ProfileGDS5420 / 228849_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 48% 46% 54% 50% 38% 54% 43% 40% 61% 52% 44% 42% 51% 50% 42% 53% 49% 80% 33% 49% 45% 50% 41% 39% 56% 49% 51% 60% 47% 40% 56% 37% 43% 55% 50% 40% 42% 57% 64% 50% 44% 49% 62% 59% 62% 72% 70% 60% 72% 60% 58% 55% 57% 48% 47% 42% 46% 50% 56% 43% 47% 61% 54% 69% 66% 68% 65% 65% 55% 67% 56% 67% 50% 61% 42% 46% 49% 63% 66% 55% 75% 49% 40% 64% 61% 64% 54% 68% 67% 56% 48% 52% 62% 54% 60% 59% 68% 49% 66% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose150.6848
GSM1296119B_lesional_pre-dose141.9846
GSM1296076C_lesional_pre-dose203.9654
GSM1296092D_lesional_pre-dose159.250
GSM1296103E_lesional_pre-dose75.4538
GSM1296078F_lesional_pre-dose197.154
GSM1296107G_lesional_pre-dose120.0743
GSM1296109H_lesional_pre-dose100.9240
GSM1296080I_lesional_pre-dose332.761
GSM1296090J_lesional_pre-dose181.452
GSM1296074K_lesional_pre-dose101.444
GSM1296111L_lesional_pre-dose119.9242
GSM1296099M_lesional_pre-dose183.6851
GSM1296086O_lesional_pre-dose163.8750
GSM1296117P_lesional_pre-dose120.1842
GSM1296113Q_lesional_pre-dose233.5953
GSM1296096R_lesional_pre-dose160.2349
GSM1296105S_lesional_pre-dose1063.8180
GSM1296098T_lesional_pre-dose65.2133
GSM1296101U_lesional_pre-dose165.5649
GSM1296121V_lesional_pre-dose129.0145
GSM1296088W_lesional_pre-dose170.5950
GSM1296082X_lesional_pre-dose87.0741
GSM1296115Y_lesional_pre-dose94.3439
GSM1296084Z_lesional_pre-dose254.7256
GSM1296072B_lesional_day8170.249
GSM1296069L_lesional_day8200.5551
GSM1296071P_lesional_day8332.5260
GSM1296070Y_lesional_day8161.7647
GSM1296073V_lesional_day895.2640
GSM1296034A_lesional_day15272.1356
GSM1296041G_lesional_day1585.2237
GSM1296035R_lesional_day15107.1843
GSM1296038U_lesional_day15234.4955
GSM1296047B_lesional_day15182.0350
GSM1296039E_lesional_day1587.2440
GSM1296042H_lesional_day15122.6142
GSM1296043L_lesional_day15278.1957
GSM1296037M_lesional_day1540564
GSM1296046P_lesional_day15193.7150
GSM1296044Q_lesional_day15141.3344
GSM1296045Y_lesional_day15181.3849
GSM1296025C_lesional_day15347.6362
GSM1296033D_lesional_day15295.0459
GSM1296027I_lesional_day15341.2362
GSM1296032J_lesional_day15651.8972
GSM1296024K_lesional_day15564.3770
GSM1296031W_lesional_day15324.7660
GSM1296028X_lesional_day15655.7672
GSM1296029Z_lesional_day15311.5860
GSM1296026F_lesional_day15276.7658
GSM1296030O_lesional_day15208.155
GSM1296040S_lesional_day15263.2357
GSM1296036T_lesional_day15167.0448
GSM1296048V_lesional_day15148.9947
GSM1296059A_lesional_day43101.2642
GSM1296066G_lesional_day43147.3646
GSM1296060R_lesional_day43172.9250
GSM1296063U_lesional_day43247.6456
GSM1296064E_lesional_day43103.2443
GSM1296067H_lesional_day43162.9147
GSM1296062M_lesional_day43348.4361
GSM1296068Q_lesional_day43254.7954
GSM1296050C_lesional_day43539.1869
GSM1296057D_lesional_day43463.2166
GSM1296052I_lesional_day43490.968
GSM1296054J_lesional_day43448.4565
GSM1296049K_lesional_day43424.7165
GSM1296055W_lesional_day43247.4255
GSM1296053X_lesional_day43486.9867
GSM1296058Z_lesional_day43248.3356
GSM1296051F_lesional_day43471.9867
GSM1296056O_lesional_day43159.2950
GSM1296065S_lesional_day43347.8561
GSM1296061T_lesional_day43105.4242
GSM1296095A_non-lesional_pre-dose130.6246
GSM1296120B_non-lesional_pre-dose180.9749
GSM1296077C_non-lesional_pre-dose361.1863
GSM1296093D_non-lesional_pre-dose46266
GSM1296104E_non-lesional_pre-dose244.6155
GSM1296079F_non-lesional_pre-dose781.7375
GSM1296108G_non-lesional_pre-dose174.9849
GSM1296110H_non-lesional_pre-dose109.8740
GSM1296081I_non-lesional_pre-dose398.8664
GSM1296091J_non-lesional_pre-dose329.5961
GSM1296075K_non-lesional_pre-dose371.6864
GSM1296112L_non-lesional_pre-dose247.4854
GSM1296100M_non-lesional_pre-dose529.8468
GSM1296087O_non-lesional_pre-dose451.367
GSM1296118P_non-lesional_pre-dose280.256
GSM1296114Q_non-lesional_pre-dose170.2848
GSM1296097R_non-lesional_pre-dose193.8652
GSM1296106S_non-lesional_pre-dose369.2962
GSM1296102U_non-lesional_pre-dose233.7554
GSM1296122V_non-lesional_pre-dose320.2760
GSM1296089W_non-lesional_pre-dose311.3959
GSM1296083X_non-lesional_pre-dose530.0568
GSM1296116Y_non-lesional_pre-dose191.449
GSM1296085Z_non-lesional_pre-dose454.8466