ProfileGDS5420 / 228908_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 48% 54% 59% 61% 49% 48% 59% 51% 52% 62% 60% 54% 54% 58% 53% 54% 57% 62% 59% 55% 46% 56% 52% 47% 58% 60% 51% 65% 54% 45% 59% 56% 57% 52% 62% 55% 56% 55% 59% 60% 61% 57% 74% 63% 72% 68% 68% 65% 66% 66% 52% 66% 53% 56% 54% 51% 58% 59% 56% 49% 65% 62% 63% 71% 68% 70% 73% 71% 61% 68% 59% 51% 54% 66% 68% 55% 55% 73% 67% 56% 63% 64% 64% 68% 65% 64% 57% 56% 72% 63% 62% 58% 64% 61% 60% 67% 56% 58% 65% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose156.7548
GSM1296119B_lesional_pre-dose222.9854
GSM1296076C_lesional_pre-dose275.259
GSM1296092D_lesional_pre-dose318.7861
GSM1296103E_lesional_pre-dose158.3149
GSM1296078F_lesional_pre-dose134.1948
GSM1296107G_lesional_pre-dose295.5459
GSM1296109H_lesional_pre-dose196.4151
GSM1296080I_lesional_pre-dose185.1552
GSM1296090J_lesional_pre-dose342.2462
GSM1296074K_lesional_pre-dose284.3760
GSM1296111L_lesional_pre-dose228.5154
GSM1296099M_lesional_pre-dose223.3354
GSM1296086O_lesional_pre-dose263.558
GSM1296117P_lesional_pre-dose222.9153
GSM1296113Q_lesional_pre-dose243.954
GSM1296096R_lesional_pre-dose262.2257
GSM1296105S_lesional_pre-dose368.8162
GSM1296098T_lesional_pre-dose310.6659
GSM1296101U_lesional_pre-dose246.1155
GSM1296121V_lesional_pre-dose142.8646
GSM1296088W_lesional_pre-dose244.4556
GSM1296082X_lesional_pre-dose172.4452
GSM1296115Y_lesional_pre-dose150.7747
GSM1296084Z_lesional_pre-dose285.6358
GSM1296072B_lesional_day8319.0160
GSM1296069L_lesional_day8202.7351
GSM1296071P_lesional_day8452.7265
GSM1296070Y_lesional_day8235.0654
GSM1296073V_lesional_day8126.1645
GSM1296034A_lesional_day15325.0559
GSM1296041G_lesional_day15252.956
GSM1296035R_lesional_day1526157
GSM1296038U_lesional_day15199.9752
GSM1296047B_lesional_day15362.8162
GSM1296039E_lesional_day15235.3455
GSM1296042H_lesional_day15269.0356
GSM1296043L_lesional_day15262.5955
GSM1296037M_lesional_day15303.5359
GSM1296046P_lesional_day15332.7660
GSM1296044Q_lesional_day15362.8161
GSM1296045Y_lesional_day15279.8557
GSM1296025C_lesional_day15742.3974
GSM1296033D_lesional_day15385.9263
GSM1296027I_lesional_day15656.9772
GSM1296032J_lesional_day15536.8568
GSM1296024K_lesional_day15524.6668
GSM1296031W_lesional_day15430.0365
GSM1296028X_lesional_day15466.0866
GSM1296029Z_lesional_day15455.6966
GSM1296026F_lesional_day15189.9652
GSM1296030O_lesional_day15441.9866
GSM1296040S_lesional_day15212.3353
GSM1296036T_lesional_day15260.5556
GSM1296048V_lesional_day15222.3754
GSM1296059A_lesional_day43178.6351
GSM1296066G_lesional_day43288.6558
GSM1296060R_lesional_day43297.359
GSM1296063U_lesional_day43250.2356
GSM1296064E_lesional_day43158.9949
GSM1296067H_lesional_day43438.4565
GSM1296062M_lesional_day43378.6662
GSM1296068Q_lesional_day43405.1763
GSM1296050C_lesional_day43605.671
GSM1296057D_lesional_day43508.3968
GSM1296052I_lesional_day43569.8170
GSM1296054J_lesional_day43684.9173
GSM1296049K_lesional_day43603.2371
GSM1296055W_lesional_day43340.8961
GSM1296053X_lesional_day43514.5268
GSM1296058Z_lesional_day43294.2459
GSM1296051F_lesional_day43168.7351
GSM1296056O_lesional_day43208.4754
GSM1296065S_lesional_day43445.3166
GSM1296061T_lesional_day43528.868
GSM1296095A_non-lesional_pre-dose226.6555
GSM1296120B_non-lesional_pre-dose253.7855
GSM1296077C_non-lesional_pre-dose698.9573
GSM1296093D_non-lesional_pre-dose494.7767
GSM1296104E_non-lesional_pre-dose254.5656
GSM1296079F_non-lesional_pre-dose363.6363
GSM1296108G_non-lesional_pre-dose398.9664
GSM1296110H_non-lesional_pre-dose425.2764
GSM1296081I_non-lesional_pre-dose493.5768
GSM1296091J_non-lesional_pre-dose424.5865
GSM1296075K_non-lesional_pre-dose368.7964
GSM1296112L_non-lesional_pre-dose293.4357
GSM1296100M_non-lesional_pre-dose267.1156
GSM1296087O_non-lesional_pre-dose645.1672
GSM1296118P_non-lesional_pre-dose408.7463
GSM1296114Q_non-lesional_pre-dose366.5462
GSM1296097R_non-lesional_pre-dose284.9358
GSM1296106S_non-lesional_pre-dose412.1764
GSM1296102U_non-lesional_pre-dose350.0761
GSM1296122V_non-lesional_pre-dose322.8660
GSM1296089W_non-lesional_pre-dose497.8767
GSM1296083X_non-lesional_pre-dose253.7456
GSM1296116Y_non-lesional_pre-dose297.7458
GSM1296085Z_non-lesional_pre-dose437.7865