ProfileGDS5420 / 228909_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 39% 45% 46% 49% 45% 32% 47% 48% 51% 50% 49% 39% 37% 42% 44% 45% 37% 47% 48% 35% 46% 42% 40% 36% 46% 49% 39% 49% 39% 44% 51% 44% 43% 37% 49% 44% 48% 41% 44% 46% 49% 39% 60% 50% 63% 62% 65% 47% 50% 54% 50% 53% 41% 43% 44% 43% 47% 38% 40% 42% 51% 43% 52% 57% 49% 62% 61% 62% 45% 55% 48% 39% 38% 47% 48% 42% 46% 59% 57% 42% 48% 50% 51% 54% 55% 60% 41% 40% 58% 54% 48% 43% 50% 48% 53% 55% 51% 42% 66% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose84.0839
GSM1296119B_lesional_pre-dose131.1745
GSM1296076C_lesional_pre-dose120.7646
GSM1296092D_lesional_pre-dose141.8549
GSM1296103E_lesional_pre-dose122.1745
GSM1296078F_lesional_pre-dose52.832
GSM1296107G_lesional_pre-dose149.6647
GSM1296109H_lesional_pre-dose161.7148
GSM1296080I_lesional_pre-dose173.2451
GSM1296090J_lesional_pre-dose160.6550
GSM1296074K_lesional_pre-dose136.5549
GSM1296111L_lesional_pre-dose101.5839
GSM1296099M_lesional_pre-dose74.9337
GSM1296086O_lesional_pre-dose98.2142
GSM1296117P_lesional_pre-dose132.4844
GSM1296113Q_lesional_pre-dose150.1745
GSM1296096R_lesional_pre-dose71.1737
GSM1296105S_lesional_pre-dose153.7747
GSM1296098T_lesional_pre-dose154.9548
GSM1296101U_lesional_pre-dose66.9635
GSM1296121V_lesional_pre-dose139.9746
GSM1296088W_lesional_pre-dose97.9342
GSM1296082X_lesional_pre-dose80.4240
GSM1296115Y_lesional_pre-dose76.8536
GSM1296084Z_lesional_pre-dose135.6546
GSM1296072B_lesional_day8172.3549
GSM1296069L_lesional_day8103.0539
GSM1296071P_lesional_day8185.2549
GSM1296070Y_lesional_day8100.3239
GSM1296073V_lesional_day8118.2844
GSM1296034A_lesional_day15196.9651
GSM1296041G_lesional_day15127.9344
GSM1296035R_lesional_day15104.4943
GSM1296038U_lesional_day1575.7937
GSM1296047B_lesional_day15174.2349
GSM1296039E_lesional_day15115.3444
GSM1296042H_lesional_day15168.4248
GSM1296043L_lesional_day15117.9641
GSM1296037M_lesional_day15128.6744
GSM1296046P_lesional_day15154.5746
GSM1296044Q_lesional_day15188.6549
GSM1296045Y_lesional_day15105.0739
GSM1296025C_lesional_day15309.7460
GSM1296033D_lesional_day15166.4450
GSM1296027I_lesional_day15356.3363
GSM1296032J_lesional_day15366.862
GSM1296024K_lesional_day15419.0165
GSM1296031W_lesional_day15150.3747
GSM1296028X_lesional_day15169.1650
GSM1296029Z_lesional_day15226.0854
GSM1296026F_lesional_day15166.1750
GSM1296030O_lesional_day15180.4453
GSM1296040S_lesional_day15100.7441
GSM1296036T_lesional_day15120.7843
GSM1296048V_lesional_day15124.1144
GSM1296059A_lesional_day43104.6343
GSM1296066G_lesional_day43154.7447
GSM1296060R_lesional_day4380.0538
GSM1296063U_lesional_day4394.0740
GSM1296064E_lesional_day4310042
GSM1296067H_lesional_day43204.7851
GSM1296062M_lesional_day43113.1343
GSM1296068Q_lesional_day43217.1852
GSM1296050C_lesional_day43258.7757
GSM1296057D_lesional_day43158.5749
GSM1296052I_lesional_day43348.0562
GSM1296054J_lesional_day43345.7961
GSM1296049K_lesional_day43349.9362
GSM1296055W_lesional_day43138.3545
GSM1296053X_lesional_day43231.6355
GSM1296058Z_lesional_day43145.1548
GSM1296051F_lesional_day4379.7839
GSM1296056O_lesional_day4375.0838
GSM1296065S_lesional_day43151.2847
GSM1296061T_lesional_day43155.6248
GSM1296095A_non-lesional_pre-dose97.4742
GSM1296120B_non-lesional_pre-dose146.8146
GSM1296077C_non-lesional_pre-dose296.3959
GSM1296093D_non-lesional_pre-dose280.5757
GSM1296104E_non-lesional_pre-dose107.3542
GSM1296079F_non-lesional_pre-dose146.748
GSM1296108G_non-lesional_pre-dose180.150
GSM1296110H_non-lesional_pre-dose211.2851
GSM1296081I_non-lesional_pre-dose205.5354
GSM1296091J_non-lesional_pre-dose225.1855
GSM1296075K_non-lesional_pre-dose290.2760
GSM1296112L_non-lesional_pre-dose124.7241
GSM1296100M_non-lesional_pre-dose96.440
GSM1296087O_non-lesional_pre-dose254.7158
GSM1296118P_non-lesional_pre-dose242.4954
GSM1296114Q_non-lesional_pre-dose176.3848
GSM1296097R_non-lesional_pre-dose113.3243
GSM1296106S_non-lesional_pre-dose184.5850
GSM1296102U_non-lesional_pre-dose164.2648
GSM1296122V_non-lesional_pre-dose222.5353
GSM1296089W_non-lesional_pre-dose249.5355
GSM1296083X_non-lesional_pre-dose180.2751
GSM1296116Y_non-lesional_pre-dose128.9242
GSM1296085Z_non-lesional_pre-dose445.4666