ProfileGDS5420 / 229403_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 5% 26% 12% 13% 35% 14% 31% 36% 8% 23% 23% 35% 33% 36% 41% 23% 13% 26% 22% 34% 4% 22% 40% 23% 19% 46% 31% 34% 25% 1% 30% 27% 34% 22% 27% 29% 42% 27% 33% 37% 34% 24% 4% 7% 32% 12% 1% 6% 13% 18% 27% 20% 25% 15% 36% 32% 31% 31% 23% 24% 33% 29% 11% 5% 9% 1% 26% 8% 14% 24% 13% 24% 11% 8% 24% 32% 17% 30% 14% 26% 32% 6% 27% 36% 12% 11% 38% 38% 28% 27% 16% 26% 22% 38% 24% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose5.395
GSM1296119B_lesional_pre-dose41.4126
GSM1296076C_lesional_pre-dose14.5512
GSM1296092D_lesional_pre-dose11.8313
GSM1296103E_lesional_pre-dose61.5535
GSM1296078F_lesional_pre-dose15.9114
GSM1296107G_lesional_pre-dose57.3631
GSM1296109H_lesional_pre-dose79.9436
GSM1296080I_lesional_pre-dose7.238
GSM1296090J_lesional_pre-dose27.6423
GSM1296074K_lesional_pre-dose26.4223
GSM1296111L_lesional_pre-dose79.9935
GSM1296099M_lesional_pre-dose57.5633
GSM1296086O_lesional_pre-dose
GSM1296117P_lesional_pre-dose82.4636
GSM1296113Q_lesional_pre-dose118.7741
GSM1296096R_lesional_pre-dose26.3923
GSM1296105S_lesional_pre-dose13.3113
GSM1296098T_lesional_pre-dose42.7326
GSM1296101U_lesional_pre-dose27.0122
GSM1296121V_lesional_pre-dose66.4434
GSM1296088W_lesional_pre-dose3.64
GSM1296082X_lesional_pre-dose23.8222
GSM1296115Y_lesional_pre-dose97.2940
GSM1296084Z_lesional_pre-dose31.7223
GSM1296072B_lesional_day824.5119
GSM1296069L_lesional_day8154.1746
GSM1296071P_lesional_day866.1931
GSM1296070Y_lesional_day873.7134
GSM1296073V_lesional_day836.7625
GSM1296034A_lesional_day150.871
GSM1296041G_lesional_day1552.7830
GSM1296035R_lesional_day1533.2627
GSM1296038U_lesional_day1562.8434
GSM1296047B_lesional_day1533.4222
GSM1296039E_lesional_day1538.5127
GSM1296042H_lesional_day1555.4629
GSM1296043L_lesional_day15121.5942
GSM1296037M_lesional_day1542.7327
GSM1296046P_lesional_day1572.1533
GSM1296044Q_lesional_day1592.1437
GSM1296045Y_lesional_day1578.6334
GSM1296025C_lesional_day1531.6124
GSM1296033D_lesional_day153.454
GSM1296027I_lesional_day155.867
GSM1296032J_lesional_day1552.5232
GSM1296024K_lesional_day1512.5612
GSM1296031W_lesional_day150.91
GSM1296028X_lesional_day15
GSM1296029Z_lesional_day155.656
GSM1296026F_lesional_day1515.5313
GSM1296030O_lesional_day1515.7418
GSM1296040S_lesional_day1539.2827
GSM1296036T_lesional_day1526.0720
GSM1296048V_lesional_day1538.1525
GSM1296059A_lesional_day4314.6215
GSM1296066G_lesional_day4381.5236
GSM1296060R_lesional_day4351.3232
GSM1296063U_lesional_day4350.8831
GSM1296064E_lesional_day4350.7731
GSM1296067H_lesional_day4334.8723
GSM1296062M_lesional_day4330.2424
GSM1296068Q_lesional_day4378.4633
GSM1296050C_lesional_day4346.3429
GSM1296057D_lesional_day4310.1511
GSM1296052I_lesional_day434.225
GSM1296054J_lesional_day439.569
GSM1296049K_lesional_day430.911
GSM1296055W_lesional_day4338.5526
GSM1296053X_lesional_day437.588
GSM1296058Z_lesional_day4312.0514
GSM1296051F_lesional_day4330.8224
GSM1296056O_lesional_day4311.9913
GSM1296065S_lesional_day4330.3824
GSM1296061T_lesional_day4312.5211
GSM1296095A_non-lesional_pre-dose8.258
GSM1296120B_non-lesional_pre-dose37.5224
GSM1296077C_non-lesional_pre-dose51.3132
GSM1296093D_non-lesional_pre-dose19.1117
GSM1296104E_non-lesional_pre-dose48.5230
GSM1296079F_non-lesional_pre-dose15.6414
GSM1296108G_non-lesional_pre-dose41.7226
GSM1296110H_non-lesional_pre-dose66.2332
GSM1296081I_non-lesional_pre-dose
GSM1296091J_non-lesional_pre-dose5.886
GSM1296075K_non-lesional_pre-dose38.5227
GSM1296112L_non-lesional_pre-dose90.6136
GSM1296100M_non-lesional_pre-dose11.7612
GSM1296087O_non-lesional_pre-dose9.8311
GSM1296118P_non-lesional_pre-dose100.1838
GSM1296114Q_non-lesional_pre-dose99.1338
GSM1296097R_non-lesional_pre-dose38.6228
GSM1296106S_non-lesional_pre-dose42.5127
GSM1296102U_non-lesional_pre-dose17.1316
GSM1296122V_non-lesional_pre-dose45.126
GSM1296089W_non-lesional_pre-dose30.2122
GSM1296083X_non-lesional_pre-dose
GSM1296116Y_non-lesional_pre-dose99.5938
GSM1296085Z_non-lesional_pre-dose32.8624