ProfileGDS5420 / 227448_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 77% 84% 84% 78% 73% 86% 85% 77% 86% 80% 78% 85% 79% 82% 79% 85% 74% 91% 76% 76% 80% 85% 78% 79% 85% 86% 85% 87% 82% 79% 85% 79% 72% 80% 90% 77% 86% 87% 86% 85% 86% 85% 93% 84% 90% 90% 91% 89% 87% 86% 89% 85% 74% 85% 79% 66% 83% 77% 80% 76% 89% 86% 88% 95% 78% 91% 90% 94% 83% 90% 74% 88% 74% 83% 80% 75% 89% 91% 86% 78% 95% 87% 89% 83% 88% 87% 88% 81% 87% 90% 88% 82% 87% 85% 88% 87% 87% 88% 88% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose870.0277
GSM1296119B_lesional_pre-dose1354.5684
GSM1296076C_lesional_pre-dose1479.9884
GSM1296092D_lesional_pre-dose957.6778
GSM1296103E_lesional_pre-dose689.7673
GSM1296078F_lesional_pre-dose1636.0186
GSM1296107G_lesional_pre-dose1458.1985
GSM1296109H_lesional_pre-dose889.2177
GSM1296080I_lesional_pre-dose1637.7886
GSM1296090J_lesional_pre-dose1103.2580
GSM1296074K_lesional_pre-dose931.8378
GSM1296111L_lesional_pre-dose1450.9285
GSM1296099M_lesional_pre-dose1001.3679
GSM1296086O_lesional_pre-dose1251.0982
GSM1296117P_lesional_pre-dose1000.7779
GSM1296113Q_lesional_pre-dose1398.0785
GSM1296096R_lesional_pre-dose727.6874
GSM1296105S_lesional_pre-dose2234.2191
GSM1296098T_lesional_pre-dose830.876
GSM1296101U_lesional_pre-dose818.376
GSM1296121V_lesional_pre-dose1028.1880
GSM1296088W_lesional_pre-dose1504.4885
GSM1296082X_lesional_pre-dose926.8278
GSM1296115Y_lesional_pre-dose980.8679
GSM1296084Z_lesional_pre-dose1462.2885
GSM1296072B_lesional_day81525.6186
GSM1296069L_lesional_day81379.2685
GSM1296071P_lesional_day81615.3287
GSM1296070Y_lesional_day81207.0882
GSM1296073V_lesional_day81004.3879
GSM1296034A_lesional_day151419.2685
GSM1296041G_lesional_day151000.1579
GSM1296035R_lesional_day15652.7672
GSM1296038U_lesional_day151094.9280
GSM1296047B_lesional_day152129.8290
GSM1296039E_lesional_day15863.6877
GSM1296042H_lesional_day151506.8586
GSM1296043L_lesional_day151574.0987
GSM1296037M_lesional_day151549.9486
GSM1296046P_lesional_day151394.3285
GSM1296044Q_lesional_day151540.7486
GSM1296045Y_lesional_day151439.9985
GSM1296025C_lesional_day152801.8393
GSM1296033D_lesional_day151383.5284
GSM1296027I_lesional_day152171.4590
GSM1296032J_lesional_day152086.5590
GSM1296024K_lesional_day152429.2291
GSM1296031W_lesional_day151923.8289
GSM1296028X_lesional_day151758.7387
GSM1296029Z_lesional_day151622.8786
GSM1296026F_lesional_day152095.6789
GSM1296030O_lesional_day151574.0685
GSM1296040S_lesional_day15724.1374
GSM1296036T_lesional_day151462.0785
GSM1296048V_lesional_day151015.1579
GSM1296059A_lesional_day43450.0866
GSM1296066G_lesional_day431290.7383
GSM1296060R_lesional_day43877.2477
GSM1296063U_lesional_day431075.4480
GSM1296064E_lesional_day43820.4976
GSM1296067H_lesional_day431877.3889
GSM1296062M_lesional_day431506.9686
GSM1296068Q_lesional_day431731.1688
GSM1296050C_lesional_day433559.7795
GSM1296057D_lesional_day43963.2278
GSM1296052I_lesional_day432327.2591
GSM1296054J_lesional_day432055.4490
GSM1296049K_lesional_day433114.494
GSM1296055W_lesional_day431285.4183
GSM1296053X_lesional_day432059.6790
GSM1296058Z_lesional_day43748.7674
GSM1296051F_lesional_day431877.9888
GSM1296056O_lesional_day43720.8174
GSM1296065S_lesional_day431286.2583
GSM1296061T_lesional_day431068.8280
GSM1296095A_non-lesional_pre-dose770.8675
GSM1296120B_non-lesional_pre-dose1936.0189
GSM1296077C_non-lesional_pre-dose2440.5791
GSM1296093D_non-lesional_pre-dose1536.1586
GSM1296104E_non-lesional_pre-dose933.5478
GSM1296079F_non-lesional_pre-dose3490.5395
GSM1296108G_non-lesional_pre-dose1658.2687
GSM1296110H_non-lesional_pre-dose1880.4989
GSM1296081I_non-lesional_pre-dose1309.0683
GSM1296091J_non-lesional_pre-dose1924.3688
GSM1296075K_non-lesional_pre-dose1803.8687
GSM1296112L_non-lesional_pre-dose1670.288
GSM1296100M_non-lesional_pre-dose1156.6881
GSM1296087O_non-lesional_pre-dose1775.6687
GSM1296118P_non-lesional_pre-dose2022.3790
GSM1296114Q_non-lesional_pre-dose1784.1788
GSM1296097R_non-lesional_pre-dose1192.8882
GSM1296106S_non-lesional_pre-dose1640.8187
GSM1296102U_non-lesional_pre-dose1453.9385
GSM1296122V_non-lesional_pre-dose1751.2488
GSM1296089W_non-lesional_pre-dose1617.5687
GSM1296083X_non-lesional_pre-dose1658.9987
GSM1296116Y_non-lesional_pre-dose1773.2588
GSM1296085Z_non-lesional_pre-dose1861.4288