ProfileGDS5420 / 229346_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 51% 51% 44% 42% 67% 9% 54% 75% 51% 49% 54% 50% 50% 42% 61% 58% 42% 53% 52% 42% 53% 44% 43% 55% 43% 51% 56% 57% 44% 54% 41% 51% 40% 37% 48% 45% 46% 48% 43% 48% 46% 48% 44% 37% 10% 33% 40% 47% 28% 35% 25% 34% 54% 52% 49% 55% 41% 30% 38% 51% 51% 49% 54% 27% 42% 32% 34% 42% 53% 33% 47% 42% 48% 38% 51% 37% 45% 33% 44% 41% 48% 50% 49% 33% 33% 38% 53% 44% 29% 53% 43% 36% 41% 29% 54% 46% 46% 43% 26% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose181.7851
GSM1296119B_lesional_pre-dose195.9551
GSM1296076C_lesional_pre-dose109.0444
GSM1296092D_lesional_pre-dose91.6442
GSM1296103E_lesional_pre-dose496.0367
GSM1296078F_lesional_pre-dose9.769
GSM1296107G_lesional_pre-dose229.8554
GSM1296109H_lesional_pre-dose797.6975
GSM1296080I_lesional_pre-dose167.6351
GSM1296090J_lesional_pre-dose145.449
GSM1296074K_lesional_pre-dose19054
GSM1296111L_lesional_pre-dose183.2750
GSM1296099M_lesional_pre-dose17150
GSM1296086O_lesional_pre-dose96.8242
GSM1296117P_lesional_pre-dose337.0961
GSM1296113Q_lesional_pre-dose298.8258
GSM1296096R_lesional_pre-dose98.9842
GSM1296105S_lesional_pre-dose223.9553
GSM1296098T_lesional_pre-dose197.5152
GSM1296101U_lesional_pre-dose104.7542
GSM1296121V_lesional_pre-dose213.0853
GSM1296088W_lesional_pre-dose111.1744
GSM1296082X_lesional_pre-dose98.6743
GSM1296115Y_lesional_pre-dose247.1255
GSM1296084Z_lesional_pre-dose113.6943
GSM1296072B_lesional_day8199.5251
GSM1296069L_lesional_day8265.1156
GSM1296071P_lesional_day8284.2457
GSM1296070Y_lesional_day8137.1844
GSM1296073V_lesional_day8210.1254
GSM1296034A_lesional_day15103.8241
GSM1296041G_lesional_day15191.7351
GSM1296035R_lesional_day1583.640
GSM1296038U_lesional_day1575.6937
GSM1296047B_lesional_day15167.8448
GSM1296039E_lesional_day15123.1145
GSM1296042H_lesional_day15150.2346
GSM1296043L_lesional_day15173.7648
GSM1296037M_lesional_day15117.5343
GSM1296046P_lesional_day15170.4148
GSM1296044Q_lesional_day15156.8346
GSM1296045Y_lesional_day15177.9248
GSM1296025C_lesional_day15112.3544
GSM1296033D_lesional_day1571.8637
GSM1296027I_lesional_day158.3110
GSM1296032J_lesional_day155733
GSM1296024K_lesional_day1587.1340
GSM1296031W_lesional_day15154.6447
GSM1296028X_lesional_day1539.2128
GSM1296029Z_lesional_day1562.3635
GSM1296026F_lesional_day1535.4425
GSM1296030O_lesional_day1549.834
GSM1296040S_lesional_day15225.4854
GSM1296036T_lesional_day15204.4452
GSM1296048V_lesional_day15171.1349
GSM1296059A_lesional_day43232.1555
GSM1296066G_lesional_day43111.8441
GSM1296060R_lesional_day4344.630
GSM1296063U_lesional_day4384.3238
GSM1296064E_lesional_day43174.5551
GSM1296067H_lesional_day43205.8951
GSM1296062M_lesional_day43164.7449
GSM1296068Q_lesional_day43252.7154
GSM1296050C_lesional_day4342.3527
GSM1296057D_lesional_day43104.9542
GSM1296052I_lesional_day4346.9332
GSM1296054J_lesional_day4364.4634
GSM1296049K_lesional_day43100.6242
GSM1296055W_lesional_day43218.3753
GSM1296053X_lesional_day4356.1833
GSM1296058Z_lesional_day43138.4147
GSM1296051F_lesional_day4395.9342
GSM1296056O_lesional_day43144.8248
GSM1296065S_lesional_day4384.0638
GSM1296061T_lesional_day43187.9351
GSM1296095A_non-lesional_pre-dose70.8637
GSM1296120B_non-lesional_pre-dose138.0945
GSM1296077C_non-lesional_pre-dose52.6533
GSM1296093D_non-lesional_pre-dose121.9244
GSM1296104E_non-lesional_pre-dose96.1241
GSM1296079F_non-lesional_pre-dose147.2648
GSM1296108G_non-lesional_pre-dose185.9250
GSM1296110H_non-lesional_pre-dose191.1649
GSM1296081I_non-lesional_pre-dose49.9433
GSM1296091J_non-lesional_pre-dose55.0833
GSM1296075K_non-lesional_pre-dose77.7738
GSM1296112L_non-lesional_pre-dose232.5853
GSM1296100M_non-lesional_pre-dose127.5344
GSM1296087O_non-lesional_pre-dose39.2429
GSM1296118P_non-lesional_pre-dose228.6353
GSM1296114Q_non-lesional_pre-dose127.7443
GSM1296097R_non-lesional_pre-dose70.7136
GSM1296106S_non-lesional_pre-dose110.0341
GSM1296102U_non-lesional_pre-dose46.1529
GSM1296122V_non-lesional_pre-dose234.2354
GSM1296089W_non-lesional_pre-dose147.4646
GSM1296083X_non-lesional_pre-dose130.0946
GSM1296116Y_non-lesional_pre-dose136.6743
GSM1296085Z_non-lesional_pre-dose37.1526