ProfileGDS5420 / 227699_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 50% 52% 59% 55% 46% 58% 52% 43% 59% 49% 63% 45% 49% 61% 49% 52% 51% 51% 51% 47% 54% 54% 60% 50% 59% 46% 51% 49% 47% 51% 44% 50% 51% 46% 48% 52% 48% 50% 42% 50% 50% 50% 56% 56% 57% 49% 62% 52% 57% 62% 56% 58% 46% 44% 52% 46% 51% 57% 51% 50% 54% 56% 55% 60% 54% 58% 50% 58% 53% 59% 51% 60% 53% 54% 52% 51% 49% 58% 45% 51% 59% 48% 49% 63% 46% 60% 43% 42% 60% 45% 49% 54% 54% 49% 51% 48% 58% 50% 54% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose177.3150
GSM1296119B_lesional_pre-dose197.1852
GSM1296076C_lesional_pre-dose267.0759
GSM1296092D_lesional_pre-dose215.9655
GSM1296103E_lesional_pre-dose135.9946
GSM1296078F_lesional_pre-dose254.0558
GSM1296107G_lesional_pre-dose207.1452
GSM1296109H_lesional_pre-dose123.2143
GSM1296080I_lesional_pre-dose285.5459
GSM1296090J_lesional_pre-dose146.2949
GSM1296074K_lesional_pre-dose340.2763
GSM1296111L_lesional_pre-dose138.3245
GSM1296099M_lesional_pre-dose167.7249
GSM1296086O_lesional_pre-dose317.1161
GSM1296117P_lesional_pre-dose178.4149
GSM1296113Q_lesional_pre-dose223.8552
GSM1296096R_lesional_pre-dose176.6951
GSM1296105S_lesional_pre-dose195.5151
GSM1296098T_lesional_pre-dose183.9151
GSM1296101U_lesional_pre-dose144.5247
GSM1296121V_lesional_pre-dose228.0354
GSM1296088W_lesional_pre-dose209.6954
GSM1296082X_lesional_pre-dose291.0960
GSM1296115Y_lesional_pre-dose176.9450
GSM1296084Z_lesional_pre-dose304.6359
GSM1296072B_lesional_day8148.7346
GSM1296069L_lesional_day8208.1751
GSM1296071P_lesional_day8187.8849
GSM1296070Y_lesional_day8168.0247
GSM1296073V_lesional_day8178.1551
GSM1296034A_lesional_day1512844
GSM1296041G_lesional_day15179.2650
GSM1296035R_lesional_day15179.4651
GSM1296038U_lesional_day15129.9846
GSM1296047B_lesional_day15166.6748
GSM1296039E_lesional_day15195.9152
GSM1296042H_lesional_day15172.5548
GSM1296043L_lesional_day15191.1950
GSM1296037M_lesional_day15109.8242
GSM1296046P_lesional_day15192.3150
GSM1296044Q_lesional_day15197.1750
GSM1296045Y_lesional_day15195.8350
GSM1296025C_lesional_day15239.8556
GSM1296033D_lesional_day15245.5556
GSM1296027I_lesional_day15247.5457
GSM1296032J_lesional_day15167.6749
GSM1296024K_lesional_day15347.0862
GSM1296031W_lesional_day15208.8152
GSM1296028X_lesional_day15261.7157
GSM1296029Z_lesional_day15364.6262
GSM1296026F_lesional_day15243.1956
GSM1296030O_lesional_day15268.3558
GSM1296040S_lesional_day15134.7446
GSM1296036T_lesional_day15128.3844
GSM1296048V_lesional_day15196.4652
GSM1296059A_lesional_day43127.8646
GSM1296066G_lesional_day43194.2251
GSM1296060R_lesional_day43264.8557
GSM1296063U_lesional_day43185.7151
GSM1296064E_lesional_day43168.3950
GSM1296067H_lesional_day43247.0654
GSM1296062M_lesional_day43254.4656
GSM1296068Q_lesional_day43261.5355
GSM1296050C_lesional_day43314.4760
GSM1296057D_lesional_day43216.8454
GSM1296052I_lesional_day43273.5558
GSM1296054J_lesional_day43180.7550
GSM1296049K_lesional_day43286.5658
GSM1296055W_lesional_day43214.6853
GSM1296053X_lesional_day43306.0959
GSM1296058Z_lesional_day43181.5851
GSM1296051F_lesional_day43292.4560
GSM1296056O_lesional_day43191.1653
GSM1296065S_lesional_day43223.1954
GSM1296061T_lesional_day43207.1452
GSM1296095A_non-lesional_pre-dose18451
GSM1296120B_non-lesional_pre-dose175.7449
GSM1296077C_non-lesional_pre-dose272.3858
GSM1296093D_non-lesional_pre-dose134.0745
GSM1296104E_non-lesional_pre-dose184.6651
GSM1296079F_non-lesional_pre-dose283.0559
GSM1296108G_non-lesional_pre-dose167.9348
GSM1296110H_non-lesional_pre-dose181.7549
GSM1296081I_non-lesional_pre-dose380.8363
GSM1296091J_non-lesional_pre-dose126.3446
GSM1296075K_non-lesional_pre-dose289.4660
GSM1296112L_non-lesional_pre-dose139.8543
GSM1296100M_non-lesional_pre-dose108.2742
GSM1296087O_non-lesional_pre-dose297.7860
GSM1296118P_non-lesional_pre-dose147.7445
GSM1296114Q_non-lesional_pre-dose186.4349
GSM1296097R_non-lesional_pre-dose220.0754
GSM1296106S_non-lesional_pre-dose236.3754
GSM1296102U_non-lesional_pre-dose180.4149
GSM1296122V_non-lesional_pre-dose196.751
GSM1296089W_non-lesional_pre-dose159.648
GSM1296083X_non-lesional_pre-dose285.2458
GSM1296116Y_non-lesional_pre-dose202.4450
GSM1296085Z_non-lesional_pre-dose217.2354