ProfileGDS5420 / 229013_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 51% 52% 54% 64% 56% 54% 52% 57% 63% 58% 56% 48% 57% 53% 52% 53% 53% 52% 51% 48% 58% 63% 64% 50% 65% 55% 54% 54% 49% 60% 61% 43% 57% 56% 54% 56% 49% 48% 66% 43% 58% 50% 57% 67% 67% 70% 56% 61% 78% 66% 54% 64% 55% 48% 58% 62% 48% 53% 56% 60% 47% 56% 54% 53% 63% 64% 64% 68% 62% 74% 74% 54% 49% 58% 44% 55% 65% 68% 74% 76% 57% 55% 52% 64% 64% 68% 50% 71% 64% 56% 54% 55% 54% 61% 78% 63% 67% 52% 76% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose181.3951
GSM1296119B_lesional_pre-dose197.0752
GSM1296076C_lesional_pre-dose204.0154
GSM1296092D_lesional_pre-dose371.1264
GSM1296103E_lesional_pre-dose253.1756
GSM1296078F_lesional_pre-dose202.7554
GSM1296107G_lesional_pre-dose208.0652
GSM1296109H_lesional_pre-dose288.1757
GSM1296080I_lesional_pre-dose371.7763
GSM1296090J_lesional_pre-dose264.0758
GSM1296074K_lesional_pre-dose222.1856
GSM1296111L_lesional_pre-dose161.6748
GSM1296099M_lesional_pre-dose268.5957
GSM1296086O_lesional_pre-dose191.653
GSM1296117P_lesional_pre-dose20452
GSM1296113Q_lesional_pre-dose224.4553
GSM1296096R_lesional_pre-dose206.7853
GSM1296105S_lesional_pre-dose209.0652
GSM1296098T_lesional_pre-dose186.8651
GSM1296101U_lesional_pre-dose153.7648
GSM1296121V_lesional_pre-dose279.1258
GSM1296088W_lesional_pre-dose362.763
GSM1296082X_lesional_pre-dose384.4464
GSM1296115Y_lesional_pre-dose183.1850
GSM1296084Z_lesional_pre-dose438.0865
GSM1296072B_lesional_day8251.0255
GSM1296069L_lesional_day8246.6354
GSM1296071P_lesional_day8241.5954
GSM1296070Y_lesional_day8178.0349
GSM1296073V_lesional_day8303.9360
GSM1296034A_lesional_day15353.8561
GSM1296041G_lesional_day15117.9543
GSM1296035R_lesional_day15273.7757
GSM1296038U_lesional_day15247.8556
GSM1296047B_lesional_day15241.1854
GSM1296039E_lesional_day15241.456
GSM1296042H_lesional_day15180.7249
GSM1296043L_lesional_day15168.5748
GSM1296037M_lesional_day15470.6166
GSM1296046P_lesional_day15128.6843
GSM1296044Q_lesional_day15306.0158
GSM1296045Y_lesional_day15200.3450
GSM1296025C_lesional_day15261.9657
GSM1296033D_lesional_day15500.2667
GSM1296027I_lesional_day15475.0267
GSM1296032J_lesional_day15595.7770
GSM1296024K_lesional_day15237.8656
GSM1296031W_lesional_day15343.3461
GSM1296028X_lesional_day15935.5178
GSM1296029Z_lesional_day15472.8666
GSM1296026F_lesional_day15206.5654
GSM1296030O_lesional_day15383.8164
GSM1296040S_lesional_day15236.3355
GSM1296036T_lesional_day15161.8448
GSM1296048V_lesional_day15281.1358
GSM1296059A_lesional_day43358.8262
GSM1296066G_lesional_day43167.9448
GSM1296060R_lesional_day43216.3853
GSM1296063U_lesional_day43248.7256
GSM1296064E_lesional_day43306.3460
GSM1296067H_lesional_day43163.747
GSM1296062M_lesional_day43253.6456
GSM1296068Q_lesional_day43242.8454
GSM1296050C_lesional_day43209.9953
GSM1296057D_lesional_day43398.6763
GSM1296052I_lesional_day43388.2164
GSM1296054J_lesional_day43408.364
GSM1296049K_lesional_day43506.6568
GSM1296055W_lesional_day43365.6162
GSM1296053X_lesional_day43726.5574
GSM1296058Z_lesional_day43753.274
GSM1296051F_lesional_day43211.7354
GSM1296056O_lesional_day4315049
GSM1296065S_lesional_day43292.9558
GSM1296061T_lesional_day43125.5744
GSM1296095A_non-lesional_pre-dose231.6555
GSM1296120B_non-lesional_pre-dose433.1965
GSM1296077C_non-lesional_pre-dose499.468
GSM1296093D_non-lesional_pre-dose734.7274
GSM1296104E_non-lesional_pre-dose803.4476
GSM1296079F_non-lesional_pre-dose254.3557
GSM1296108G_non-lesional_pre-dose252.4955
GSM1296110H_non-lesional_pre-dose226.8552
GSM1296081I_non-lesional_pre-dose406.4364
GSM1296091J_non-lesional_pre-dose396.5564
GSM1296075K_non-lesional_pre-dose471.5168
GSM1296112L_non-lesional_pre-dose204.2850
GSM1296100M_non-lesional_pre-dose63971
GSM1296087O_non-lesional_pre-dose386.3864
GSM1296118P_non-lesional_pre-dose268.6656
GSM1296114Q_non-lesional_pre-dose240.4154
GSM1296097R_non-lesional_pre-dose236.1355
GSM1296106S_non-lesional_pre-dose241.2154
GSM1296102U_non-lesional_pre-dose355.9461
GSM1296122V_non-lesional_pre-dose937.3278
GSM1296089W_non-lesional_pre-dose387.4163
GSM1296083X_non-lesional_pre-dose487.9167
GSM1296116Y_non-lesional_pre-dose221.6952
GSM1296085Z_non-lesional_pre-dose846.1776