lesional_pre-dose213.952
GSM1296077C_non-lesional_pre-dose136.6547
GSM1296093D_non-lesional_pre-dose103.6141
GSM1296104E_non-lesional_pre-dose133.8546
GSM1296079F_non-lesional_pre-dose96.7141
GSM1296108G_non-lesional_pre-dose221.353
GSM1296110H_non-lesional_pre-dose282.6656
GSM1296081I_non-lesional_pre-dose99.6743
GSM1296091J_non-lesional_pre-dose82.4639
GSM1296075K_non-lesional_pre-dose75.2938
GSM1296112L_non-lesional_pre-dose226.7152
GSM1296100M_non-lesional_pre-dose110.3542
GSM1296087O_non-lesional_pre-dose49.5233
GSM1296118P_non-lesional_pre-dose256.0255
GSM1296114Q_non-lesional_pre-dose241.1354
GSM1296097R_non-lesional_pre-dose144.5147
GSM1296106S_non-lesional_pre-dose153.0247
GSM1296102U_non-lesional_pre-dose111.6942
GSM1296122V_non-lesional_pre-dose148.7846
GSM1296089W_non-lesional_pre-dose128.4244
GSM1296083X_non-lesional_pre-dose170.1150
GSM1296116Y_non-lesional_pre-dose273.256
GSM1296085Z_non-lesional_pre-dose129.8346