ProfileGDS5420 / 227535_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 64% 77% 83% 82% 71% 83% 77% 69% 59% 83% 82% 78% 79% 82% 79% 74% 78% 70% 58% 72% 75% 74% 84% 80% 71% 74% 77% 72% 76% 78% 43% 79% 74% 79% 73% 85% 74% 74% 73% 75% 74% 76% 58% 74% 71% 71% 51% 71% 72% 67% 67% 72% 66% 59% 76% 71% 77% 78% 84% 86% 68% 67% 75% 75% 77% 72% 61% 58% 78% 55% 71% 79% 78% 82% 51% 82% 74% 64% 50% 86% 66% 75% 65% 55% 81% 80% 71% 75% 73% 72% 71% 79% 74% 69% 74% 75% 57% 74% 64% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose408.564
GSM1296119B_lesional_pre-dose870.3377
GSM1296076C_lesional_pre-dose1316.9383
GSM1296092D_lesional_pre-dose1298.382
GSM1296103E_lesional_pre-dose616.4371
GSM1296078F_lesional_pre-dose1382.1883
GSM1296107G_lesional_pre-dose877.7277
GSM1296109H_lesional_pre-dose546.9469
GSM1296080I_lesional_pre-dose281.0659
GSM1296090J_lesional_pre-dose1292.9683
GSM1296074K_lesional_pre-dose1255.4582
GSM1296111L_lesional_pre-dose947.4778
GSM1296099M_lesional_pre-dose1027.7379
GSM1296086O_lesional_pre-dose1265.3582
GSM1296117P_lesional_pre-dose959.4679
GSM1296113Q_lesional_pre-dose737.1174
GSM1296096R_lesional_pre-dose941.7178
GSM1296105S_lesional_pre-dose573.6970
GSM1296098T_lesional_pre-dose288.5958
GSM1296101U_lesional_pre-dose658.1672
GSM1296121V_lesional_pre-dose784.5375
GSM1296088W_lesional_pre-dose756.774
GSM1296082X_lesional_pre-dose1434.4484
GSM1296115Y_lesional_pre-dose1036.4780
GSM1296084Z_lesional_pre-dose596.8871
GSM1296072B_lesional_day8730.8674
GSM1296069L_lesional_day8883.6777
GSM1296071P_lesional_day8640.2372
GSM1296070Y_lesional_day8792.5376
GSM1296073V_lesional_day8928.8678
GSM1296034A_lesional_day15123.7843
GSM1296041G_lesional_day15951.0779
GSM1296035R_lesional_day15761.8974
GSM1296038U_lesional_day15999.1279
GSM1296047B_lesional_day15691.3673
GSM1296039E_lesional_day151460.785
GSM1296042H_lesional_day15739.7174
GSM1296043L_lesional_day15735.9174
GSM1296037M_lesional_day15674.3273
GSM1296046P_lesional_day15792.8175
GSM1296044Q_lesional_day15722.5674
GSM1296045Y_lesional_day15814.0676
GSM1296025C_lesional_day15266.8758
GSM1296033D_lesional_day15747.3374
GSM1296027I_lesional_day15590.0871
GSM1296032J_lesional_day15608.1371
GSM1296024K_lesional_day15178.751
GSM1296031W_lesional_day15604.3871
GSM1296028X_lesional_day15638.2872
GSM1296029Z_lesional_day15499.9867
GSM1296026F_lesional_day15458.367
GSM1296030O_lesional_day15653.3472
GSM1296040S_lesional_day15469.4866
GSM1296036T_lesional_day15318.9359
GSM1296048V_lesional_day15804.5476
GSM1296059A_lesional_day43626.2471
GSM1296066G_lesional_day43850.5677
GSM1296060R_lesional_day43924.578
GSM1296063U_lesional_day431417.2984
GSM1296064E_lesional_day431640.2286
GSM1296067H_lesional_day43526.0168
GSM1296062M_lesional_day43492.1367
GSM1296068Q_lesional_day43762.6575
GSM1296050C_lesional_day43761.6875
GSM1296057D_lesional_day43881.3477
GSM1296052I_lesional_day43643.4972
GSM1296054J_lesional_day43345.1861
GSM1296049K_lesional_day43272.7658
GSM1296055W_lesional_day43907.7878
GSM1296053X_lesional_day43241.6255
GSM1296058Z_lesional_day43623.6671
GSM1296051F_lesional_day431015.0779
GSM1296056O_lesional_day43934.5978
GSM1296065S_lesional_day431220.1582
GSM1296061T_lesional_day43194.0551
GSM1296095A_non-lesional_pre-dose1230.1282
GSM1296120B_non-lesional_pre-dose706.3774
GSM1296077C_non-lesional_pre-dose394.8864
GSM1296093D_non-lesional_pre-dose186.5550
GSM1296104E_non-lesional_pre-dose1639.0786
GSM1296079F_non-lesional_pre-dose424.6766
GSM1296108G_non-lesional_pre-dose752.4275
GSM1296110H_non-lesional_pre-dose456.465
GSM1296081I_non-lesional_pre-dose221.6455
GSM1296091J_non-lesional_pre-dose1119.6981
GSM1296075K_non-lesional_pre-dose1045.0580
GSM1296112L_non-lesional_pre-dose625.1971
GSM1296100M_non-lesional_pre-dose770.0775
GSM1296087O_non-lesional_pre-dose667.7873
GSM1296118P_non-lesional_pre-dose656.6772
GSM1296114Q_non-lesional_pre-dose625.8771
GSM1296097R_non-lesional_pre-dose997.5579
GSM1296106S_non-lesional_pre-dose735.0574
GSM1296102U_non-lesional_pre-dose555.4969
GSM1296122V_non-lesional_pre-dose716.8774
GSM1296089W_non-lesional_pre-dose76675
GSM1296083X_non-lesional_pre-dose266.8857
GSM1296116Y_non-lesional_pre-dose709.8874
GSM1296085Z_non-lesional_pre-dose409.7864