ProfileGDS5420 / 229396_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 92% 74% 89% 95% 92% 88% 89% 89% 82% 93% 94% 89% 88% 90% 91% 92% 94% 79% 91% 89% 87% 79% 94% 92% 84% 71% 81% 74% 90% 94% 78% 93% 95% 87% 59% 95% 76% 81% 67% 86% 81% 87% 70% 82% 70% 60% 69% 67% 71% 74% 78% 87% 90% 89% 93% 93% 91% 90% 94% 95% 67% 82% 77% 56% 78% 73% 68% 70% 64% 74% 91% 80% 95% 87% 90% 93% 66% 68% 76% 82% 64% 79% 76% 67% 91% 79% 87% 69% 86% 65% 83% 89% 80% 81% 59% 67% 69% 81% 74% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose2418.0792
GSM1296119B_lesional_pre-dose739.2774
GSM1296076C_lesional_pre-dose2217.6589
GSM1296092D_lesional_pre-dose3514.5595
GSM1296103E_lesional_pre-dose2659.6692
GSM1296078F_lesional_pre-dose1911.6788
GSM1296107G_lesional_pre-dose1977.6689
GSM1296109H_lesional_pre-dose1868.8189
GSM1296080I_lesional_pre-dose1272.8582
GSM1296090J_lesional_pre-dose3010.8193
GSM1296074K_lesional_pre-dose3591.9694
GSM1296111L_lesional_pre-dose1951.9989
GSM1296099M_lesional_pre-dose1779.9888
GSM1296086O_lesional_pre-dose2260.7690
GSM1296117P_lesional_pre-dose2232.2591
GSM1296113Q_lesional_pre-dose2445.8592
GSM1296096R_lesional_pre-dose3198.7794
GSM1296105S_lesional_pre-dose979.2779
GSM1296098T_lesional_pre-dose2199.9891
GSM1296101U_lesional_pre-dose2023.2389
GSM1296121V_lesional_pre-dose1673.8787
GSM1296088W_lesional_pre-dose989.0279
GSM1296082X_lesional_pre-dose3345.0494
GSM1296115Y_lesional_pre-dose2571.4992
GSM1296084Z_lesional_pre-dose1378.2384
GSM1296072B_lesional_day8606.8371
GSM1296069L_lesional_day81078.9881
GSM1296071P_lesional_day8735.0574
GSM1296070Y_lesional_day81959.4790
GSM1296073V_lesional_day83323.0794
GSM1296034A_lesional_day15916.2478
GSM1296041G_lesional_day152934.9593
GSM1296035R_lesional_day153574.6295
GSM1296038U_lesional_day151720.9687
GSM1296047B_lesional_day15304.7959
GSM1296039E_lesional_day154153.5695
GSM1296042H_lesional_day15823.7476
GSM1296043L_lesional_day151097.5981
GSM1296037M_lesional_day15485.0867
GSM1296046P_lesional_day151533.3786
GSM1296044Q_lesional_day151089.7981
GSM1296045Y_lesional_day151603.2987
GSM1296025C_lesional_day15557.1670
GSM1296033D_lesional_day151200.3682
GSM1296027I_lesional_day15556.470
GSM1296032J_lesional_day15334.860
GSM1296024K_lesional_day15539.4269
GSM1296031W_lesional_day15498.9367
GSM1296028X_lesional_day15630.6771
GSM1296029Z_lesional_day15761.9774
GSM1296026F_lesional_day15921.0978
GSM1296030O_lesional_day151732.7887
GSM1296040S_lesional_day152155.5590
GSM1296036T_lesional_day151919.1289
GSM1296048V_lesional_day152764.9393
GSM1296059A_lesional_day432845.6993
GSM1296066G_lesional_day432327.5891
GSM1296060R_lesional_day432195.4790
GSM1296063U_lesional_day433300.894
GSM1296064E_lesional_day434076.4995
GSM1296067H_lesional_day43504.0967
GSM1296062M_lesional_day431235.1882
GSM1296068Q_lesional_day43864.4477
GSM1296050C_lesional_day43240.0456
GSM1296057D_lesional_day43941.4478
GSM1296052I_lesional_day43714.5873
GSM1296054J_lesional_day43535.9768
GSM1296049K_lesional_day43571.9870
GSM1296055W_lesional_day43418.2164
GSM1296053X_lesional_day43729.8874
GSM1296058Z_lesional_day432308.1791
GSM1296051F_lesional_day431087.5780
GSM1296056O_lesional_day433676.0495
GSM1296065S_lesional_day431721.1787
GSM1296061T_lesional_day432007.3290
GSM1296095A_non-lesional_pre-dose2947.3393
GSM1296120B_non-lesional_pre-dose447.1566
GSM1296077C_non-lesional_pre-dose488.5468
GSM1296093D_non-lesional_pre-dose854.1976
GSM1296104E_non-lesional_pre-dose1235.4682
GSM1296079F_non-lesional_pre-dose398.1464
GSM1296108G_non-lesional_pre-dose1002.2579
GSM1296110H_non-lesional_pre-dose816.8476
GSM1296081I_non-lesional_pre-dose482.7567
GSM1296091J_non-lesional_pre-dose2304.5591
GSM1296075K_non-lesional_pre-dose978.0879
GSM1296112L_non-lesional_pre-dose1552.8887
GSM1296100M_non-lesional_pre-dose549.669
GSM1296087O_non-lesional_pre-dose1687.8686
GSM1296118P_non-lesional_pre-dose449.5365
GSM1296114Q_non-lesional_pre-dose1247.3783
GSM1296097R_non-lesional_pre-dose1960.2389
GSM1296106S_non-lesional_pre-dose1049.8780
GSM1296102U_non-lesional_pre-dose1084.3581
GSM1296122V_non-lesional_pre-dose304.8259
GSM1296089W_non-lesional_pre-dose483.5167
GSM1296083X_non-lesional_pre-dose552.5969
GSM1296116Y_non-lesional_pre-dose1078.8281
GSM1296085Z_non-lesional_pre-dose753.8274