ProfileGDS5420 / 227338_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 78% 91% 95% 96% 80% 95% 94% 89% 87% 96% 94% 96% 88% 96% 97% 96% 86% 79% 81% 78% 92% 91% 96% 96% 93% 89% 96% 95% 95% 91% 75% 96% 87% 86% 88% 91% 95% 95% 83% 96% 95% 96% 79% 94% 94% 95% 75% 93% 94% 94% 78% 92% 77% 83% 90% 80% 96% 88% 90% 91% 89% 81% 96% 93% 88% 96% 92% 89% 90% 89% 82% 94% 88% 88% 79% 90% 90% 78% 90% 91% 88% 93% 92% 87% 97% 92% 95% 84% 95% 96% 96% 88% 84% 83% 88% 94% 85% 96% 96% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose971.7278
GSM1296119B_lesional_pre-dose2421.191
GSM1296076C_lesional_pre-dose4045.6195
GSM1296092D_lesional_pre-dose4345.696
GSM1296103E_lesional_pre-dose1056.9680
GSM1296078F_lesional_pre-dose4125.9495
GSM1296107G_lesional_pre-dose3300.7194
GSM1296109H_lesional_pre-dose1979.1789
GSM1296080I_lesional_pre-dose1715.8887
GSM1296090J_lesional_pre-dose4452.996
GSM1296074K_lesional_pre-dose3600.594
GSM1296111L_lesional_pre-dose3845.7696
GSM1296099M_lesional_pre-dose1761.8688
GSM1296086O_lesional_pre-dose4111.7296
GSM1296117P_lesional_pre-dose4256.9997
GSM1296113Q_lesional_pre-dose3805.0396
GSM1296096R_lesional_pre-dose1621.8486
GSM1296105S_lesional_pre-dose1008.0979
GSM1296098T_lesional_pre-dose1133.9581
GSM1296101U_lesional_pre-dose948.4978
GSM1296121V_lesional_pre-dose2577.7392
GSM1296088W_lesional_pre-dose2349.5291
GSM1296082X_lesional_pre-dose4734.2996
GSM1296115Y_lesional_pre-dose4148.8196
GSM1296084Z_lesional_pre-dose2822.4493
GSM1296072B_lesional_day81926.9689
GSM1296069L_lesional_day83574.8996
GSM1296071P_lesional_day83027.5795
GSM1296070Y_lesional_day83286.7595
GSM1296073V_lesional_day82419.6991
GSM1296034A_lesional_day15808.7975
GSM1296041G_lesional_day154017.7896
GSM1296035R_lesional_day151733.5487
GSM1296038U_lesional_day151568.7186
GSM1296047B_lesional_day151798.588
GSM1296039E_lesional_day152469.2591
GSM1296042H_lesional_day153510.695
GSM1296043L_lesional_day153261.0595
GSM1296037M_lesional_day151240.6183
GSM1296046P_lesional_day153674.2996
GSM1296044Q_lesional_day153081.7395
GSM1296045Y_lesional_day153562.4296
GSM1296025C_lesional_day151010.1679
GSM1296033D_lesional_day153003.1194
GSM1296027I_lesional_day153124.894
GSM1296032J_lesional_day153220.7195
GSM1296024K_lesional_day15797.6375
GSM1296031W_lesional_day152601.4993
GSM1296028X_lesional_day152899.9494
GSM1296029Z_lesional_day152892.5594
GSM1296026F_lesional_day15952.2678
GSM1296030O_lesional_day152697.7792
GSM1296040S_lesional_day15871.4577
GSM1296036T_lesional_day151248.7683
GSM1296048V_lesional_day152186.5990
GSM1296059A_lesional_day431097.5580
GSM1296066G_lesional_day43368196
GSM1296060R_lesional_day431840.3388
GSM1296063U_lesional_day432243.1390
GSM1296064E_lesional_day432569.3491
GSM1296067H_lesional_day431884.389
GSM1296062M_lesional_day431150.9381
GSM1296068Q_lesional_day433266.3796
GSM1296050C_lesional_day432867.5993
GSM1296057D_lesional_day431753.7288
GSM1296052I_lesional_day433807.5896
GSM1296054J_lesional_day432399.2192
GSM1296049K_lesional_day431995.4789
GSM1296055W_lesional_day432156.3590
GSM1296053X_lesional_day431956.6289
GSM1296058Z_lesional_day431230.382
GSM1296051F_lesional_day433420.3394
GSM1296056O_lesional_day431924.4588
GSM1296065S_lesional_day431787.9788
GSM1296061T_lesional_day43976.0179
GSM1296095A_non-lesional_pre-dose2200.5690
GSM1296120B_non-lesional_pre-dose2096.2490
GSM1296077C_non-lesional_pre-dose935.6278
GSM1296093D_non-lesional_pre-dose2066.5990
GSM1296104E_non-lesional_pre-dose2602.4891
GSM1296079F_non-lesional_pre-dose1861.8988
GSM1296108G_non-lesional_pre-dose2879.0193
GSM1296110H_non-lesional_pre-dose2248.992
GSM1296081I_non-lesional_pre-dose1762.2787
GSM1296091J_non-lesional_pre-dose4411.8697
GSM1296075K_non-lesional_pre-dose2755.9492
GSM1296112L_non-lesional_pre-dose2939.3895
GSM1296100M_non-lesional_pre-dose1385.9984
GSM1296087O_non-lesional_pre-dose3779.9595
GSM1296118P_non-lesional_pre-dose3332.8496
GSM1296114Q_non-lesional_pre-dose3787.5296
GSM1296097R_non-lesional_pre-dose1824.2188
GSM1296106S_non-lesional_pre-dose1352.1984
GSM1296102U_non-lesional_pre-dose1255.9383
GSM1296122V_non-lesional_pre-dose1801.2888
GSM1296089W_non-lesional_pre-dose2906.9894
GSM1296083X_non-lesional_pre-dose1485.1285
GSM1296116Y_non-lesional_pre-dose3288.0896
GSM1296085Z_non-lesional_pre-dose3639.5896