ProfileGDS5420 / 228064_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 76% 57% 61% 74% 77% 62% 52% 71% 87% 70% 65% 53% 68% 71% 57% 53% 67% 76% 83% 72% 58% 72% 67% 55% 72% 56% 53% 61% 58% 52% 84% 52% 70% 64% 57% 59% 58% 57% 78% 54% 55% 59% 75% 80% 83% 80% 76% 79% 81% 84% 66% 80% 82% 81% 58% 72% 52% 71% 60% 58% 66% 82% 57% 62% 71% 85% 82% 74% 66% 85% 76% 63% 69% 69% 85% 58% 57% 69% 87% 55% 69% 53% 62% 92% 72% 63% 60% 79% 78% 61% 55% 66% 73% 73% 59% 69% 89% 59% 88% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose832.1276
GSM1296119B_lesional_pre-dose275.4657
GSM1296076C_lesional_pre-dose306.8761
GSM1296092D_lesional_pre-dose718.1574
GSM1296103E_lesional_pre-dose861.4877
GSM1296078F_lesional_pre-dose316.762
GSM1296107G_lesional_pre-dose201.4552
GSM1296109H_lesional_pre-dose627.7271
GSM1296080I_lesional_pre-dose1777.0787
GSM1296090J_lesional_pre-dose552.6570
GSM1296074K_lesional_pre-dose388.9465
GSM1296111L_lesional_pre-dose220.0453
GSM1296099M_lesional_pre-dose512.8368
GSM1296086O_lesional_pre-dose599.1671
GSM1296117P_lesional_pre-dose276.0657
GSM1296113Q_lesional_pre-dose235.2653
GSM1296096R_lesional_pre-dose475.8967
GSM1296105S_lesional_pre-dose848.6876
GSM1296098T_lesional_pre-dose1304.8383
GSM1296101U_lesional_pre-dose660.5372
GSM1296121V_lesional_pre-dose284.8658
GSM1296088W_lesional_pre-dose670.472
GSM1296082X_lesional_pre-dose470.6267
GSM1296115Y_lesional_pre-dose23655
GSM1296084Z_lesional_pre-dose651.8172
GSM1296072B_lesional_day8261.3256
GSM1296069L_lesional_day8222.9353
GSM1296071P_lesional_day8356.0461
GSM1296070Y_lesional_day8300.8258
GSM1296073V_lesional_day818752
GSM1296034A_lesional_day151333.5784
GSM1296041G_lesional_day15198.7952
GSM1296035R_lesional_day15580.8670
GSM1296038U_lesional_day15397.564
GSM1296047B_lesional_day15277.2757
GSM1296039E_lesional_day15296.4559
GSM1296042H_lesional_day15286.5958
GSM1296043L_lesional_day15291.2157
GSM1296037M_lesional_day15955.5578
GSM1296046P_lesional_day15240.9154
GSM1296044Q_lesional_day15253.3155
GSM1296045Y_lesional_day15323.659
GSM1296025C_lesional_day15770.0175
GSM1296033D_lesional_day151069.6580
GSM1296027I_lesional_day151352.5283
GSM1296032J_lesional_day151065.4580
GSM1296024K_lesional_day15851.1476
GSM1296031W_lesional_day151004.5279
GSM1296028X_lesional_day151166.4881
GSM1296029Z_lesional_day151338.0184
GSM1296026F_lesional_day15429.6766
GSM1296030O_lesional_day151111.0580
GSM1296040S_lesional_day151215.7282
GSM1296036T_lesional_day151119.7781
GSM1296048V_lesional_day15289.4358
GSM1296059A_lesional_day43639.8472
GSM1296066G_lesional_day43213.3752
GSM1296060R_lesional_day43631.2171
GSM1296063U_lesional_day43317.7760
GSM1296064E_lesional_day43271.2758
GSM1296067H_lesional_day43461.5766
GSM1296062M_lesional_day431236.9382
GSM1296068Q_lesional_day43290.4757
GSM1296050C_lesional_day43351.3662
GSM1296057D_lesional_day43633.0171
GSM1296052I_lesional_day431491.5685
GSM1296054J_lesional_day431191.2682
GSM1296049K_lesional_day43712.3974
GSM1296055W_lesional_day43455.7866
GSM1296053X_lesional_day431501.4385
GSM1296058Z_lesional_day43822.7176
GSM1296051F_lesional_day43365.2463
GSM1296056O_lesional_day43540.9369
GSM1296065S_lesional_day43530.6269
GSM1296061T_lesional_day431432.9285
GSM1296095A_non-lesional_pre-dose270.9158
GSM1296120B_non-lesional_pre-dose273.2557
GSM1296077C_non-lesional_pre-dose524.7669
GSM1296093D_non-lesional_pre-dose1607.2187
GSM1296104E_non-lesional_pre-dose241.655
GSM1296079F_non-lesional_pre-dose537.6169
GSM1296108G_non-lesional_pre-dose219.8353
GSM1296110H_non-lesional_pre-dose373.5762
GSM1296081I_non-lesional_pre-dose2751.6792
GSM1296091J_non-lesional_pre-dose665.2672
GSM1296075K_non-lesional_pre-dose359.663
GSM1296112L_non-lesional_pre-dose349.5860
GSM1296100M_non-lesional_pre-dose981.3979
GSM1296087O_non-lesional_pre-dose967.3978
GSM1296118P_non-lesional_pre-dose357.2261
GSM1296114Q_non-lesional_pre-dose254.8855
GSM1296097R_non-lesional_pre-dose454.9666
GSM1296106S_non-lesional_pre-dose697.4273
GSM1296102U_non-lesional_pre-dose696.2373
GSM1296122V_non-lesional_pre-dose314.759
GSM1296089W_non-lesional_pre-dose549.9769
GSM1296083X_non-lesional_pre-dose1937.2989
GSM1296116Y_non-lesional_pre-dose314.7659
GSM1296085Z_non-lesional_pre-dose1777.4588