ProfileGDS5420 / 228435_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 73% 94% 94% 93% 86% 94% 91% 84% 67% 93% 90% 94% 89% 89% 92% 94% 90% 81% 68% 82% 93% 82% 94% 95% 85% 94% 90% 90% 94% 92% 62% 94% 88% 89% 92% 94% 92% 91% 85% 94% 94% 94% 65% 89% 81% 83% 60% 85% 86% 77% 75% 80% 84% 69% 93% 84% 93% 90% 93% 94% 85% 77% 92% 86% 92% 81% 78% 71% 89% 70% 88% 90% 91% 94% 63% 92% 93% 74% 75% 94% 78% 93% 87% 72% 95% 89% 90% 89% 87% 91% 94% 90% 89% 78% 87% 88% 71% 93% 87% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose696.773
GSM1296119B_lesional_pre-dose3040.8994
GSM1296076C_lesional_pre-dose3576.0394
GSM1296092D_lesional_pre-dose3045.0693
GSM1296103E_lesional_pre-dose1545.4286
GSM1296078F_lesional_pre-dose3557.5794
GSM1296107G_lesional_pre-dose2456.6991
GSM1296109H_lesional_pre-dose1344.9384
GSM1296080I_lesional_pre-dose472.5967
GSM1296090J_lesional_pre-dose3053.3793
GSM1296074K_lesional_pre-dose2477.7390
GSM1296111L_lesional_pre-dose2942.894
GSM1296099M_lesional_pre-dose1935.4789
GSM1296086O_lesional_pre-dose2077.5889
GSM1296117P_lesional_pre-dose2567.7692
GSM1296113Q_lesional_pre-dose2768.4694
GSM1296096R_lesional_pre-dose2099.0590
GSM1296105S_lesional_pre-dose1118.4681
GSM1296098T_lesional_pre-dose509.168
GSM1296101U_lesional_pre-dose1187.8682
GSM1296121V_lesional_pre-dose2753.5693
GSM1296088W_lesional_pre-dose1205.4982
GSM1296082X_lesional_pre-dose3709.1794
GSM1296115Y_lesional_pre-dose3367.7995
GSM1296084Z_lesional_pre-dose1512.4485
GSM1296072B_lesional_day82875.8194
GSM1296069L_lesional_day82059.3290
GSM1296071P_lesional_day81905.3890
GSM1296070Y_lesional_day82852.2794
GSM1296073V_lesional_day82646.2392
GSM1296034A_lesional_day15380.0862
GSM1296041G_lesional_day153312.8294
GSM1296035R_lesional_day151871.1288
GSM1296038U_lesional_day152087.689
GSM1296047B_lesional_day152438.1492
GSM1296039E_lesional_day153712.8694
GSM1296042H_lesional_day152429.4692
GSM1296043L_lesional_day152221.7891
GSM1296037M_lesional_day151462.9985
GSM1296046P_lesional_day152726.8694
GSM1296044Q_lesional_day152714.5994
GSM1296045Y_lesional_day152846.694
GSM1296025C_lesional_day15434.365
GSM1296033D_lesional_day151922.2789
GSM1296027I_lesional_day151200.181
GSM1296032J_lesional_day151298.2183
GSM1296024K_lesional_day15320.1960
GSM1296031W_lesional_day151458.1185
GSM1296028X_lesional_day151616.1986
GSM1296029Z_lesional_day15920.677
GSM1296026F_lesional_day15786.4275
GSM1296030O_lesional_day151109.4280
GSM1296040S_lesional_day151352.1884
GSM1296036T_lesional_day15572.8469
GSM1296048V_lesional_day152760.7593
GSM1296059A_lesional_day431413.1284
GSM1296066G_lesional_day432710.7593
GSM1296060R_lesional_day432090.2590
GSM1296063U_lesional_day432900.6893
GSM1296064E_lesional_day433725.7694
GSM1296067H_lesional_day431420.785
GSM1296062M_lesional_day43906.3777
GSM1296068Q_lesional_day432301.1892
GSM1296050C_lesional_day431611.8386
GSM1296057D_lesional_day432529.9792
GSM1296052I_lesional_day431170.5681
GSM1296054J_lesional_day43966.2978
GSM1296049K_lesional_day43617.771
GSM1296055W_lesional_day431938.789
GSM1296053X_lesional_day4357770
GSM1296058Z_lesional_day431877.9488
GSM1296051F_lesional_day432242.8190
GSM1296056O_lesional_day432436.7891
GSM1296065S_lesional_day432812.8494
GSM1296061T_lesional_day43396.2463
GSM1296095A_non-lesional_pre-dose2626.4992
GSM1296120B_non-lesional_pre-dose2808.3693
GSM1296077C_non-lesional_pre-dose714.1674
GSM1296093D_non-lesional_pre-dose778.3575
GSM1296104E_non-lesional_pre-dose3553.2894
GSM1296079F_non-lesional_pre-dose956.7878
GSM1296108G_non-lesional_pre-dose2671.5393
GSM1296110H_non-lesional_pre-dose1556.1787
GSM1296081I_non-lesional_pre-dose633.8572
GSM1296091J_non-lesional_pre-dose3416.0495
GSM1296075K_non-lesional_pre-dose2023.7689
GSM1296112L_non-lesional_pre-dose1889.6790
GSM1296100M_non-lesional_pre-dose1927.3889
GSM1296087O_non-lesional_pre-dose1843.987
GSM1296118P_non-lesional_pre-dose2157.591
GSM1296114Q_non-lesional_pre-dose2915.4694
GSM1296097R_non-lesional_pre-dose2230.0190
GSM1296106S_non-lesional_pre-dose1958.4689
GSM1296102U_non-lesional_pre-dose933.7478
GSM1296122V_non-lesional_pre-dose1648.2187
GSM1296089W_non-lesional_pre-dose1727.6288
GSM1296083X_non-lesional_pre-dose630.8871
GSM1296116Y_non-lesional_pre-dose2632.3193
GSM1296085Z_non-lesional_pre-dose1675.4987