ProfileGDS5420 / 227196_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 53% 80% 81% 86% 60% 71% 80% 40% 62% 88% 74% 75% 78% 79% 70% 68% 70% 87% 49% 58% 74% 69% 64% 81% 83% 85% 83% 82% 87% 69% 53% 56% 57% 69% 91% 47% 61% 87% 96% 88% 74% 89% 82% 92% 93% 96% 90% 86% 93% 86% 64% 81% 62% 49% 71% 61% 75% 75% 71% 77% 63% 84% 86% 92% 92% 90% 94% 88% 76% 87% 78% 86% 64% 85% 35% 52% 92% 87% 93% 86% 90% 83% 74% 97% 96% 88% 92% 97% 94% 96% 82% 83% 87% 62% 84% 90% 89% 90% 97% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose204.8953
GSM1296119B_lesional_pre-dose105780
GSM1296076C_lesional_pre-dose1187.181
GSM1296092D_lesional_pre-dose1690.9186
GSM1296103E_lesional_pre-dose318.7760
GSM1296078F_lesional_pre-dose591.8871
GSM1296107G_lesional_pre-dose1021.7280
GSM1296109H_lesional_pre-dose104.9340
GSM1296080I_lesional_pre-dose354.1662
GSM1296090J_lesional_pre-dose1952.0288
GSM1296074K_lesional_pre-dose713.9174
GSM1296111L_lesional_pre-dose758.1175
GSM1296099M_lesional_pre-dose935.278
GSM1296086O_lesional_pre-dose1000.0179
GSM1296117P_lesional_pre-dose561.2670
GSM1296113Q_lesional_pre-dose528.268
GSM1296096R_lesional_pre-dose589.2570
GSM1296105S_lesional_pre-dose1663.8687
GSM1296098T_lesional_pre-dose163.6949
GSM1296101U_lesional_pre-dose285.0758
GSM1296121V_lesional_pre-dose736.5974
GSM1296088W_lesional_pre-dose529.6669
GSM1296082X_lesional_pre-dose387.8364
GSM1296115Y_lesional_pre-dose1140.8181
GSM1296084Z_lesional_pre-dose1325.3983
GSM1296072B_lesional_day81409.0585
GSM1296069L_lesional_day81214.1183
GSM1296071P_lesional_day81132.5982
GSM1296070Y_lesional_day81611.187
GSM1296073V_lesional_day8535.3369
GSM1296034A_lesional_day15223.8453
GSM1296041G_lesional_day15247.6956
GSM1296035R_lesional_day15268.8657
GSM1296038U_lesional_day15537.7669
GSM1296047B_lesional_day152286.391
GSM1296039E_lesional_day15137.4847
GSM1296042H_lesional_day15345.6461
GSM1296043L_lesional_day151583.3287
GSM1296037M_lesional_day154117.796
GSM1296046P_lesional_day151747.388
GSM1296044Q_lesional_day15746.8974
GSM1296045Y_lesional_day151840.8589
GSM1296025C_lesional_day151242.3982
GSM1296033D_lesional_day152471.8792
GSM1296027I_lesional_day152970.1493
GSM1296032J_lesional_day153865.5196
GSM1296024K_lesional_day152104.7790
GSM1296031W_lesional_day151537.5486
GSM1296028X_lesional_day152754.7893
GSM1296029Z_lesional_day151547.0886
GSM1296026F_lesional_day15399.2864
GSM1296030O_lesional_day151137.581
GSM1296040S_lesional_day15372.4362
GSM1296036T_lesional_day15178.7349
GSM1296048V_lesional_day15619.2371
GSM1296059A_lesional_day43324.4861
GSM1296066G_lesional_day43780.9975
GSM1296060R_lesional_day43781.275
GSM1296063U_lesional_day43608.5971
GSM1296064E_lesional_day43872.9477
GSM1296067H_lesional_day43409.463
GSM1296062M_lesional_day431400.5984
GSM1296068Q_lesional_day431448.9986
GSM1296050C_lesional_day432671.3792
GSM1296057D_lesional_day432403.0792
GSM1296052I_lesional_day432282.9290
GSM1296054J_lesional_day432767.6494
GSM1296049K_lesional_day431897.6888
GSM1296055W_lesional_day43847.2376
GSM1296053X_lesional_day431651.2287
GSM1296058Z_lesional_day43944.0178
GSM1296051F_lesional_day431699.1286
GSM1296056O_lesional_day43380.5364
GSM1296065S_lesional_day431446.6185
GSM1296061T_lesional_day4367.1935
GSM1296095A_non-lesional_pre-dose187.7552
GSM1296120B_non-lesional_pre-dose2532.9692
GSM1296077C_non-lesional_pre-dose1778.9287
GSM1296093D_non-lesional_pre-dose2596.9593
GSM1296104E_non-lesional_pre-dose1667.1986
GSM1296079F_non-lesional_pre-dose2151.8190
GSM1296108G_non-lesional_pre-dose1223.883
GSM1296110H_non-lesional_pre-dose747.2974
GSM1296081I_non-lesional_pre-dose4706.5397
GSM1296091J_non-lesional_pre-dose4010.2496
GSM1296075K_non-lesional_pre-dose1980.4788
GSM1296112L_non-lesional_pre-dose2337.292
GSM1296100M_non-lesional_pre-dose5203.3997
GSM1296087O_non-lesional_pre-dose3177.2894
GSM1296118P_non-lesional_pre-dose3572.5196
GSM1296114Q_non-lesional_pre-dose1170.8582
GSM1296097R_non-lesional_pre-dose1288.8483
GSM1296106S_non-lesional_pre-dose1640.2987
GSM1296102U_non-lesional_pre-dose371.5362
GSM1296122V_non-lesional_pre-dose1293.8184
GSM1296089W_non-lesional_pre-dose2101.1790
GSM1296083X_non-lesional_pre-dose2016.1189
GSM1296116Y_non-lesional_pre-dose2037.0990
GSM1296085Z_non-lesional_pre-dose4382.297