ProfileGDS5420 / 227110_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 86% 88% 91% 86% 86% 91% 87% 85% 88% 86% 89% 86% 91% 91% 86% 82% 89% 90% 82% 85% 86% 90% 89% 86% 87% 84% 84% 83% 84% 86% 76% 87% 83% 89% 85% 85% 83% 86% 83% 85% 84% 83% 87% 87% 87% 83% 85% 83% 87% 86% 90% 90% 90% 84% 82% 88% 85% 86% 88% 86% 82% 87% 81% 90% 80% 86% 82% 85% 83% 86% 79% 90% 87% 88% 83% 85% 85% 89% 83% 84% 88% 84% 83% 82% 86% 91% 81% 84% 90% 83% 83% 85% 87% 82% 81% 82% 82% 85% 83% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose1606.6786
GSM1296119B_lesional_pre-dose1826.1188
GSM1296076C_lesional_pre-dose2484.5791
GSM1296092D_lesional_pre-dose1732.4686
GSM1296103E_lesional_pre-dose1638.4186
GSM1296078F_lesional_pre-dose2693.7891
GSM1296107G_lesional_pre-dose1636.6587
GSM1296109H_lesional_pre-dose1408.2685
GSM1296080I_lesional_pre-dose1923.788
GSM1296090J_lesional_pre-dose1653.3186
GSM1296074K_lesional_pre-dose2182.8589
GSM1296111L_lesional_pre-dose1570.1386
GSM1296099M_lesional_pre-dose2315.1291
GSM1296086O_lesional_pre-dose2572.6291
GSM1296117P_lesional_pre-dose1517.1486
GSM1296113Q_lesional_pre-dose1171.7382
GSM1296096R_lesional_pre-dose2023.1989
GSM1296105S_lesional_pre-dose2131.4490
GSM1296098T_lesional_pre-dose1161.8282
GSM1296101U_lesional_pre-dose1496.4385
GSM1296121V_lesional_pre-dose1527.2486
GSM1296088W_lesional_pre-dose2206.2290
GSM1296082X_lesional_pre-dose2108.7789
GSM1296115Y_lesional_pre-dose1583.7486
GSM1296084Z_lesional_pre-dose1759.587
GSM1296072B_lesional_day81326.6584
GSM1296069L_lesional_day81296.3184
GSM1296071P_lesional_day81258.4383
GSM1296070Y_lesional_day81296.2184
GSM1296073V_lesional_day81613.3286
GSM1296034A_lesional_day15829.1376
GSM1296041G_lesional_day151666.0387
GSM1296035R_lesional_day151289.2483
GSM1296038U_lesional_day152018.289
GSM1296047B_lesional_day151446.6685
GSM1296039E_lesional_day151555.685
GSM1296042H_lesional_day151276.9683
GSM1296043L_lesional_day151493.7586
GSM1296037M_lesional_day151283.0783
GSM1296046P_lesional_day151379.685
GSM1296044Q_lesional_day151314.3384
GSM1296045Y_lesional_day151206.1883
GSM1296025C_lesional_day151673.5587
GSM1296033D_lesional_day151697.2587
GSM1296027I_lesional_day151810.4487
GSM1296032J_lesional_day151277.7783
GSM1296024K_lesional_day151548.2485
GSM1296031W_lesional_day151266.9383
GSM1296028X_lesional_day151746.787
GSM1296029Z_lesional_day151584.286
GSM1296026F_lesional_day152182.7490
GSM1296030O_lesional_day152320.1790
GSM1296040S_lesional_day152050.8390
GSM1296036T_lesional_day151339.3584
GSM1296048V_lesional_day151187.3282
GSM1296059A_lesional_day431819.9188
GSM1296066G_lesional_day431406.2985
GSM1296060R_lesional_day431570.386
GSM1296063U_lesional_day431923.1688
GSM1296064E_lesional_day431707.5286
GSM1296067H_lesional_day431181.5982
GSM1296062M_lesional_day431721.0187
GSM1296068Q_lesional_day431098.1281
GSM1296050C_lesional_day432267.890
GSM1296057D_lesional_day431091.9480
GSM1296052I_lesional_day431662.3786
GSM1296054J_lesional_day431184.5682
GSM1296049K_lesional_day431501.0485
GSM1296055W_lesional_day431230.583
GSM1296053X_lesional_day431532.2386
GSM1296058Z_lesional_day431048.979
GSM1296051F_lesional_day432311.1290
GSM1296056O_lesional_day431713.6987
GSM1296065S_lesional_day431750.9488
GSM1296061T_lesional_day431289.5783
GSM1296095A_non-lesional_pre-dose1522.2485
GSM1296120B_non-lesional_pre-dose1454.985
GSM1296077C_non-lesional_pre-dose2019.889
GSM1296093D_non-lesional_pre-dose1300.8183
GSM1296104E_non-lesional_pre-dose1423.4884
GSM1296079F_non-lesional_pre-dose1902.0188
GSM1296108G_non-lesional_pre-dose1325.3584
GSM1296110H_non-lesional_pre-dose1260.4883
GSM1296081I_non-lesional_pre-dose1224.1982
GSM1296091J_non-lesional_pre-dose1634.7186
GSM1296075K_non-lesional_pre-dose246191
GSM1296112L_non-lesional_pre-dose1118.281
GSM1296100M_non-lesional_pre-dose1395.7384
GSM1296087O_non-lesional_pre-dose2283.4490
GSM1296118P_non-lesional_pre-dose1262.3483
GSM1296114Q_non-lesional_pre-dose1241.1683
GSM1296097R_non-lesional_pre-dose1491.1685
GSM1296106S_non-lesional_pre-dose1605.9687
GSM1296102U_non-lesional_pre-dose1197.2282
GSM1296122V_non-lesional_pre-dose1075.2681
GSM1296089W_non-lesional_pre-dose1215.7582
GSM1296083X_non-lesional_pre-dose1241.4782
GSM1296116Y_non-lesional_pre-dose1409.8285
GSM1296085Z_non-lesional_pre-dose1300.183